Patents by Inventor Michelle Devissaguet

Michelle Devissaguet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5332735
    Abstract: Compounds of the general formula (I): ##STR1## where A, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are defined in the description.Medicinal products.
    Type: Grant
    Filed: November 14, 1991
    Date of Patent: July 26, 1994
    Assignee: Adir et Compagnie
    Inventors: Sylvain Rault, Marie P. Foloppe, Max Robba, Michel Boulouard, Pierre Renard, Michelle Devissaguet, Gerard Adam
  • Patent number: 5254548
    Abstract: A compound having an aryltriazine structure selected from those of formula (I): ##STR1## for which the meaning of the substituents Ar, R.sub.1, R.sub.5, R.sub.6, and R.sub.6 ' is given in the description.The compound of the invention is useful as medicinal product for disorders associated with a cholinergic dysfunction.
    Type: Grant
    Filed: January 14, 1992
    Date of Patent: October 19, 1993
    Assignee: Adir et Compagnie
    Inventors: Camille-Georges Wermuth, Jean-Jacques Bourguignon, Isabelle Morin, Pierre Renard, Michelle Devissaguet, Jean-Francois R. de La Faverie, Gerard Adam
  • Patent number: 5242923
    Abstract: The invention relates to the compounds of general formula (I): ##STR1## in which: R.sub.1, R.sub.2, R.sub.3, R.sub.4, A, Z and m are as defined in the description, their isomers, epimers and diastereoisomers,their addition salts with a pharmaceutically acceptable acid and, when R1 and R.sub.2 each represent a hydrogen atom, their addition salts with a pharmaceutically acceptable base.
    Type: Grant
    Filed: February 21, 1992
    Date of Patent: September 7, 1993
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Christine Flouzat, Michelle Devissaguet, Pierre Renard, Daniel H. Caignard, Gerard Adam
  • Patent number: 5190939
    Abstract: The invention relates to compounds of general formula I: ##STR1## in which: R.sub.1 represents a radical of general formula (Z.sub.0), (Z.sub.1), (Z.sub.2), (Z.sub.3) or (Z.sub.4) ##STR2## R.sub.2 represents a methylene radical, a hydroxymethylene radical, a carbonyl radical or a radical of general formula (Y.sub.1), (Y.sub.2), (Y.sub.3) or (Y.sub.4): ##STR3## or, with R.sub.12 and the nitrogen atom to which they are attached, forms a radical of general formula (W): ##STR4## R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9, R.sub.10, R.sub.11, R.sub.12 and n being as defined in the description, medicinal products containing the same and a method-of-treating metabolic ailments therewith.
    Type: Grant
    Filed: March 7, 1991
    Date of Patent: March 2, 1993
    Assignee: Adir et Compagnie
    Inventors: Sylvain Rault, Michel Boulouard, Patrick Dallemagne, Max Robba, Beatrice Guardiola, Michelle Devissaguet
  • Patent number: 5190960
    Abstract: Compounds of general formula (I): ##STR1## in which: R.sub.1 and R.sub.2 each represent a hydrogen atom or, with the nitrogen and oxygen which bear them, form an --O--CO--N link,W represents a halogen atom or a lower alkyl or alkoxy group optionally substituted with one or more halogen atoms, such as trifluoromethyl, and m being between 0 and 3,A is a linear or branched alkyl radical comprising from 1 to 6 carbon atoms,R.sub.3 and R.sub.4 are defined in the description.
    Type: Grant
    Filed: November 12, 1991
    Date of Patent: March 2, 1993
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Christine Flouzat, Daniel H. Caignard, Pierre Renard, Michelle Devissaguet, Beatrice Guardiola
  • Patent number: 5179091
    Abstract: Compounds of general formula (I): in which: ##STR1## R.sub.1, X, Y, Z, T, R.sub.2, R.sub.3 and R.sub.4 are defined in the description. Medicinal products.
    Type: Grant
    Filed: June 3, 1991
    Date of Patent: January 12, 1993
    Assignee: Adir et Compagnie
    Inventors: Daniel Lesieur, Daniel H. Caignard, Isabelle Lesieur, Michelle Devissaguet, Beatrice Guardiola
  • Patent number: 5155116
    Abstract: Compounds of general formula (I): ##STR1## in which: R.sub.1 and R.sub.2 each represent a hydrogen atom or, with the nitrogen and oxygen which bear them, form an --O--CO--N link,W represents a halogen atom or a lower alkyl or alkoxy group optionally substituted with one or more halogen atoms, such as trifluoromethyl, and m being between 0 and 3,A is a linear or branched alkyl radical comprising from 1 to 6 carbon atoms,R.sub.3 and R.sub.4 are defined in the description have medicinal properties.
    Type: Grant
    Filed: June 6, 1991
    Date of Patent: October 13, 1992
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Christine Flouzat, Daniel H. Caignard, Pierre Renard, Michelle Devissaguet, Beatrice Guardiola
  • Patent number: 5147883
    Abstract: Compounds of general formula (I): ##STR1## in which: R.sub.1 represents a hydrogen atom or a lower alkyl group,A represents a hydrogen atom, and in this case B represents a group CO-G, G being:either a heteroaryl group selected from furan, indole, pyrrole, pyridine, quinoline, isoquinoline and benzofuran, optionally substituted with one or more lower alkyl or lower alkoxy groups or a halogen atoms,or a linear or branched lower alkyl group substituted with a carboxyl group,or a linear or branched lower alkenyl group substituted with a carboxyl group,or a phenyl or naphthyl group substituted with a carboxyl group,or alternatively A forms with B a group CO(CH.sub.2).sub.n CH(CH.sub.
    Type: Grant
    Filed: May 31, 1991
    Date of Patent: September 15, 1992
    Assignee: Adir et Compagnie
    Inventors: Hocine Aichaioui, Daniel Lesieur, Charles Lespagnol, Michelle Devissaguet, Beatrice Guardiola
  • Patent number: 5130311
    Abstract: The invention relates to the analgesic compounds of general formula (I): ##STR1## in which: R.sub.1, R.sub.2, R.sub.3, R.sub.4, A, Z and m are as defined in the description, their isomers, epimers and diastereoisomers, their addition salts with a pharmaceutically acceptable acid and, when R.sub.1 and R.sub.2 each represent a hydrogen atom, their addition salts with a pharmaceutically acceptable base.
    Type: Grant
    Filed: November 15, 1991
    Date of Patent: July 14, 1992
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Christine Flouzat, Michelle Devissaguet, Pierre Renard, Daniel H. Caignard, Gerard Adam
  • Patent number: 5130301
    Abstract: Novel 4H-pyrrolo[1,2-a]thieno[2,3-f][1,4]diazepine which are usable as a medicinal product and correspond to the general formula (I): ##STR1## in which: R.sub.1, R.sub.2, R.sub.3 and R.sub.4 have the same meaning as given in the specification.These compounds, as well as their physiologically tolerable salts, may be used in therapy, in particular in the treatment of disorders linked to hypoxemia and to certain metabolic disorders.
    Type: Grant
    Filed: March 26, 1991
    Date of Patent: July 14, 1992
    Assignee: Adir et Compagnie
    Inventors: Sylvain Rault, Michel Boulouard, Max Robba, Beatrice Guardiola, Michelle Devissaguet
  • Patent number: 5084469
    Abstract: Compounds of general formula (I): ##STR1## in which: R.sub.1 represents a hydrogen atom or a lower alkyl group, andR.sub.2 represents a substituted or unsubstituted alkyl, a phenyl or a substituted or unsubstituted heteroaryl,their enantiomers, diastereoisomers and epimers and their addition salts with a pharmaceutically acceptable base when R.sub.1 represents a hydrogen atom or when R.sub.2 comprises a carboxylic acid group. Medicinal products.
    Type: Grant
    Filed: November 9, 1990
    Date of Patent: January 28, 1992
    Assignee: Adir et Compagnie
    Inventors: Isabelle Lesieur, Said Yous, Michelle Devissaguet, Yannis Tsouderos
  • Patent number: 4407801
    Abstract: The subject of the invention is a novel pharmaceutical composition, especially having an anti-ischaemic action, containing, in combination, a high dosage (within the range of from 20 to 80 mg) of the dihydrochloride (or another mineral or organic salt) of 1-(2,3,4-trimethoxybenzyl)piperazine and a disintegrating agent, such as mannitol or sodium carboxymethyl starch, that has the effect of liberating the salt of 1-(2,3,4-trimethoxybenzyl)piperazine virtually instantaneously in the organism, this composition being, furthermore, advantageously enclosed in a thin coating film or held together by a binder that is itself readily disintegrated in situ in the organism in such a manner that it makes possible a "flash" action, that is to say a virtually instantaneous action, of the above-mentioned salt in situ. This composition is administered to the patient at a dosage of from 20 to 80 mg/day.
    Type: Grant
    Filed: September 28, 1981
    Date of Patent: October 4, 1983
    Assignee: Science Union Et Cie
    Inventors: Jean-Claude Arnaud, Michelle Devissaguet