Patents by Inventor Michelle Dutra

Michelle Dutra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYNUCLEOTIDES ENCODING INTEGRIN BETA-6 AND METHODS OF USE THEREOF
    Publication number: 20250041393
    Abstract: The disclosure features lipid nanoparticle (LNP) compositions ITB6 molecules and uses thereof. The LNP compositions of the present disclosure comprise mRNA therapeutics encoding ITB6 polypeptides. The LNP compositions of the present disclosure can reprogram dendritic cells, suppress T cells and/or induce immune tolerance in vivo.
    Type: Application
    Filed: November 1, 2022
    Publication date: February 6, 2025
    Inventors: Eric Yi-Chun Huang, Paul Stein, Laurie Kenney, Michelle Dutra, Myoungjoo Kim, Pranitha Vangala
  • MRNAS ENCODING CHIMERIC METABOLIC REPROGRAMMING POLYPEPTIDES AND USES THEREOF
    Publication number: 20240401006
    Abstract: The disclosure features lipid nanoparticle (LNP) compositions comprising metabolic reprogramming molecules and membrane anchoring moieties and uses thereof. The LNP compositions of the present disclosure comprise mRNA therapeutics encoding metabolic reprogramming polypeptides, e.g., IDO or TDO and membrane anchoring moieties. The LNP compositions of the present disclosure can reprogram myeloid and/or dendritic cells, suppress T cells and/or induce immune tolerance in vivo.
    Type: Application
    Filed: August 4, 2022
    Publication date: December 5, 2024
    Inventors: Laurie Kenney, Eric Yi-Chun Huang, Paul Stein, Michelle Dutra, Seymour de Picciotto, Susamma Canali, Sze-Wah Tse, Jared Iacovelli