Patents by Inventor MICHELLE M. MADER

MICHELLE M. MADER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTAGONIST ANTIBODIES AGAINST GDF-8 AND USES THEREFOR
    Publication number: 20200277365
    Abstract: The disclosure provides improved neutralizing anti-GDF-8 antibodies capable of substantially higher levels of expression in host cells compared to previous anti-GDF-8 antibodies. Also provided are methods of using compositions comprising such antibodies to increase muscle mass or strength, and to treat or prevent muscular disorders, neuromuscular disorders, metabolic disorders, adipose tissue disorders or bone disorders.
    Type: Application
    Filed: November 13, 2019
    Publication date: September 3, 2020
    Inventors: MICHELLE M. MADER, JAMES R. APGAR, KEVIN D. PARRIS
  • ANTAGONIST ANTIBODIES AGAINST GDF-8 AND USES THEREFOR
    Publication number: 20180057579
    Abstract: The disclosure provides improved neutralizing anti-GDF-8 antibodies capable of substantially higher levels of expression in host cells compared to previous anti-GDF-8 antibodies. Also provided are methods of using compositions comprising such antibodies to increase muscle mass or strength, and to treat or prevent muscular disorders, neuromuscular disorders, metabolic disorders, adipose tissue disorders or bone disorders.
    Type: Application
    Filed: August 1, 2017
    Publication date: March 1, 2018
    Inventors: MICHELLE M. MADER, JAMES R. APGAR, KEVIN D. PARRIS
  • Antagonist antibodies against GDF-8 and uses therefor
    Patent number: 9751937
    Abstract: The disclosure provides improved neutralizing anti-GDF-8 antibodies capable of substantially higher levels of expression in host cells compared to previous anti-GDF-8 antibodies. Also provided are methods of using compositions comprising such antibodies to increase muscle mass or strength, and to treat or prevent muscular disorders, neuromuscular disorders, metabolic disorders, adipose tissue disorders or bone disorders.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: September 5, 2017
    Assignee: PFIZER INC.
    Inventors: Michelle M. Mader, James R. Apgar, Kevin D. Parris
  • ANTAGONIST ANTIBODIES AGAINST GDF-8 AND USES THEREFOR
    Publication number: 20150337032
    Abstract: The disclosure provides improved neutralizing anti-GDF-8 antibodies capable of substantially higher levels of expression in host cells compared to previous anti-GDF-8 antibodies. Also provided are methods of using compositions comprising such antibodies to increase muscle mass or strength, and to treat or prevent muscular disorders, neuromuscular disorders, metabolic disorders, adipose tissue disorders or bone disorders.
    Type: Application
    Filed: February 19, 2015
    Publication date: November 26, 2015
    Inventors: MICHELLE M. MADER, JAMES R. APGAR, KEVIN D. PARRIS
  • Antagonist antibodies against GDF-8 and uses therefor
    Patent number: 8992913
    Abstract: The disclosure provides improved neutralizing anti-GDF-8 antibodies capable of substantially higher levels of expression in host cells compared to previous anti-GDF-8 antibodies. Also provided are methods of using compositions comprising such antibodies to increase muscle mass or strength, and to treat or prevent muscular disorders, neuromuscular disorders, metabolic disorders, adipose tissue disorders or bone disorders.
    Type: Grant
    Filed: June 12, 2013
    Date of Patent: March 31, 2015
    Assignee: Pfizer Inc.
    Inventors: Michelle M. Mader, James R. Apgar, Kevin D. Parris
  • ANTAGONIST ANTIBODIES AGAINST GDF-8 AND USES THEREFOR
    Publication number: 20130336982
    Abstract: The disclosure provides improved neutralizing anti-GDF-8 antibodies capable of substantially higher levels of expression in host cells compared to previous anti-GDF-8 antibodies. Also provided are methods of using compositions comprising such antibodies to increase muscle mass or strength, and to treat or prevent muscular disorders, neuromuscular disorders, metabolic disorders, adipose tissue disorders or bone disorders.
    Type: Application
    Filed: June 12, 2013
    Publication date: December 19, 2013
    Inventors: MICHELLE M. MADER, JAMES R. APGAR, KEVIN D. PARRIS