Patents by Inventor Michelle Manvell

Michelle Manvell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Viral core protein-cationic lipid-nucleic acid-delivery complexes
    Publication number: 20090209037
    Abstract: A nucleic acid delivery complex is provided which comprises a condensed polypeptide/nucleic acid complex and a cationic lipid wherein the complex comprises (a) a nucleic acid sequence of interest (NOI); and (b) one or more viral nucleic acid packaging polypeptides, or derivatives thereof, said polypeptides or derivatives thereof being (i) capable of binding to the NOI; and (ii) capable of condensing the NOI; and wherein the NOI is heterologous to the polypeptide. Also provided is a method of introducing an NOI into a cell using the delivery vector.
    Type: Application
    Filed: October 30, 2008
    Publication date: August 20, 2009
    Inventors: Toshiaki Tagawa, David Andrew Miller, Eric Perouzel, Karl Murray, Michelle Manvell, Eric Alton, David Matthews, Willie Russell
  • Viral core protein-cationic lipid-nucleic acid-delivery complexes
    Publication number: 20030153081
    Abstract: A nucleic acid delivery complex is provided which comprises a condensed polypeptide/nucleic acid complex and a cationic lipid wherein the complex comprises (a) a nucleic acide sequence of interest (NOI); and (b) one or more viral nucleic acid packaging polypeptides, or derivatives thereof, said polypeptides or derivatives thereof being (i) capable of binding to the NOI; and (ii) capable of condensing the NOI; and wherein the NOI is heterologous to the polypeptide. Also provided is a method of introducing an NOI into a cell using the delivery vector.
    Type: Application
    Filed: January 13, 2003
    Publication date: August 14, 2003
    Inventors: Toshiaki Tagawa, David Andrew Miller, Eric Perouzel, Karl Murray, Michelle Manvell, Eric Alton, David Matthews, Willie Russell