Patents by Inventor Michelle MCCLEMENTS

Michelle MCCLEMENTS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DUAL OVERLAPPING ADENO-ASSOCIATED VIRAL VECTOR SYSTEM FOR EXPRESSING ABCA4
    Publication number: 20190309326
    Abstract: The present invention provides an adeno-associated viral (AAV) vector system for expressing a human ABCA4 protein in a target cell, the AAV vector system comprising a first AAV vector comprising a first nucleic acid sequence and a second AAV vector comprising a second nucleic acid sequence; wherein the first nucleic acid sequence comprises a 5? end portion of an ABCA4 coding sequence (CDS) and the second nucleic acid sequence comprises a 3? end portion of an ABCA4 CDS, and the 5? end portion and the 3? end portion together encompass the entire ABCA4 CDS; wherein the first nucleic acid sequence comprises a sequence of contiguous nucleotides corresponding to nucleotides 105 to 3597 of SEQ ID NO: 1; wherein the second nucleic acid sequence comprises a sequence of contiguous nucleotides corresponding to nucleotides 3806 to 6926 of SEQ ID NO: 1; wherein the first nucleic acid sequence and the second nucleic acid sequence each comprise a region of sequence overlap with the other; and wherein the region of sequence
    Type: Application
    Filed: June 14, 2017
    Publication date: October 10, 2019
    Inventors: Robert MACLAREN, Michelle MCCLEMENTS