Abstract: An apparatus and method for generating a fused scan image from a plurality of anatomical scan images of a patient. A tracking system is used to track the physical position and orientation of a scanner transducer, such as an ultrasound probe, which is used to obtain the anatomical scan images. The tracking system may also be used to track markers positioned on the patient for tracking anatomical movement of the patient. An image-processing based fusion is applied to the plurality of anatomical scan images based on the tracked position and orientation of the scanner transducer and the tracked patient anatomical movement to generate a fused scan image. The anatomical movement may comprise respiratory movement of the patient. An electrocardiogram (ECG) signal from the patient may be used to time synchronize tracking information generated by the tracking system with the plurality of anatomical scan images.

Abstract: A time series of image frames in an anatomical scan is segmented. An image frame k in the time series of image frames is manually segmented. A non-rigid registration is then performed between the image frame k and a next image frame k+1 in the time series of image frames. A segmentation on the image frame k+1 is computed based on the non-rigid registration. Each subsequent image frame k+n in the time series of image frames is iteratively segmented using non-rigid registration with the segmented previous image frame k+(n?1) in the time series of image frames.

Abstract: A time series of image frames in an anatomical scan is segmented. An image frame k in the time series of image frames is manually segmented. A non-rigid registration is then performed between the image frame k and a next image frame k+1 in the time series of image frames. A segmentation on the image frame k+1 is computed based on the non-rigid registration. Each subsequent image frame k+n in the time series of image frames is iteratively segmented using non-rigid registration with the segmented previous image frame k+(n?1) in the time series of image frames.

Abstract: A delivery system and method for delivering an aerosol drug to an infant. The delivery device comprises a) a diagnostic module configured to provide geometrical properties of the nasal airway of the infant as output; b) a dosing system configured to produce an aerosol drug dose, based upon the output of the diagnostic module, that is predicted to ensure that a desired amount of the aerosol drug dose reaches the lungs of the infant in use; and c) an infant facemask connected to receive the aerosol drug dose from the dosing system for supply of the aerosol drug dose to the infant.