Patents by Inventor Michelle O'MALLEY

Michelle O'MALLEY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230002454
    Abstract: The present invention provides for a hybrid sugar transporter having an altered sugar transporter activity and comprising at least a first transmembrane domain (TMD) from a first sugar transporter and a second TMD from a second sugar transporter, wherein the first sugar transporter and the second sugar transporter are heterologous to each other.
    Type: Application
    Filed: December 10, 2021
    Publication date: January 5, 2023
    Inventors: Michelle A. O'Malley, Igor A. Podolsky, Susanna Seppala
  • Publication number: 20210269492
    Abstract: Provided herein are novel proteins and protein domains from newly discovered anaerobic fungal species. The anaerobic fungal species have unique enzymatic capabilities, including the ability to digest diverse lignocellulosic biomass feedstocks and to synthesize secondary metabolites. The scope of the invention encompasses novel engineered proteins comprising glycoside hydrolase enzymes, dockerin domains, carbohydrate binding domains, and polyketide synthase enzymes. The invention further encompasses artificial cellulosomes comprising novel proteins and domains of the invention. The scope of the invention further includes novel nucleic acid sequences coding for the engineered proteins of the invention, and methods of using such engineered organisms to degrade lignocellulosic biomass and to create polyketides.
    Type: Application
    Filed: May 17, 2021
    Publication date: September 2, 2021
    Applicant: The Regents of the University of California
    Inventors: Michelle O'Malley, Kevin Solomon, Charles Haitjema
  • Patent number: 11021524
    Abstract: Provided herein are novel proteins and protein domains from newly discovered anaerobic fungal species. The anaerobic fungal species have unique enzymatic capabilities, including the ability to digest diverse lignocellulosic biomass feedstocks and to synthesize secondary metabolites. The scope of the invention encompasses novel engineered proteins comprising glycoside hydrolase enzymes, dockerin domains, carbohydrate binding domains, and polyketide synthase enzymes. The invention further encompasses artificial cellulosomes comprising novel proteins and domains of the invention. The scope of the invention further includes novel nucleic acid sequences coding for the engineered proteins of the invention, and methods of using such engineered organisms to degrade lignocellulosic biomass and to create polyketides.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: June 1, 2021
    Assignee: The Regents of the University of California
    Inventors: Michelle O'Malley, Kevin Solomon, Charles Haitjema
  • Publication number: 20200299338
    Abstract: Provided herein are novel proteins and protein domains from newly discovered anaerobic fungal species. The anaerobic fungal species have unique enzymatic capabilities, including the ability to digest diverse lignocellulosic biomass feedstocks and to synthesize secondary metabolites. The scope of the invention encompasses novel engineered proteins comprising glycoside hydrolase enzymes, dockerin domains, carbohydrate binding domains, and polyketide synthase enzymes. The invention further encompasses artificial cellulosomes comprising novel proteins and domains of the invention. The scope of the invention further includes novel nucleic acid sequences coding for the engineered proteins of the invention, and methods of using such engineered organisms to degrade lignocellulosic biomass and to create polyketides.
    Type: Application
    Filed: June 10, 2020
    Publication date: September 24, 2020
    Applicant: The Regents of the University of California
    Inventors: Michelle O'Malley, Kevin Solomon, Charles Haitjema
  • Patent number: 10717768
    Abstract: Provided herein are novel proteins and protein domains from newly discovered anaerobic fungal species. The anaerobic fungal species have unique enzymatic capabilities, including the ability to digest diverse lignocellulosic biomass feedstocks and to synthesize secondary metabolites. The scope of the invention encompasses novel engineered proteins comprising glycoside hydrolase enzymes, dockerin domains, carbohydrate binding domains, and polyketide synthase enzymes. The invention further encompasses artificial cellulosomes comprising novel proteins and domains of the invention. The scope of the invention further includes novel nucleic acid sequences coding for the engineered proteins of the invention, and methods of using such engineered organisms to degrade lignocellulosic biomass and to create polyketides.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: July 21, 2020
    Assignee: The Regents of the University of California
    Inventors: Michelle O'Malley, Kevin Solomon, Charles Haitjema
  • Patent number: 10676766
    Abstract: The invention relates to an engineered eukaryotic microorganism into which a gene encoding an acyl-CoA dehydrogenase is introduced and a method for producing methacrylic acid esters such as MMA and MMA-CoA and precursors thereof using the microorganism.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: June 9, 2020
    Assignees: The Regents of the University of California, Mitsubishi Chemical Corporation
    Inventors: Michelle O'Malley, Kevin Solomon, Wataru Mizunashi, Fujio Yu
  • Publication number: 20180362597
    Abstract: Provided herein are novel proteins and protein domains from newly discovered anaerobic fungal species. The anaerobic fungal species have unique enzymatic capabilities, including the ability to digest diverse lignocellulosic biomass feedstocks and to synthesize secondary metabolites. The scope of the invention encompasses novel engineered proteins comprising glycoside hydrolase enzymes, dockerin domains, carbohydrate binding domains, and polyketide synthase enzymes. The invention further encompasses artificial cellulosomes comprising novel proteins and domains of the invention. The scope of the invention further includes novel nucleic acid sequences coding for the engineered proteins of the invention, and methods of using such engineered organisms to degrade lignocellulosic biomass and to create polyketides.
    Type: Application
    Filed: December 8, 2016
    Publication date: December 20, 2018
    Applicant: The Regents of the University of California
    Inventors: Michelle O'Malley, Kevin Solomon, Charles Haitjema
  • Publication number: 20180346942
    Abstract: The invention relates to an engineered eukaryotic microorganism into which a gene encoding an acyl-CoA dehydrogenase is introduced and a method for producing methacrylic acid esters such as MMA and MMA-CoA and precursors thereof using the microorganism.
    Type: Application
    Filed: April 20, 2018
    Publication date: December 6, 2018
    Applicants: The Regents of the University of California, Mitsubishi Chemical Corporation
    Inventors: Michelle O'MALLEY, Kevin SOLOMON, Wataru MIZUNASHI, Fujio YU