Patents by Inventor Michelle Scalley-Kim

Michelle Scalley-Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF ANTI-PACAP ANTIBODIES AND ANTIGEN BINDING FRAGMENTS THEREOF FOR TREATMENT, PREVENTION, OR INHIBITION OF PHOTOPHOBIA
    Publication number: 20160376363
    Abstract: This invention relates to methods of screening for anti-PACAP antibodies, or anti-PACAP receptor antibodies, and antigen binding fragments thereof, for potential use in treating or preventing PACAP-associated photophobia or light aversion, and therapeutic compositions containing and methods of using anti-PACAP antibodies, or anti-PACAP receptor antibodies, and antigen binding fragments thereof.
    Type: Application
    Filed: April 15, 2016
    Publication date: December 29, 2016
    Inventors: Adisa KUBURAS, Bianca MASON, Levi P. SOWERS, Andrew F. RUSSO, Maria-Cristina LOOMIS, Leon F. GARCIA-MARTINEZ, Benjamin H. DUTZAR, Daniel S. ALLISON, Lee HENDRICKS, Ethan W. OJALA, Pei FAN, Jeffrey T.L. SMITH, John A. LATHAM, Charlie KARASEK, Jenny MULLIGAN, Michelle SCALLEY-KIM, Erica STEWART, Vanessa Lisbeth RUBIN, Jens J. BILLGREN
  • USE OF ANTI-PACAP ANTIBODIES AND ANTIGEN BINDING FRAGMENTS THEREOF FOR TREATMENT, PREVENTION, OR INHIBITION OF PHOTOPHOBIA
    Publication number: 20160361441
    Abstract: This invention relates to methods of screening for anti-PACAP antibodies, or anti-PACAP receptor antibodies, and antigen binding fragments thereof, for potential use in treating or preventing PACAP-associated photophobia or light aversion, and therapeutic compositions containing and methods of using anti-PACAP antibodies, or anti-PACAP receptor antibodies, and antigen binding fragments thereof.
    Type: Application
    Filed: April 15, 2016
    Publication date: December 15, 2016
    Inventors: Adisa KUBURAS, Bianca MASON, Levi P. SOWERS, Andrew F. RUSSO, Maria-Cristina LOOMIS, Leon F. GARCIA-MARTINEZ, Benjamin H. DUTZAR, Daniel S. ALLISON, Lee HENDRICKS, Ethan W. OJALA, Pei FAN, Jeffrey T.L. SMITH, John A. LATHAM, Charlie KARASEK, Jenny MULLIGAN, Michelle SCALLEY-KIM, Erica STEWART, Vanessa Lisbeth RUBIN, Jens J. BILLGREN
  • ANTI-PACAP ANTIBODIES AND USES THEREOF
    Publication number: 20160362488
    Abstract: The present invention is directed to antagonistic antibodies and antigen binding fragments thereof having binding specificity for PACAP. These antibodies inhibit, block or neutralize at least one biological effect associated with PACAP, e.g., vasodilation. In exemplary embodiments these antibodies and antigen binding fragments thereof may comprise specific VH, VL, and CDR polypeptides described herein. In some embodiments these antibodies and antigen binding fragments thereof bind to and/or compete for binding to specific epitope(s) on human PACAP. The invention is further directed to using these antagonistic anti-PACAP antibodies, and binding fragments thereof, for the diagnosis, assessment, and treatment of diseases and disorders associated with PACAP and conditions where antagonism of PACAP-related activities, such as vasodilation, mast cell degranulation, and/or neuronal activation, are therapeutically beneficial, e.g., headache and migraine indications.
    Type: Application
    Filed: April 15, 2016
    Publication date: December 15, 2016
    Inventors: Maria-Cristina LOOMIS, Leon F. Garcia-Martinez, Benjamin H. Dutzar, Daniel S. Allison, Lee Hendricks, Ethan W. Ojala, Pei Fan, Jeffrey T.L. Smith, John A. Latham, Charlie Karasek, Jenny Mulligan, Michelle Scalley-Kim, Erica Stewart, Vanessa Lisbeth Rubin, Jens J. Billgren
  • ANTI-PACAP ANTIBODIES AND USES THEREOF
    Publication number: 20160304604
    Abstract: The present invention is directed to antagonistic antibodies and antigen binding fragments thereof having binding specificity for PACAP. These antibodies inhibit, block or neutralize at least one biological effect associated with PACAP, e.g., vasodilation. In exemplary embodiments these antibodies and antigen binding fragments thereof may comprise specific VH, VL, and CDR polypeptides described herein. In some embodiments these antibodies and antigen binding fragments thereof bind to and/or compete for binding to specific epitope(s) on human PACAP. The invention is further directed to using these antagonistic anti-PACAP antibodies, and binding fragments thereof, for the diagnosis, assessment, and treatment of diseases and disorders associated with PACAP and conditions where antagonism of PACAP-related activities, such as vasodilation, mast cell degranulation, and/or neuronal activation, are therapeutically beneficial, e.g., headache and migraine indications.
    Type: Application
    Filed: April 15, 2016
    Publication date: October 20, 2016
    Inventors: Maria-Cristina LOOMIS, Leon F. Garcia-Martinez, Benjamin H. Dutzar, Daniel S. Allison, Lee Hendricks, Ethan W. Ojala, Pei Fan, Jeffrey T.L. Smith, John A. Latham, Charlie Karasek, Jenny Mulligan, Michelle Scalley-Kim, Erica Stewart, Vanessa Lisbeth Rubin, Jens J. Billgren
  • ANTI-ACTH ANTIBODIES AND USE THEREOF
    Publication number: 20150259414
    Abstract: The present invention is directed to antibodies and fragments thereof having binding specificity for ACTH. Another embodiment of this invention relates to the antibodies binding fragments thereof described herein, comprising the sequences of the VH, VL and/or CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-ACTH antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention further contemplates methods of making said anti-ACTH antibodies and binding fragments thereof.
    Type: Application
    Filed: February 20, 2015
    Publication date: September 17, 2015
    Inventors: Andrew Lawrence FELDHAUS, Leon GARCIA-MARTINEZ, Benjamin H. DUTZAR, Daniel S. ALLISON, Katie Olson ANDERSON, Ethan Wayne OJALA, Pei FAN, Charlie KARASEK, Jenny MULLIGAN, Michelle SCALLEY-KIM, Erica STEWART, Jeffrey T.L. SMITH, John LATHAM
  • Monomeric red fluorescent proteins
    Patent number: 7910714
    Abstract: Disclosed are sequences encoding monomeric variants of DsRed fluorescent proteins and methods of use.
    Type: Grant
    Filed: January 19, 2010
    Date of Patent: March 22, 2011
    Assignees: The University of Chicago, The University of Washington
    Inventors: Benjamin S. Glick, Brooke Bevis, Daniel E. Strongin, David Baker, Michelle Scalley-Kim
  • MONOMERIC RED FLUORESCENT PROTEINS
    Publication number: 20100184954
    Abstract: Disclosed are sequences encoding monomeric variants of DsRed fluorescent proteins and methods of use.
    Type: Application
    Filed: January 19, 2010
    Publication date: July 22, 2010
    Applicants: THE UNIVERSITY OF CHICAGO, THE UNIVERSITY OF WASHINGTON
    Inventors: Benjamin S. Glick, Brooke Bevis, Daniel E. Strongin, David Baker, Michelle Scalley-Kim
  • Monomeric red fluorescent proteins
    Patent number: 7671185
    Abstract: Disclosed are nucleotide sequences encoding monomeric variants of DsRed fluorescent proteins and methods of use thereof.
    Type: Grant
    Filed: May 15, 2007
    Date of Patent: March 2, 2010
    Assignees: The University of Chicago, The University of Washington
    Inventors: Benjamin S. Glick, Brooke Bevis, Daniel E. Strongin, David Baker, Michelle Scalley-Kim
  • MONOMERIC RED FLUORESCENT PROTEINS
    Publication number: 20070244298
    Abstract: Disclosed are sequences encoding monomeric variants of DsRed fluorescent proteins and methods of use.
    Type: Application
    Filed: May 15, 2007
    Publication date: October 18, 2007
    Applicants: THE UNIVERSITY OF CHICAGO, THE UNIVERSITY OF WASHINGTON
    Inventors: Benjamin Glick, Brooke Bevis, Daniel Strongin, David Baker, Michelle Scalley-Kim
  • Monomeric red fluorescent proteins
    Patent number: 7250298
    Abstract: Disclosed are sequences encoding monomeric variants of DsRed fluorescent proteins and methods of use.
    Type: Grant
    Filed: April 7, 2005
    Date of Patent: July 31, 2007
    Assignees: The University of Chicago, The University of Washington
    Inventors: Benjamin S. Glick, Brooke Bevis, Daniel E. Strongin, David Baker, Michelle Scalley-Kim
  • Monomeric red fluorescent proteins
    Publication number: 20060008878
    Abstract: Disclosed are sequences encoding monomeric variants of DsRed fluorescent proteins and methods of use.
    Type: Application
    Filed: April 7, 2005
    Publication date: January 12, 2006
    Applicants: The University of Chicago, The University of Washington
    Inventors: Benjamin Glick, Brooke Bevis, Daniel Strongin, David Baker, Michelle Scalley-Kim