Patents by Inventor Michelle Sparks

Michelle Sparks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOERODIBLE OCULAR DRUG DELIVERY INSERT AND THERAPEUTIC METHOD
    Publication number: 20220168142
    Abstract: This invention relates to implantable bioerodible inserts for delivering an active pharmaceutical ingredient to the eye. The invention also relates to methods of treatment using such inserts as well as methods of manufacturing such inserts.
    Type: Application
    Filed: February 14, 2022
    Publication date: June 2, 2022
    Inventors: Said SAIM, Michelle SPARKS, Dario PAGGIARINO, Basel KARZOUN
  • Abuse resistant opioid dosage form
    Publication number: 20060058331
    Abstract: The present invention pertains to a pharmaceutical dosage form comprising an opioid analgesic and a nontoxic N-methyl-D-aspartate receptor antagonist wherein the pharmaceutical dosage form is substantially free of an opioid antagonist The nontoxic N-methyl-D-aspartate receptor antagonist is present in an opioid euphoria-inhibiting amount to prevent or discourage abuse.
    Type: Application
    Filed: May 13, 2003
    Publication date: March 16, 2006
    Inventors: Bradley Galer, Huaihung Kao, Michelle Sparks, Yadi Zeng
  • Tocolytic oxytocin receptor antagonists
    Patent number: 6090805
    Abstract: This invention relates to certain novel benzoxazinone compounds and derivatives thereof, their synthesis, and their use as oxytocin receptor antagonists. One application of these compounds is in the treatment of preterm labor in mammals, especially humans. The ability of the compounds to relax uterine contractions in mammals also makes them useful for treating dysmenorrhea and stopping labor prior to cesarean delivery.
    Type: Grant
    Filed: June 10, 1998
    Date of Patent: July 18, 2000
    Assignee: Merck & Co., Inc.
    Inventors: Peter D. Williams, Michelle A. Sparks, Ian Bell, Debra S. Perlow, Kenneth Stauffer, Roger M. Freidinger
  • Piperazine oxytocin receptor antagonists
    Patent number: 5968938
    Abstract: This invention relates to certain novel piperazine compounds and derivatives thereof, their synthesis, and their use as oxytocin receptor antagonists. One application of these compounds is in the treatment of preterm labor in mammals, especially humans. The ability of the compounds to relax uterine contractions in mammals also makes them useful for treating dysmenorrhea and stopping labor prior to cesarean delivery.
    Type: Grant
    Filed: May 29, 1998
    Date of Patent: October 19, 1999
    Assignee: Merck & Co., Inc.
    Inventors: Peter D. Williams, Michelle A. Sparks, Ian Bell, James P. Guare, Jr., Roger M. Freidinger
  • Inhibitors of farnesyl-protein transferase
    Patent number: 5939439
    Abstract: The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
    Type: Grant
    Filed: December 22, 1997
    Date of Patent: August 17, 1999
    Assignee: Merck & Co., Inc.
    Inventors: Neville J. Anthony, Samuel L. Graham, Lekhanh O. Tran, Ian M. Bell, S. Jane deSolms, Robert P. Gomez, Michelle Sparks Kuo, William C. Lumma, Jr., Debra S. Perlow, Anthony W. Shaw, John S. Wai, Steven D. Young
  • Tocolytic oxytocin receptor antagonists
    Patent number: 5726172
    Abstract: This invention relates to certain novel benzoxazinone compounds and derivatives thereof, their synthesis, and their use as oxytocin receptor antagonists. One application of these compounds is in the treatment of preterm labor. The ability of the compounds to relax uterine contractions in mammals also makes them useful for treating dysmenorrhea and stopping labor prior to cesarean delivery.
    Type: Grant
    Filed: January 6, 1997
    Date of Patent: March 10, 1998
    Assignee: Merck & Co., Inc.
    Inventors: Michelle A. Sparks, Roger M. Freidinger, Debra S. Perlow, Peter D. Williams