Patents by Inventor Michelle Styles

Michelle Styles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystal structure and uses thereof
    Publication number: 20070276607
    Abstract: The present invention relates to X-ray crystallography studies of a JAK2 kinase domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.
    Type: Application
    Filed: January 4, 2007
    Publication date: November 29, 2007
    Inventors: Andrew Wilks, Christopher Burns, Emmanuelle Fantino, Isabelle Lucet, Jamie Rossjohn, Michelle Styles
  • Crystal structure and uses thereof
    Publication number: 20070136005
    Abstract: The present invention relates to X-ray crystallography studies of a JAK2 kinase domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.
    Type: Application
    Filed: January 4, 2007
    Publication date: June 14, 2007
    Inventors: Andrew Wilks, Christopher Burns, Emmanuelle Fantino, Isabelle Lucet, Jamie Rossjohn, Michelle Styles
  • Crystal structure and uses thereof
    Publication number: 20070136006
    Abstract: The present invention relates to X-ray crystallography studies of a JAK2 kinase domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.
    Type: Application
    Filed: January 4, 2007
    Publication date: June 14, 2007
    Inventors: Andrew Wilks, Christopher Burns, Emmanuelle Fantino, Isabelle Lucet, Jamie Rossjohn, Michelle Styles
  • Crystal structure and uses thereof
    Publication number: 20070129896
    Abstract: The present invention relates to X-ray crystallography studies of a JAK2 kinase domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.
    Type: Application
    Filed: January 4, 2007
    Publication date: June 7, 2007
    Inventors: Andrew Wilks, Christopher Burns, Emmanuelle Fantino, Isabelle Lucet, Jamie Rossjohn, Michelle Styles
  • Crystal structure and uses thereof
    Publication number: 20070129895
    Abstract: The present invention relates to X-ray crystallography studies of a JAK2 kinase domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.
    Type: Application
    Filed: January 4, 2007
    Publication date: June 7, 2007
    Inventors: Andrew Wilks, Christopher Burns, Emmanuelle Fantino, Isabelle Lucet, Jamie Rossjohn, Michelle Styles
  • Crystal structure and uses thereof
    Publication number: 20070128709
    Abstract: The present invention relates to X-ray crystallography studies of a human Janus Kinase 2 (JAK2) domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.
    Type: Application
    Filed: October 11, 2005
    Publication date: June 7, 2007
    Inventors: Andrew Wilks, Christopher Burns, Emmanuelle Fantino, Isabelle Lucet, Jamie Rossjohn, Michelle Styles