Patents by Inventor Michiel C. Heslinga

Michiel C. Heslinga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mesylates of piperazine derivatives and process for their preparation
    Patent number: 7030241
    Abstract: The invention relates to the mesylates of a group of piperazine derivatives and to a process for the preparation of these mesylates in an economic way in the high yield and of high purity. According to the process of the invention the synthesis of the piperazine ring and the mesylate formation are combined in a single reaction step.
    Type: Grant
    Filed: February 14, 2002
    Date of Patent: April 18, 2006
    Assignee: Solvay Pharmaceuticals B.V.
    Inventors: Marcel P. M. van Aar, Stefanus J. Schouten, Jan Zorgdrager, Michiel C. Heslinga
  • Process for the preparation of mesylates of peperazine derivatives
    Publication number: 20040077631
    Abstract: The invention relates to the mesylates of a group of piperazine derivatives and to a process for the preparation of these mesylates in an economic way in the high yield and of high purity. According to the process of the invention the synthesis of the piperazine ring and the mesylate formation are combined in a single reaction step. The invention relates to the mesylate of compounds of the formula (I) wherein X is a bicyclic heterocyclic phenyl group and Y is methyl, ethyl (optionally substituted with fluorine), cycloalkyl (3-7C) methyl, benzyl or m-phenyl benzyl.
    Type: Application
    Filed: August 15, 2003
    Publication date: April 22, 2004
    Inventors: Marcel P.M. van Aar, Stefanus J. Schouten, Jan Zorgdrager, Michiel C. Heslinga