Patents by Inventor Michiel Coenraad Bosch Van Oudtshoorn

Michiel Coenraad Bosch Van Oudtshoorn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical composition comprising diclofenac and cyclodextrin
    Patent number: 5679660
    Abstract: A method of preparing an injectable pharmaceutical or veterinary composition which comprises either diclofenac or a salt thereof and 2-hydroxypropyl beta-cyclodextrin, or an inclusion complex of diclofenac or a salt thereof and 2-hydroxypropyl beta-cyclodextrin, includes the step of dissolving either the diclofenac or salt thereof and the 2-hydroxypropyl beta-cyclodextrin, or the inclusion complex, in water to form a solution, the water having been acidified to a pH such that the pH of the solution is from 6.0 to 8.5 inclusive, in the absence of a phosphate buffer. The composition so produced has good stability on storage.
    Type: Grant
    Filed: December 2, 1994
    Date of Patent: October 21, 1997
    Assignee: Farmarc Nederland BV
    Inventors: Mark David Bodley, Lueta Ann Glintenkamp, Lawrence John Penkler, Michiel Coenraad Bosch van Oudtshoorn
  • Inclusion complex of beta-cyclodextrin and diclofenac, its preparation and use
    Patent number: 5674854
    Abstract: An inclusion complex of diclofenac, preferably as diclofenac sodium, and an unsubstituted beta-cyclodextrin has the formula 1 molecule of diclofenac to 1 molecule of the unsubstituted beta-cyclodextrin and preferably from 5 to 11 water molecules. The inclusion complex may be formulated as a pharmaceutical composition.
    Type: Grant
    Filed: October 7, 1994
    Date of Patent: October 7, 1997
    Assignee: Farmarc Nederland BV
    Inventors: Mark David Bodley, Mino Rodolfo Caira, Lueta Ann Glintenkamp, Vivienne Jean Griffith, Luigi Renzo Nassimbeni, Douglas George Murray Nicholson, Lawrence John Penkler, Michiel Coenraad Bosch Van Oudtshoorn