Patents by Inventor Michiel Elema

Michiel Elema has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Controlled agglomeration
    Publication number: 20070275074
    Abstract: A process for the preparation of a particulate material by a controlled agglomeration method, i.e. a method that enables a controlled growth in particle size. The method is especially suitable for use in the preparation of pharmaceutical compositions containing a therapeutically and/or prophylactically active substance which has a relatively low aqueous solubility and/or which is subject to chemical decomposition. The process comprising i) spraying a first composition comprising a carrier, which has a melting point of about 5° C. or more which is present in the first composition in liquid form, on a second composition comprising a material in solid form, the second composition having a temperature of at the most a temperature corresponding to the melting point of the carrier and/or the carrier composition and ii) mixing or others means of mechanical working the second composition onto which the first composition is sprayed to obtain the particulate material.
    Type: Application
    Filed: February 27, 2007
    Publication date: November 29, 2007
    Applicant: LifeCycle Pharma A/S
    Inventors: Per Holm, Anders Burr, Michiel Elema, Birgitte Mollgaard, Jannie Holm, Kirsten Schultz
  • Melt granulated composition and modified release dosage form prepared from said composition
    Publication number: 20060093668
    Abstract: Solid modified release dosage forms, prepared from melt granulated compositions comprising (A) one or more hydrophilic cellulose ether polymers, (B) a hydrophilic melt binder, and (C) a therapeutically active ingredient.
    Type: Application
    Filed: December 16, 2005
    Publication date: May 4, 2006
    Applicant: H. Lundbeck A/S
    Inventors: Michiel Elema, Per Holm
  • Crystalline composition containing escitalopram
    Publication number: 20050147674
    Abstract: Crystalline particles of escitalopram oxalate with a particle size of at least 40 ?m is disclosed. Method for the manufacture of said crystalline particles and pharmaceutical compositions comprising said crystalline particles are also disclosed.
    Type: Application
    Filed: February 7, 2005
    Publication date: July 7, 2005
    Inventors: Troels Christensen, Ken Liljegren, Michiel Elema, Lene Andresen, Shashank Mahashabde, Sebastian Assenza
  • Controlled agglomeration
    Publication number: 20050008706
    Abstract: A process for the preparation of a particulate material by a controlled agglomeration method, i.e. a method that enables a controlled growth in particle size. The method is especially suitable for use in the preparation of pharmaceutical compositions containing a therapeutically and/or prophylactically active substance which has a relatively low aqueous solubility and/or which is subject to chemical decomposition. The process comprising i) spraying a first composition comprising a carrier, which has a melting point of about 5° C. or more which is present in the first composition in liquid form, on a second composition comprising a material in solid form, the second composition having a temperature of at the most a temperature corresponding to the melting point of the carrier and/or the carrier composition and ii) mixing or others means of mechanical working the second composition onto which the first composition is sprayed to obtain the particulate material.
    Type: Application
    Filed: July 5, 2002
    Publication date: January 13, 2005
    Inventors: Per Holm, Anders Buur, Michiel Elema, Birgitte Mollgaard, Jannie Holm, Kirsten Schultz