Patents by Inventor Michiko Aihara

Michiko Aihara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROTEIN DIAGNOSTIC BIOMARKER FOR SEVERE DRUG ERUPTION
    Publication number: 20230146286
    Abstract: Biomarkers for diagnosing the disease activity, disease severity or disease type of severe cutaneous adverse drug reactions (SCARs) such as drug-induced hypersensitivity syndrome and Stevens-Johnson syndrome/toxic epidermal necrolysis are provided. Also provided is a method of testing SCARs, comprising measuring the expression of at least one protein selected from the group consisting of stratifin, TNF receptor superfamily member 8 (CD30/TNFRSF8), interleukin-1 receptor antagonist (IL-1Ra), and TNF receptor superfamily member 6B (DcR3/TNFRSF6B) in a sample derived from a subject.
    Type: Application
    Filed: April 15, 2021
    Publication date: May 11, 2023
    Applicants: JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF NATIONAL INSTITUTE OF HEALTH SCIENCES, TOSOH CORPORATION
    Inventors: Yoshiro SAITO, Ryosuke NAKAMURA, Noriaki ARAKAWA, Yasuo OHNO, Takashi IZUMI, Motonobu SATO, Takayoshi NISHIYA, Michiko AIHARA
  • Method for determining atopic dermatitis using protein marker
    Patent number: 7820396
    Abstract: It is an object of the present invention to find substances that can be used as disease markers for atopic dermatitis and the present invention provides a method for determining atopic dermatitis, including measurement of the expression of specific proteins and/or their genes in skin cells and/or skin tissues, wherein the specific proteins change their expression with inflammation caused by atopic dermatitis or change their expression according to the degree of predisposition to atopic dermatitis. The present invention also provides a kit for determining the degree of inflammation of atopic dermatitis or risk of developing atopic dermatitis, as well as a method for determining substances effective in the treatment and/or prevention of atopic dermatitis.
    Type: Grant
    Filed: October 19, 2006
    Date of Patent: October 26, 2010
    Assignees: Fancl Corporation
    Inventors: Satoshi Miyata, Kaoru Miyazaki, Chie Yasuda, Akihiro Iwamatsu, Zenro Ikezawa, Michiko Aihara, Kayano Moriyama
  • ATOPIC DERMATITIS MARKER AND TECHNIQUE OF USING THE SAME
    Publication number: 20090263792
    Abstract: It is an object of the present invention to find substances that can be used as disease markers for atopic dermatitis and the present invention provides a method for determining atopic dermatitis, including measurement of the expression of specific proteins and/or their genes in skin cells and/or skin tissues, wherein the specific proteins change their expression with inflammation caused by atopic dermatitis or change their expression according to the degree of predisposition to atopic dermatitis. The present invention also provides a kit for determining the degree of inflammation of atopic dermatitis or risk of developing atopic dermatitis, as well as a method for determining substances effective in the treatment and/or prevention of atopic dermatitis.
    Type: Application
    Filed: October 19, 2006
    Publication date: October 22, 2009
    Inventors: Satoshi Miyata, Kaoru Miyazaki, Chie Yasuda, Akihiro Iwamatsu, Zenro Ikezawa, Michiko Aihara, Kayano Moriyama