Patents by Inventor Michiko Fukuda

Michiko Fukuda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220280596
    Abstract: The present invention is a cytocidal agent including a peptide consisting of an amino acid sequence represented by SEQ ID NO: 1 and a site selectively binding to a target molecule, in which the peptide consisting of an amino acid sequence represented by SEQ ID NO: 1 is a peptide exclusively consisting of L-amino acids, a peptide in which, in amino acid sequences represented by SEQ ID NO: 1, the first to the 14th amino acids are D-amino acids, and the 15th to 19th amino acids are L-amino acids, a peptide in which, in amino acid sequences represented by SEQ ID NO: 1, the first to 14th amino acids are L-amino acids, and the 15th to the 19th amino acids are D-amino acids, or a peptide exclusively consisting of D-amino acids.
    Type: Application
    Filed: May 10, 2022
    Publication date: September 8, 2022
    Inventors: Kazuhiro SUGIHARA, Naohiro KANAYAMA, Yuichiro ONODERA, Toshiaki SHIBATA, Michiko FUKUDA, Motohiro NONAKA
  • Patent number: 11392475
    Abstract: A non-transitory computer-readable recording medium has stored therein a program that causes a computer to execute a process including: dividing a time from a start to an end of execution of a first job into a plurality of time periods, the time being represented in first power consumption information; calculating a cycle of a time-series variation of power consumption within each time period; generating, for each of the plurality of time periods, a prediction model for predicting power consumption of a predetermined future time; acquiring second power consumption information that is an actual measurement value of power consumption according to an elapsed time from a start of execution of a second job that is being executed; and predicting future power consumption of the second job, using the prediction model generated for a time period including the elapsed time from the start of execution of the second job to a present.
    Type: Grant
    Filed: January 24, 2020
    Date of Patent: July 19, 2022
    Assignee: FUJITSU LIMITED
    Inventors: Shigeto Suzuki, Michiko Shiraga, Koichi Shirahata, Hiroshi Endo, Hiroyuki Fukuda, Takuji Yamamoto
  • Patent number: 11385700
    Abstract: An apparatus calculates, based on attribute information of a new job and jobs that have been executed, a first similarity level of the attribute information between the new job and the jobs by using a calculation expression, identifies a job whose attribute information is most similar to that of the new job as a first candidate job, and estimates power consumption to be consumed by the new job at power consumption of the first candidate job. The apparatus calculates, for at least one of the jobs, a second similarity level of power consumption between the at least one of the jobs and the new job, identifies a job whose power consumption is most similar to that of the new job as a second candidate job, and adjusts the calculation expression to increase the first similarity level to be calculated between the new job and the second candidate job.
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: July 12, 2022
    Assignee: Fujitsu Limited
    Inventors: Shigeto Suzuki, Michiko Shiraga, Hiroshi Endo, Takashi Shiraishi, Yoshiyasu Doi, Hiroyuki Fukuda, Takuji Yamamoto
  • Patent number: 11357819
    Abstract: The present invention is a cytocidal agent including a peptide consisting of an amino acid sequence represented by SEQ ID NO: 1 and a site selectively binding to a target molecule, in which the peptide consisting of an amino acid sequence represented by SEQ ID NO: 1 is a peptide exclusively consisting of L-amino acids, a peptide in which, in amino acid sequences represented by SEQ ID NO: 1, the first to the 14th amino acids are D-amino acids, and the 15th to 19th amino acids are L-amino acids, a peptide in which, in amino acid sequences represented by SEQ ID NO: 1, the first to 14th amino acids are L-amino acids, and the 15th to the 19th amino acids are D-amino acids, or a peptide exclusively consisting of D-amino acids.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: June 14, 2022
    Assignee: FUJITA ACADEMY
    Inventors: Kazuhiro Sugihara, Naohiro Kanayama, Yuichiro Onodera, Toshiaki Shibata, Michiko Fukuda, Motohiro Nonaka
  • Publication number: 20210260202
    Abstract: Compositions and methods related to annexin 1-binding compounds. Also compositions comprising a moiety and a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Isolated nucleic acids comprising a nucleic acid sequence encoding a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Methods comprising administering to a subject a composition comprising a moiety and a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Methods of targeting a tumor cell in a subject comprising administering to the subject a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Methods of targeting a tumor cell in a subject comprising administering to the subject a composition comprising a moiety and a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell.
    Type: Application
    Filed: April 26, 2021
    Publication date: August 26, 2021
    Inventors: Michiko Fukuda, Kazuhiro Sugihara, Naohira Kanayama
  • Publication number: 20200323943
    Abstract: The present invention provides a peptide comprising the amino acid sequence of any of the formulas (I)-(III) below: (I) an amino acid sequence of (X1) [D] P [D] (X2) [D] wherein X1 is W or F, X2 is S or T, and each amino acid symbol immediately followed by symbol [D] is a D form of the amino acid, (II) an amino acid sequence of P[D]T[D] (X)n F[D] wherein (X)n is any amino acid in the number of n selected independently of each other, n is an integer of 0-4, and the symbol [D] is as defined above, (III) an amino acid sequence that is a Retro-inverso of the amino acid sequence of any of the aforementioned (I) and the aforementioned (II); and a conjugate containing the peptide and a functional part.
    Type: Application
    Filed: June 25, 2020
    Publication date: October 15, 2020
    Applicant: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Michiko FUKUDA, Motohiro NONAKA
  • Publication number: 20200289608
    Abstract: The present invention is a cytocidal agent including a peptide consisting of an amino acid sequence represented by SEQ ID NO: 1 and a site selectively binding to a target molecule, in which the peptide consisting of an amino acid sequence represented by SEQ ID NO: 1 is a peptide exclusively consisting of L-amino acids, a peptide in which, in amino acid sequences represented by SEQ ID NO: 1, the first to the 14 amino acids are D-amino acids, and the 15th to 19th amino acids are L-amino acids, a peptide in which, in amino acid sequences represented by SEQ ID NO: 1, the first to 14th amino acids are L-amino acids, and the 15th to the 1.9th amino acids are D-amino acids, or a peptide exclusively consisting of D-amino acids.
    Type: Application
    Filed: August 23, 2018
    Publication date: September 17, 2020
    Inventors: Kazuhiro SUGIHARA, Naohiro KANAYAMA, Yuichiro ONODERA, Toshiaki SHIBATA, Michiko FUKUDA, Motohiro NONAKA
  • Patent number: 10695396
    Abstract: The present invention provides a peptide comprising the amino acid sequence of any of the formulas (I)-(III) below: (I) an amino acid sequence of (X1)[D]P[D](X2)[D] wherein X1 is W or F, X2 is S or T, and each amino acid symbol immediately followed by symbol [D] is a D form of the amino acid, (II) an amino acid sequence of P[D]T[D](X)n F[D] wherein (X)n is any amino acid in the number of n selected independently of each other, n is an integer of 0-4, and the symbol [D] is as defined above, (III) an amino acid sequence that is a Retro-inverso of the amino acid sequence of any of the aforementioned (I) and the aforementioned (II); and a conjugate containing the peptide and a functional part.
    Type: Grant
    Filed: August 16, 2017
    Date of Patent: June 30, 2020
    Assignee: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Michiko Fukuda, Motohiro Nonaka
  • Publication number: 20200030452
    Abstract: A synthetic process for manufacture of a tumor-vascular targeting antitumor agent wherein the antitumor agent comprises an annexin-1 binding peptide conjugated to an anticancer drug through a linker. An efficient, practical, reproducible and scalable process for the manufacturing of a tumor-vascular targeting antitumor agent wherein the antitumor agent comprises an annexin-1 binding peptide conjugated to an anticancer drug through a linker with high purity and yield.
    Type: Application
    Filed: October 2, 2017
    Publication date: January 30, 2020
    Inventors: Jalal Haddad, Michiko Fukuda
  • Publication number: 20190175684
    Abstract: The present invention provides a peptide comprising the amino acid sequence of any of the formulas (I-(III) below: (I) an amino acid sequence of (X1)[D]P[D](X2)[D] wherein X1 is W or F, X2 is S or T, and each amino acid symbol immediately followed by symbol [D] is a D form of the amino acid, (II) an amino acid sequence of P[D]T[D](X)n F[D] wherein (X)n is any amino acid in the number of n selected independently of each other, n is an integer of 0-4, and the symbol [D] is as defined above, (III) an amino acid sequence that is a Retro-inverso of the amino acid sequence of any of the aforementioned (I) and the aforementioned (II); and a conjugate containing the peptide and a functional part.
    Type: Application
    Filed: August 16, 2017
    Publication date: June 13, 2019
    Applicant: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Michiko FUKUDA, Motohiro NONAKA
  • Patent number: 10259844
    Abstract: Provided herein are compositions and methods for selectively targeting an endometriosis cell.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: April 16, 2019
    Assignee: Sanford-Burnham Medical Research Institute
    Inventors: Michiko Fukuda, Daisuke Aoki, Shiro Nozawa
  • Patent number: 9943333
    Abstract: The present invention relates to an agent for activating mammalian sperm and a method for activating sperm by use of the activating agent. More specifically, the present invention relates to a sperm activating agent containing endo-?-galactosidase and/or FGF, which accelerate motility of mammalian sperm, for use in in-vitro fertilization and artificial insemination by husband and a sperm activating method by adding endo-?-galactosidase and/or FGF.
    Type: Grant
    Filed: September 19, 2013
    Date of Patent: April 17, 2018
    Assignees: NATIONAL UNIVERSITY CORPORATION, HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Kazuhiro Sugihara, Michiko Fukuda
  • Publication number: 20170326245
    Abstract: Compositions and methods related to annexin 1-binding compounds. Also compositions comprising a moiety and a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Isolated nucleic acids comprising a nucleic acid sequence encoding a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Methods comprising administering to a subject a composition comprising a moiety and a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Methods of targeting a tumor cell in a subject comprising administering to the subject a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Methods of targeting a tumor cell in a subject comprising administering to the subject a composition comprising a moiety and a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell.
    Type: Application
    Filed: April 4, 2017
    Publication date: November 16, 2017
    Inventors: Michiko Fukuda, Kazuhiro Sugihara, Naohira Kanayama
  • Patent number: 9783576
    Abstract: Disclosed are compositions and methods for selectively targeting an endometriosis cell. Also disclosed are compositions and methods for treating endometriosis.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: October 10, 2017
    Assignee: Sanford-Burnham Medical Research Institute
    Inventors: Michiko Fukuda, Kazuhiro Sugihara
  • Patent number: 9610359
    Abstract: Disclosed are conjugates comprising the annexin 1-binding peptide IFLLWQR covalently linked to a therapeutic or detectable agent. Also disclosed are compositions comprising a moiety and a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Also disclosed are isolated nucleic acids comprising a nucleic acid sequence encoding a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Also disclosed are methods comprising administering to a subject a composition comprising a moiety and a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Also disclosed are methods of targeting a tumor cell in a subject comprising administering to the subject a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell.
    Type: Grant
    Filed: December 23, 2010
    Date of Patent: April 4, 2017
    Assignees: Burnham Institute for Medical Research, Hamamatsu University School of Medicine
    Inventors: Michiko Fukuda, Kazuhiro Sugihara, Naohira Kanayama
  • Publication number: 20160145308
    Abstract: Disclosed are compositions and methods for selectively targeting an endometriosis cell. Also disclosed are compositions and methods for treating endometriosis.
    Type: Application
    Filed: June 11, 2014
    Publication date: May 26, 2016
    Inventors: Michiko FUKUDA, Kazuhiro SUGIHARA
  • Publication number: 20150245852
    Abstract: The present invention relates to an agent for activating mammalian sperm and a method for activating sperm by use of the activating agent. More specifically, the present invention relates to a sperm activating agent containing endo-?-galactosidase and/or FGF, which accelerate motility of mammalian sperm, for use in in-vitro fertilization and artificial insemination by husband and a sperm activating method by adding endo-?-galactosidase and/or FGF.
    Type: Application
    Filed: September 19, 2013
    Publication date: September 3, 2015
    Applicant: National University Corporation Hamamatsu University School of Medicine
    Inventors: Kazuhiro Sugihara, Michiko Fukuda
  • Patent number: 9006404
    Abstract: Provided herein are compositions and methods for selectively targeting an endometriosis cell.
    Type: Grant
    Filed: December 26, 2006
    Date of Patent: April 14, 2015
    Assignees: Sanford-Burnham Medical Research Institute, Keio University
    Inventors: Michiko Fukuda, Daisuke Aoki, Noriko Nozawa
  • Publication number: 20120251453
    Abstract: Disclosed are conjugates comprising the annexin 1-binding peptide IFLLWQR covalently linked to a therapeutic or detectable agent. Also disclosed are compositions comprising a moiety and a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Also disclosed are isolated nucleic acids comprising a nucleic acid sequence encoding a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Also disclosed are methods comprising administering to a subject a composition comprising a moiety and a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Also disclosed are methods of targeting a tumor cell in a subject comprising administering to the subject a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell.
    Type: Application
    Filed: December 23, 2010
    Publication date: October 4, 2012
    Inventors: Michiko Fukuda, Kazuhiro Sugihara, Naohira Kanayama
  • Patent number: 8097588
    Abstract: Disclosed herein are compositions and methods useful for promoting sperm motility, promoting embryonic stem cell formation, promoting trophoblast formation, or promoting neuronal growth. The compositions and methods are based on peptide sequences that bind trophinin, inhibit bystin-mediated arrest of epidermal growth factor (EGF) receptor, and promotes EGF receptor autophosphorylation.
    Type: Grant
    Filed: February 6, 2008
    Date of Patent: January 17, 2012
    Assignee: Sanford-Burnham Medical Research Institute
    Inventor: Michiko Fukuda