Patents by Inventor Michiko Miura
Michiko Miura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8673265Abstract: The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity carborane-containing porphyrin compounds with halide, amine, or nitro groups and methods for their use particularly in boron neutron capture therapy (BNCT), X-ray radiation therapy (XRT), and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these carborane-containing porphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.Type: GrantFiled: September 10, 2012Date of Patent: March 18, 2014Assignee: Brookhaven Science Associates, LLCInventors: Michiko Miura, Mark W. Renner
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Patent number: 8444953Abstract: The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity halogenated, carborane-containing 5,10,15,20-tetraphenylporphyrin compounds and methods for their use particularly in boron neutron capture therapy (BNCT) and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these halogenated, carborane-containing tetraphenylporphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.Type: GrantFiled: March 22, 2007Date of Patent: May 21, 2013Assignee: Brookhaven Science Associates, LLCInventors: Michiko Miura, Haitao Wu
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Publication number: 20130004419Abstract: The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity carborane-containing porphyrin compounds with halide, amine, or nitro groups and methods for their use particularly in boron neutron capture therapy (BNCT), X-ray radiation therapy (XRT), and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these carborane-containing porphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.Type: ApplicationFiled: September 10, 2012Publication date: January 3, 2013Applicant: Brookhaven Science Associates, LLCInventors: Michiko Miura, Mark W. Renner
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Patent number: 8287839Abstract: The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity carborane-containing porphyrin compounds with halide, amine, or nitro groups and methods for their use particularly in boron neutron capture therapy (BNCT), X-ray radiation therapy (XRT), and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these carborane-containing porphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.Type: GrantFiled: December 4, 2006Date of Patent: October 16, 2012Assignee: Brookhaven Science Associates, LLCInventors: Michiko Miura, Mark W. Renner
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Patent number: 8213560Abstract: Disclosed herein is a phase-locked loop circuit including: a voltage controlled oscillator; a variable frequency divider circuit for frequency-dividing an oscillating signal of the voltage controlled oscillator into a 1/N (N is an integer) frequency; a phase comparator circuit for comparing phases of a frequency-divided signal and a reference signal of a reference frequency with each other; a charge pump circuit for outputting a charge pump current changed in pulse width; a loop filter for being supplied with the charge pump current and outputting a direct-current voltage changed in level; and a control circuit for calculating a value of the charge pump current as a function of the oscillating frequency of the voltage controlled oscillator and a coefficient for setting a phase locked loop band, and setting the value of the charge pump current in the charge pump circuit.Type: GrantFiled: March 16, 2009Date of Patent: July 3, 2012Assignee: Sony CorporationInventors: Kiyoshi Miura, Michiko Miura, legal representative
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Patent number: 8185076Abstract: Disclosed herein is a radio receiver including: an oscillator circuit including a phase-locked circuit and a voltage-controlled oscillator circuit; a first frequency divider circuit; a frequency converter circuit; a signal adding circuit; a test signal generating circuit including at least one second frequency divider circuit; and a controlling section configured to set frequency dividing factors.Type: GrantFiled: October 21, 2009Date of Patent: May 22, 2012Assignee: Sony CorporationInventors: Kiyoshi Miura, Michiko Miura, legal representative
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Patent number: 8121578Abstract: An electronic apparatus includes: a first integrated circuit including an internal component section, a nonvolatile memory, and an interface section; a test signal generation section configured to generate a test signal to be supplied to the first integrated circuit; a second integrated circuit including a processing section configured to process an output signal of the first integrated circuit, a signal processor to which the interface section of the first integrated circuit is connected and a detection section configured to detect decision information for deciding a result of the process of the test signal carried out by the processing section; and a control section configured to supply the test signal from the test signal generation section in place of the input signal to the first integrated circuit and issuing an instruction to the signal processor of the second integrated circuit to produce actual use adjustment data.Type: GrantFiled: March 19, 2009Date of Patent: February 21, 2012Assignee: Sony CorporationInventors: Takahiro Okada, Kiyoshi Miura, Michiko Miura, legal representative, Naruhiro Yoshida
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Patent number: 7965144Abstract: The present invention provides a phase locked loop circuit including: a voltage controlled oscillator; a variable frequency-dividing circuit; a phase comparing circuit for comparing a phase of the frequency-dividing signal a charge pump circuit; a loop filter; a voltage supplying circuit; a frequency measuring circuit; and a voltage measuring circuit.Type: GrantFiled: March 16, 2009Date of Patent: June 21, 2011Assignee: Sony CorporationInventors: Kiyoshi Miura, Michiko Miura, legal representative
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Publication number: 20100097531Abstract: Disclosed herein is a radio receiver including: an oscillator circuit including a phase-locked circuit and a voltage-controlled oscillator circuit; a first frequency divider circuit; a frequency converter circuit; a signal adding circuit; a test signal generating circuit including at least one second frequency divider circuit; and a controlling section configured to set frequency dividing factors.Type: ApplicationFiled: October 21, 2009Publication date: April 22, 2010Inventors: Kiyoshi MIURA, Michiko Miura
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Publication number: 20090245450Abstract: Disclosed herein is a phase-locked loop circuit including: a voltage controlled oscillator; a variable frequency divider circuit for frequency-dividing an oscillating signal of the voltage controlled oscillator into a 1/N (N is an integer) frequency; a phase comparator circuit for comparing phases of a frequency-divided signal and a reference signal of a reference frequency with each other; a charge pump circuit for outputting a charge pump current changed in pulse width; a loop filter for being supplied with the charge pump current and outputting a direct-current voltage changed in level; and a control circuit for calculating a value of the charge pump current as a function of the oscillating frequency of the voltage controlled oscillator and a coefficient for setting a phase locked loop band, and setting the value of the charge pump current in the charge pump circuit.Type: ApplicationFiled: March 16, 2009Publication date: October 1, 2009Applicant: Sony CorporationInventors: Kiyoshi Miura, Michiko Miura
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Publication number: 20090243736Abstract: The present invention provides a phase locked loop circuit including: a voltage controlled oscillator; a variable frequency-dividing circuit; a phase comparing circuit for comparing a phase of the frequency-dividing signal a charge pump circuit; a loop filter; a voltage supplying circuit; a frequency measuring circuit; and a voltage measuring circuit.Type: ApplicationFiled: March 16, 2009Publication date: October 1, 2009Applicant: Sony CorporationInventors: Kiyoshi Miura, Michiko Miura
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Publication number: 20090244401Abstract: An electronic apparatus includes: a first integrated circuit including an internal component section, a nonvolatile memory, and an interface section; a test signal generation section configured to generate a test signal to be supplied to the first integrated circuit; a second integrated circuit including a processing section configured to process an output signal of the first integrated circuit, a signal processor to which the interface section of the first integrated circuit is connected and a detection section configured to detect decision information for deciding a result of the process of the test signal carried out by the processing section; and a control section configured to supply the test signal from the test signal generation section in place of the input signal to the first integrated circuit and issuing an instruction to the signal processor of the second integrated circuit to produce actual use adjustment data;Type: ApplicationFiled: March 19, 2009Publication date: October 1, 2009Applicant: Sony CorporationInventors: Takahiro OKADA, Kiyoshi MIURA, Michiko MIURA, Naruhiko YOSHIDA
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Patent number: 7533356Abstract: A parameter adjusting device and a parameter adjusting method configured to adjust a great number of parameters used for a circuit design model of a semiconductor element such as a transistor within a short time. A parameter adjusting device adapts a circuit design model wherein a formula for analysis is derived based on a surface potential such as, for example, the HiSIM, as the circuit design model of a semiconductor element; defines a chromosome wherein a respective great number of parameters of the model are genes; and optimizes the parameter based on property measured data of a tested element, using a genetic algorithm. Parameter adjustment comprises a first step adjusting the parameters which determine the structure of the semiconductor element based on the property measured data of a long channel group; and a second step adjusting nonadjusted parameters based on the property measured data of various lengths of channels with reference to a result of the first step.Type: GrantFiled: March 29, 2005Date of Patent: May 12, 2009Assignee: Evolvable Systems Research Institute Inc.Inventors: Masahiro Murakawa, Keiichi Ito, Michiko Miura
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Publication number: 20080279781Abstract: The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity glycosylated carborane-containing 5,10,15,20-tetraphenylporphyrin compounds and methods for their use particularly in boron neutron capture therapy (BNCT) and photodynamic therapy (PDT) for the treatment of tumors of the brain, and head and neck. The invention is also directed to using these glycosylated carborane-containing tetraphenylporphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.Type: ApplicationFiled: May 10, 2007Publication date: November 13, 2008Applicant: Brookhaven Science Associates, LLCInventors: Michiko Miura, Haitao Wu
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Publication number: 20080233047Abstract: The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity halogenated, carborane-containing 5,10,15,20-tetraphenylporphyrin compounds and methods for their use particularly in boron neutron capture therapy (BNCT) and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these halogenated, carborane-containing tetraphenylporphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.Type: ApplicationFiled: March 22, 2007Publication date: September 25, 2008Applicant: Brookhaven Science Associates, LLCInventors: Michiko Miura, Haitao Wu
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Publication number: 20080131376Abstract: The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity carborane-containing porphyrin compounds with halide, amine, or nitro groups and methods for their use particularly in boron neutron capture therapy (BNCT), X-ray radiation therapy (XRT), and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these carborane-containing porphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.Type: ApplicationFiled: December 4, 2006Publication date: June 5, 2008Applicant: Brookhaven Science Associates, LLCInventors: Michiko Miura, Mark W. Renner
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Publication number: 20070198103Abstract: A parameter adjusting device and a parameter adjusting method configured to adjust a great number of parameters used for a circuit design model of a semiconductor element such as a transistor within a short time. A parameter adjusting device adapts a circuit design model wherein a formula for analysis is derived based on a surface potential such as, for example, the HiSIM, as the circuit design model of a semiconductor element; defines a chromosome wherein a respective great number of parameters of the model are genes; and optimizes the parameter based on property measured data of a tested element, using a genetic algorithm. Parameter adjustment comprises a first step adjusting the parameters which determine the structure of the semiconductor element based on the property measured data of a long channel group; and a second step adjusting nonadjusted parameters based on the property measured data of various lengths of channels with reference to a result of the first step.Type: ApplicationFiled: March 29, 2005Publication date: August 23, 2007Applicant: EVOLVABLE SYSTEMS RESEARCH INSTITUTE INC.Inventors: Masahiro Murakawa, Keiichi Ito, Michiko Miura
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Publication number: 20070093463Abstract: Low toxicity halogenated carborane-containing tetraphenylporphyrin compounds and methods for their use particularly in boron neutron capture therapy (BNCT), X-ray radiation therapy (XRT) and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention also includes methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET using these halogenated carborane-containing tetraphenylporphyrin compounds.Type: ApplicationFiled: December 1, 2006Publication date: April 26, 2007Applicant: Brookhaven Science Associates, LLCInventors: Michiko Miura, Haitao Wu
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Patent number: 7096129Abstract: A threshold voltage model with an impurity concentration profile in a channel direction taken into account is provided in the pocket implant MOSFET. With penetration length of the implanted pocket in the channel direction and the maximum impurity concentration of the implant pocket used as physical parameters, the threshold voltage model is obtained by linearly approximating the profile in the channel direction. By analytically solving the model by using a new threshold condition with inhomogeneous profile taken into account, the threshold voltage can be accurately obtained. Based on thus obtained model, the threshold voltage can be predicted and can be used for circuit design.Type: GrantFiled: August 25, 2004Date of Patent: August 22, 2006Assignee: Semiconductor Technology Academic Research CenterInventors: Daisuke Kitamaru, Michiko Miura
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Patent number: 6995260Abstract: The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity carborane-containing 5, 10, 15, 20-tetraphenylporphyrin compounds and methods for their use particularly in boron neutron capture therapy (BNCT) and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these carborane-containing tetraphenyl porphyrin compounds to methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.Type: GrantFiled: May 20, 2004Date of Patent: February 7, 2006Assignee: Brookhaven Science Associates, LLCInventors: Haitao Wu, Michiko Miura