Patents by Inventor Michiko Miura

Michiko Miura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8673265
    Abstract: The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity carborane-containing porphyrin compounds with halide, amine, or nitro groups and methods for their use particularly in boron neutron capture therapy (BNCT), X-ray radiation therapy (XRT), and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these carborane-containing porphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.
    Type: Grant
    Filed: September 10, 2012
    Date of Patent: March 18, 2014
    Assignee: Brookhaven Science Associates, LLC
    Inventors: Michiko Miura, Mark W. Renner
  • Patent number: 8444953
    Abstract: The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity halogenated, carborane-containing 5,10,15,20-tetraphenylporphyrin compounds and methods for their use particularly in boron neutron capture therapy (BNCT) and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these halogenated, carborane-containing tetraphenylporphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.
    Type: Grant
    Filed: March 22, 2007
    Date of Patent: May 21, 2013
    Assignee: Brookhaven Science Associates, LLC
    Inventors: Michiko Miura, Haitao Wu
  • Publication number: 20130004419
    Abstract: The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity carborane-containing porphyrin compounds with halide, amine, or nitro groups and methods for their use particularly in boron neutron capture therapy (BNCT), X-ray radiation therapy (XRT), and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these carborane-containing porphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.
    Type: Application
    Filed: September 10, 2012
    Publication date: January 3, 2013
    Applicant: Brookhaven Science Associates, LLC
    Inventors: Michiko Miura, Mark W. Renner
  • Patent number: 8287839
    Abstract: The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity carborane-containing porphyrin compounds with halide, amine, or nitro groups and methods for their use particularly in boron neutron capture therapy (BNCT), X-ray radiation therapy (XRT), and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these carborane-containing porphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.
    Type: Grant
    Filed: December 4, 2006
    Date of Patent: October 16, 2012
    Assignee: Brookhaven Science Associates, LLC
    Inventors: Michiko Miura, Mark W. Renner
  • Patent number: 8213560
    Abstract: Disclosed herein is a phase-locked loop circuit including: a voltage controlled oscillator; a variable frequency divider circuit for frequency-dividing an oscillating signal of the voltage controlled oscillator into a 1/N (N is an integer) frequency; a phase comparator circuit for comparing phases of a frequency-divided signal and a reference signal of a reference frequency with each other; a charge pump circuit for outputting a charge pump current changed in pulse width; a loop filter for being supplied with the charge pump current and outputting a direct-current voltage changed in level; and a control circuit for calculating a value of the charge pump current as a function of the oscillating frequency of the voltage controlled oscillator and a coefficient for setting a phase locked loop band, and setting the value of the charge pump current in the charge pump circuit.
    Type: Grant
    Filed: March 16, 2009
    Date of Patent: July 3, 2012
    Assignee: Sony Corporation
    Inventors: Kiyoshi Miura, Michiko Miura, legal representative
  • Patent number: 8185076
    Abstract: Disclosed herein is a radio receiver including: an oscillator circuit including a phase-locked circuit and a voltage-controlled oscillator circuit; a first frequency divider circuit; a frequency converter circuit; a signal adding circuit; a test signal generating circuit including at least one second frequency divider circuit; and a controlling section configured to set frequency dividing factors.
    Type: Grant
    Filed: October 21, 2009
    Date of Patent: May 22, 2012
    Assignee: Sony Corporation
    Inventors: Kiyoshi Miura, Michiko Miura, legal representative
  • Patent number: 8121578
    Abstract: An electronic apparatus includes: a first integrated circuit including an internal component section, a nonvolatile memory, and an interface section; a test signal generation section configured to generate a test signal to be supplied to the first integrated circuit; a second integrated circuit including a processing section configured to process an output signal of the first integrated circuit, a signal processor to which the interface section of the first integrated circuit is connected and a detection section configured to detect decision information for deciding a result of the process of the test signal carried out by the processing section; and a control section configured to supply the test signal from the test signal generation section in place of the input signal to the first integrated circuit and issuing an instruction to the signal processor of the second integrated circuit to produce actual use adjustment data.
    Type: Grant
    Filed: March 19, 2009
    Date of Patent: February 21, 2012
    Assignee: Sony Corporation
    Inventors: Takahiro Okada, Kiyoshi Miura, Michiko Miura, legal representative, Naruhiro Yoshida
  • Patent number: 7965144
    Abstract: The present invention provides a phase locked loop circuit including: a voltage controlled oscillator; a variable frequency-dividing circuit; a phase comparing circuit for comparing a phase of the frequency-dividing signal a charge pump circuit; a loop filter; a voltage supplying circuit; a frequency measuring circuit; and a voltage measuring circuit.
    Type: Grant
    Filed: March 16, 2009
    Date of Patent: June 21, 2011
    Assignee: Sony Corporation
    Inventors: Kiyoshi Miura, Michiko Miura, legal representative
  • Publication number: 20100097531
    Abstract: Disclosed herein is a radio receiver including: an oscillator circuit including a phase-locked circuit and a voltage-controlled oscillator circuit; a first frequency divider circuit; a frequency converter circuit; a signal adding circuit; a test signal generating circuit including at least one second frequency divider circuit; and a controlling section configured to set frequency dividing factors.
    Type: Application
    Filed: October 21, 2009
    Publication date: April 22, 2010
    Inventors: Kiyoshi MIURA, Michiko Miura
  • Publication number: 20090245450
    Abstract: Disclosed herein is a phase-locked loop circuit including: a voltage controlled oscillator; a variable frequency divider circuit for frequency-dividing an oscillating signal of the voltage controlled oscillator into a 1/N (N is an integer) frequency; a phase comparator circuit for comparing phases of a frequency-divided signal and a reference signal of a reference frequency with each other; a charge pump circuit for outputting a charge pump current changed in pulse width; a loop filter for being supplied with the charge pump current and outputting a direct-current voltage changed in level; and a control circuit for calculating a value of the charge pump current as a function of the oscillating frequency of the voltage controlled oscillator and a coefficient for setting a phase locked loop band, and setting the value of the charge pump current in the charge pump circuit.
    Type: Application
    Filed: March 16, 2009
    Publication date: October 1, 2009
    Applicant: Sony Corporation
    Inventors: Kiyoshi Miura, Michiko Miura
  • Publication number: 20090243736
    Abstract: The present invention provides a phase locked loop circuit including: a voltage controlled oscillator; a variable frequency-dividing circuit; a phase comparing circuit for comparing a phase of the frequency-dividing signal a charge pump circuit; a loop filter; a voltage supplying circuit; a frequency measuring circuit; and a voltage measuring circuit.
    Type: Application
    Filed: March 16, 2009
    Publication date: October 1, 2009
    Applicant: Sony Corporation
    Inventors: Kiyoshi Miura, Michiko Miura
  • Publication number: 20090244401
    Abstract: An electronic apparatus includes: a first integrated circuit including an internal component section, a nonvolatile memory, and an interface section; a test signal generation section configured to generate a test signal to be supplied to the first integrated circuit; a second integrated circuit including a processing section configured to process an output signal of the first integrated circuit, a signal processor to which the interface section of the first integrated circuit is connected and a detection section configured to detect decision information for deciding a result of the process of the test signal carried out by the processing section; and a control section configured to supply the test signal from the test signal generation section in place of the input signal to the first integrated circuit and issuing an instruction to the signal processor of the second integrated circuit to produce actual use adjustment data;
    Type: Application
    Filed: March 19, 2009
    Publication date: October 1, 2009
    Applicant: Sony Corporation
    Inventors: Takahiro OKADA, Kiyoshi MIURA, Michiko MIURA, Naruhiko YOSHIDA
  • Patent number: 7533356
    Abstract: A parameter adjusting device and a parameter adjusting method configured to adjust a great number of parameters used for a circuit design model of a semiconductor element such as a transistor within a short time. A parameter adjusting device adapts a circuit design model wherein a formula for analysis is derived based on a surface potential such as, for example, the HiSIM, as the circuit design model of a semiconductor element; defines a chromosome wherein a respective great number of parameters of the model are genes; and optimizes the parameter based on property measured data of a tested element, using a genetic algorithm. Parameter adjustment comprises a first step adjusting the parameters which determine the structure of the semiconductor element based on the property measured data of a long channel group; and a second step adjusting nonadjusted parameters based on the property measured data of various lengths of channels with reference to a result of the first step.
    Type: Grant
    Filed: March 29, 2005
    Date of Patent: May 12, 2009
    Assignee: Evolvable Systems Research Institute Inc.
    Inventors: Masahiro Murakawa, Keiichi Ito, Michiko Miura
  • Publication number: 20080279781
    Abstract: The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity glycosylated carborane-containing 5,10,15,20-tetraphenylporphyrin compounds and methods for their use particularly in boron neutron capture therapy (BNCT) and photodynamic therapy (PDT) for the treatment of tumors of the brain, and head and neck. The invention is also directed to using these glycosylated carborane-containing tetraphenylporphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.
    Type: Application
    Filed: May 10, 2007
    Publication date: November 13, 2008
    Applicant: Brookhaven Science Associates, LLC
    Inventors: Michiko Miura, Haitao Wu
  • Publication number: 20080233047
    Abstract: The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity halogenated, carborane-containing 5,10,15,20-tetraphenylporphyrin compounds and methods for their use particularly in boron neutron capture therapy (BNCT) and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these halogenated, carborane-containing tetraphenylporphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.
    Type: Application
    Filed: March 22, 2007
    Publication date: September 25, 2008
    Applicant: Brookhaven Science Associates, LLC
    Inventors: Michiko Miura, Haitao Wu
  • Publication number: 20080131376
    Abstract: The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity carborane-containing porphyrin compounds with halide, amine, or nitro groups and methods for their use particularly in boron neutron capture therapy (BNCT), X-ray radiation therapy (XRT), and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these carborane-containing porphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.
    Type: Application
    Filed: December 4, 2006
    Publication date: June 5, 2008
    Applicant: Brookhaven Science Associates, LLC
    Inventors: Michiko Miura, Mark W. Renner
  • Publication number: 20070198103
    Abstract: A parameter adjusting device and a parameter adjusting method configured to adjust a great number of parameters used for a circuit design model of a semiconductor element such as a transistor within a short time. A parameter adjusting device adapts a circuit design model wherein a formula for analysis is derived based on a surface potential such as, for example, the HiSIM, as the circuit design model of a semiconductor element; defines a chromosome wherein a respective great number of parameters of the model are genes; and optimizes the parameter based on property measured data of a tested element, using a genetic algorithm. Parameter adjustment comprises a first step adjusting the parameters which determine the structure of the semiconductor element based on the property measured data of a long channel group; and a second step adjusting nonadjusted parameters based on the property measured data of various lengths of channels with reference to a result of the first step.
    Type: Application
    Filed: March 29, 2005
    Publication date: August 23, 2007
    Applicant: EVOLVABLE SYSTEMS RESEARCH INSTITUTE INC.
    Inventors: Masahiro Murakawa, Keiichi Ito, Michiko Miura
  • Publication number: 20070093463
    Abstract: Low toxicity halogenated carborane-containing tetraphenylporphyrin compounds and methods for their use particularly in boron neutron capture therapy (BNCT), X-ray radiation therapy (XRT) and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention also includes methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET using these halogenated carborane-containing tetraphenylporphyrin compounds.
    Type: Application
    Filed: December 1, 2006
    Publication date: April 26, 2007
    Applicant: Brookhaven Science Associates, LLC
    Inventors: Michiko Miura, Haitao Wu
  • Patent number: 7096129
    Abstract: A threshold voltage model with an impurity concentration profile in a channel direction taken into account is provided in the pocket implant MOSFET. With penetration length of the implanted pocket in the channel direction and the maximum impurity concentration of the implant pocket used as physical parameters, the threshold voltage model is obtained by linearly approximating the profile in the channel direction. By analytically solving the model by using a new threshold condition with inhomogeneous profile taken into account, the threshold voltage can be accurately obtained. Based on thus obtained model, the threshold voltage can be predicted and can be used for circuit design.
    Type: Grant
    Filed: August 25, 2004
    Date of Patent: August 22, 2006
    Assignee: Semiconductor Technology Academic Research Center
    Inventors: Daisuke Kitamaru, Michiko Miura
  • Patent number: 6995260
    Abstract: The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity carborane-containing 5, 10, 15, 20-tetraphenylporphyrin compounds and methods for their use particularly in boron neutron capture therapy (BNCT) and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these carborane-containing tetraphenyl porphyrin compounds to methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.
    Type: Grant
    Filed: May 20, 2004
    Date of Patent: February 7, 2006
    Assignee: Brookhaven Science Associates, LLC
    Inventors: Haitao Wu, Michiko Miura