Patents by Inventor Michiko Seyama
Michiko Seyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210177267Abstract: A component concentration measurement device includes a light application unit that applies pulsed beam light of a wavelength that is absorbed by a target substance for measurement to a site of measurement, and a detection unit that detects a photoacoustic signal generated in the site of measurement where the beam light emitted from the light application unit has been applied. The light application unit applies the pulsed beam light with a pulse width at which a photoacoustic wave that occurs at a rising edge of a light pulse and a photoacoustic wave that occurs at a falling edge of the light pulse do not interfere with each other.Type: ApplicationFiled: April 19, 2019Publication date: June 17, 2021Inventors: Yujiro Tanaka, Masahito Nakamura, Daichi Matsunaga, Michiko Seyama
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Publication number: 20210161419Abstract: A component concentration measuring apparatus includes: a dielectric spectroscopy portion that irradiates a measurement subject with electromagnetic waves, thereby acquiring a complex permittivity spectrum; a signal processing portion that standardizes an imaginary part or an imaginary part spectrum of a complex permittivity at a frequency other than a frequency of an isosbestic point of the measurement subject, using an imaginary part of a complex permittivity at the frequency of the isosbestic point, out of the complex permittivity spectrum; and a calculating portion that applies a calibration model generated in advance from an imaginary part or an imaginary part spectrum of a complex permittivity of a sample whose component concentration is known, to the imaginary part or the imaginary part spectrum of the complex permittivity standardized by the signal processing portion, thereby calculating a component concentration of the measurement subject.Type: ApplicationFiled: April 12, 2019Publication date: June 3, 2021Inventors: Masahito Nakamura, Takuro Tajima, Michiko Seyama
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Publication number: 20210121105Abstract: A light irradiation unit configured to irradiate a measurement part with a light beam that has a wavelength absorbed by glucose and a detection unit configured to detect a photoacoustic signal generated from the measurement part irradiated with the light beam emitted from the light irradiation unit are included. The light irradiation unit irradiates the measurement part by scanning the light beam 2-dimensionally. The measurement part is irradiated with the light beam through raster scanning. For example, the light beam has a beam diameter of about 100 ?m and is scanned at a scanning speed of about 100 ?m/10 ms.Type: ApplicationFiled: April 5, 2019Publication date: April 29, 2021Inventors: Katsuhiro Ajito, Michiko Seyama, Daichi Matsunaga, Masahito Nakamura, Yujiro Tanaka
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Publication number: 20210123819Abstract: A heat flux sensor including two temperature sensors is used to obtain time-series data of a core temperature of a living body, and a blood flow rate in a vicinity of the heat flux sensor is measured by a blood flow sensor. In an arithmetic circuit, a delay time until a fluctuation of the core temperature of the living body is reflected on an epidermis temperature is calculated on the basis of the blood flow rate measured by the blood flow sensor and a previously prepared relation between the blood flow rate and the delay time until the fluctuation of the core temperature of the living body is reflected on the epidermis temperature, and a time corresponding to the core temperature of the living body on the basis of the delay time is corrected.Type: ApplicationFiled: May 14, 2019Publication date: April 29, 2021Inventors: Michiko Seyama, Daichi Matsunaga, Yujiro Tanaka
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Patent number: 10881315Abstract: In a biological signal measurement system of this invention, biological digital data is generated from a biological signal measured by a biological signal measurement apparatus, and first feature amount data extracted from the biological digital data and downsized biological digital data are transmitted to a portable terminal. In a biological information measurement apparatus of this invention, biological feature amount data is extracted from measured biological waveform data, and at least one of the biological waveform data and the biological feature amount data is transmitted to an external device. It is possible to provide a biological signal measurement system capable of continuously measuring a biological signal for a long time without disturbing daily life and provide a biological information measurement apparatus capable of implementing downsizing and long life of a battery.Type: GrantFiled: August 4, 2015Date of Patent: January 5, 2021Assignee: NIPPON TELEGRAPH AND TELEPHONE CORPORATIONInventors: Kei Kuwabara, Takayuki Ogasawara, Nobuaki Matsuura, Michiko Seyama, Hiroshi Koizumi, Ryusuke Kawano, Kazuhiko Takagahara, Kazuyoshi Ono, Takako Ishihara, Yasuhiro Sato, Shingo Tsukada, Nahoko Kasai, Koji Sumitomo
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Publication number: 20200405273Abstract: A base material is made of a flexible resin, and formed in the shape of a sheet provided with a hollow portion. The base material can be wrapped around, for example, a forearm, an upper arm, a wrist, or the like. A sweat absorption unit is made of a plurality of fibers, and is arranged at the hollow portion for taking up sweat that has been taken in by a suction port. The sweat absorption unit is made of, for example, paper made of cellulose. A sodium ion detection electrode, a potassium ion detection electrode, and a reference electrode are allowed to contact the sweat that has been suctioned from the suction port of the sweat absorption unit and taken up into the sweat absorption unit, to detect ions contained in the sweat.Type: ApplicationFiled: February 20, 2019Publication date: December 31, 2020Inventors: Michiko Seyama, Yujiro Tanaka
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Publication number: 20200405272Abstract: A suction channel is made of a flexible resin, and is formed in a base. The suction channel suctions sweat that has come into contact with the detection electrode. The suction channel makes use of surface tension from micro channels to suction liquid into an interior from a suction port. A sodium ion detection electrode, a potassium ion detection electrode, and a reference electrode, which are detection electrodes for detecting ions contained in the sweat, are formed on an inner wall of a channel of the suction channel.Type: ApplicationFiled: February 20, 2019Publication date: December 31, 2020Inventors: Michiko Seyama, Yujiro Tanaka
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Patent number: 10799136Abstract: A bioelectrode includes a fitting member (1106) formed by an electrically insulating member fixed on a surface of a garment (1100) that comes in contact with a living body (1000), an electrode part (1101a) formed by a conductive member fixed on a surface of the fitting member (1106) that comes in contact with the living body (1000), a connector (1102a) fixed to the fitting member (1106) and configured to connect a bioelectric signal measurement device, a wiring line (1103a) fixed to the fitting member (1106) and configured to electrically connect the connector (1102a) and the electrode part (1101a), and an electrically-insulating insulating member (1105) configured to cover a portion within the surface of the wiring line (1103a) that comes in contact with the living body (1000).Type: GrantFiled: December 7, 2015Date of Patent: October 13, 2020Assignees: NIPPON TELEGRAPH AND TELEPHONE CORPORATION, TORAY INDUSTRIES, INC.Inventors: Kazuhiko Takagahara, Ryusuke Kawano, Takako Ishihara, Michiko Seyama, Ryoichi Kasahara, Yasuhiro Sato, Atsushi Horiuchi, Masanobu Sato, Emiko Ishikawa, Keiji Takeda, Noriko Nagai
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Patent number: 9880101Abstract: A flow rate measurement apparatus includes a light oscillator; a thin metallic film which causes surface plasmon resonance by light output from the light oscillator; a focusing unit which fixes the thin metallic film and converts the output light of the light oscillator into incident light having a plurality of incident angles to focus the incident light at a location of a focal line in a straight line shape on the thin metallic film; a measurement part having antibody fixed areas to which an antibody is fixed and reference areas to which an antibody is not fixed, the antibody fixed areas and the reference areas being alternately arranged at a location along the focal line location on the thin metallic film; a light receiver which receives reflected light, at the focal line location, of the output light by surface plasmon resonance occurring at the focal line location, at each of the plurality of incident light angles; an SPR angle calculator which obtains a temporal change of an SPR angle in each of the antiType: GrantFiled: April 5, 2013Date of Patent: January 30, 2018Assignee: Nippon Telegraph And Telephone CorporationInventors: Yuzuru Iwasaki, Tsutomu Horiuchi, Michiko Seyama, Toru Miura, Tsuneyuki Haga, Jun-ichi Takahashi, Tsuyoshi Hayashi
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Publication number: 20170340226Abstract: A bioelectrode includes a fitting member (1106) formed by an electrically insulating member fixed on a surface of a garment (1100) that comes in contact with a living body (1000), an electrode part (1101a) formed by a conductive member fixed on a surface of the fitting member (1106) that comes in contact with the living body (1000), a connector (1102a) fixed to the fitting member (1106) and configured to connect a bioelectric signal measurement device, a wiring line (1103a) fixed to the fitting member (1106) and configured to electrically connect the connector (1102a) and the electrode part (1101a), and an electrically-insulating insulating member (1105) configured to cover a portion within the surface of the wiring line (1103a) that comes in contact with the living body (1000).Type: ApplicationFiled: December 7, 2015Publication date: November 30, 2017Inventors: Kazuhiko TAKAGAHARA, Ryusuke KAWANO, Takako ISHIHARA, Michiko SEYAMA, Ryoichi KASAHARA, Yasuhiro SATO, Atsushi HORIUCHI, Masanobu SATO, Emiko ISHIKAWA, Keiji TAKEDA, Noriko NAGAI
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Publication number: 20170224244Abstract: In a biological signal measurement system of this invention, biological digital data is generated from a biological signal measured by a biological signal measurement apparatus, and first feature amount data extracted from the biological digital data and downsized biological digital data are transmitted to a portable terminal. In a biological information measurement apparatus of this invention, biological feature amount data is extracted from measured biological waveform data, and at least one of the biological waveform data and the biological feature amount data is transmitted to an external device. It is possible to provide a biological signal measurement system capable of continuously measuring a biological signal for a long time without disturbing daily life and provide a biological information measurement apparatus capable of implementing downsizing and long life of a battery.Type: ApplicationFiled: August 4, 2015Publication date: August 10, 2017Inventors: Kei KUWABARA, Takayuki OGASAWARA, Nobuaki MATSUURA, Michiko SEYAMA, Hiroshi KOIZUMI, Ryusuke KAWANO, Kazuhiko TAKAGAHARA, Kazuyoshi ONO, Takako ISHIHARA, Yasuhiro SATO, Shingo TSUKADA, Nahoko KASAI, Koji SUMITOMO
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Patent number: 8916389Abstract: An object of the present invention is to provide an element for SPR measurement without the need of a mechanical solution-sending mechanism.Type: GrantFiled: June 26, 2007Date of Patent: December 23, 2014Assignee: Nippon Telegraph and Telephone CorporationInventors: Yuzuru Iwasaki, Michiko Seyama, Toru Miura, Tsutomu Horiuchi, Tsuneyuki Haga, Serge Camou
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Publication number: 20140363337Abstract: The present invention relates to a chip for optical analysis. In particular, the present invention relates to an optical sensor handling a liquid sample, which is a chip for analysis that can be used for selectively measuring a biologically-relevant substance or a chemical substance such as an environmental pollutant or a health affecting substance in a liquid to be measured. The chip for optical analysis of the present invention is characterized in that (1) an adsorption region (filter region) is provided between a sample introduction section and the observation section in a passage of the chip for analysis, (2) a bypass passage is provided in the passage (main passage) of the chip for analysis, and a time lag is generated between samples passed through the main passage and passed through a bypass passage, and (3) a measurement region and a reference region are provided in the observation section of the chip for analysis.Type: ApplicationFiled: August 25, 2014Publication date: December 11, 2014Inventors: Michiko Seyama, Serge Camou, Yuzuru Iwasaki, Toru Miura, Jyunichi Takahashi, Tsuneyuki Haga, Tsutomu Horiuchi
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Patent number: 8859267Abstract: The present invention relates to a chip for optical analysis. In particular, the present invention relates to an optical sensor handling a liquid sample, which is a chip for analysis that can be used for selectively measuring a biologically-relevant substance or a chemical substance such as an environmental pollutant or a health affecting substance in a liquid to be measured. The chip for optical analysis of the present invention is characterized in that (1) an adsorption region (filter region) is provided between a sample introduction section and the observation section in a passage of the chip for analysis, (2) a bypass passage is provided in the passage (main passage) of the chip for analysis, and a time lag is generated between samples passed through the main passage and passed through a bypass passage, and (3) a measurement region and a reference region are provided in the observation section of the chip for analysis.Type: GrantFiled: June 11, 2007Date of Patent: October 14, 2014Assignee: Nippon Telegraph and Telephone CorporationInventors: Michiko Seyama, Serge Camou, Yuzuru Iwasaki, Toru Miura, Jyunichi Takahashi, Tsuneyuki Haga, Tsutomu Horiuchi
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Patent number: 8663560Abstract: A flow cell includes: a flow channel through which a sample solution flows; an inlet section which communicates with the flow channel and to which the sample solution is supplied; a transfer section which includes a plurality of opening sections, one end side of which communicates with the flow channel and an other side of which opens to outside air, and which communicates with the flow channel, and draws in and guides the sample solution supplied into the inlet section to the flow channel; a detecting section which faces the sample solution in the flow channel; and a sealing member which unsealably seals at least either one of the opening section or the inlet section.Type: GrantFiled: May 26, 2009Date of Patent: March 4, 2014Assignee: Nippon Telegraph and Telephone CorporationInventors: Tsutomu Horiuchi, Toru Miura, Yuzuru Iwasaki, Michiko Seyama, Tsuyoshi Hayashi, Jun-ichi Takahashi, Tsuneyuki Haga
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Patent number: 8647589Abstract: An object of the invention is to provide various flow cells and a method for manufacturing the same, in which formation of a groove on a substrate and formation of components such as an electrode, auxiliary parts such as a pump are not necessary. The inventive flow cells are capable of realize complicated chemical analysis or synthesis or the like. A channel of a porous member provided on a sample-incompatible substrate is formed; the porous member is composed of an air non-contact region having a network structure and an air contact region covering the air non-contact region and having a lower pore density than the air non-contact region; in which a capillary force to be generated within the porous member is a drive force for pumping a liquid.Type: GrantFiled: July 20, 2012Date of Patent: February 11, 2014Assignee: Nippon Telegraph and Telephone CorporationInventors: Tsutomu Horiuchi, Toru Miura, Yuzuru Iwasaki, Jyunichi Takahashi, Katsuyoshi Hayashi, Tsuneyuki Haga, Michiko Seyama, Serge Camou
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Patent number: 8531658Abstract: A measuring chip installation/removal device of the present invention secures and removes a measuring chip to and from the top surface of an SPR measurement device that measures a specimen in the measuring chip by surface plasmon resonance. The measuring chip installation/removal device includes: a chip carrier on which the measuring chip is mounted; a chip carrier guide that guides the chip carrier on the top surface; and a first magnet provided in the chip carrier, and a second magnet is provided in the chip carrier guide. Orientation of a magnetic force received by the first magnet from the second magnet is reversed by displacing the chip carrier guide, so that the chip carrier is secured to or removed from the top surface.Type: GrantFiled: October 28, 2009Date of Patent: September 10, 2013Assignee: Nippon Telegraph and Telephone CorporationInventors: Tsutomu Horiuchi, Toru Miura, Yuzuru Iwasaki, Michiko Seyama, Tsuyoshi Hayashi, Jun-ichi Takahashi, Tsuneyuki Haga
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Patent number: 8398936Abstract: In a capillary pump unit, a capillary pump including a plurality of through portions making a first point and a second point of an approximately flat-plate-shaped base communicable with each other are formed in the base, and a sample liquid is transferred from the first point to the second point by capillary force by the through portions.Type: GrantFiled: January 7, 2009Date of Patent: March 19, 2013Assignee: Nippon Telegraph and Telephone CorporationInventors: Tsutomu Horiuchi, Toru Miura, Yuzuru Iwasaki, Michiko Seyama, Tsuyoshi Hayashi, Jun-ichi Takahashi, Tsuneyuki Haga
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Patent number: 8355135Abstract: A surface plasmon resonance measuring device includes a light source (2) which irradiates, with condensed light, a sample cell (10) having the characteristic structure of the reflectance of light that is formed in advance as a code from at least either of a substance film to be measured and a substance film different from the substance film to be measured, from a surface opposite to one on which the substance film to be measured is immobilized to a metal thin film, a CCD camera (5) which detects light reflected by the sample cell (10), and a data processing device (6) which extracts the identification code of the sample cell (10) from the feature of an image sensed by the camera (5).Type: GrantFiled: January 16, 2009Date of Patent: January 15, 2013Assignee: Nippon Telegraph and Telephone CorporationInventors: Yuzuru Iwasaki, Tsutomu Horiuchi, Michiko Seyama, Toru Miura, Tsuneyuki Haga, Tsuyoshi Hayashi
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Publication number: 20120288421Abstract: An object of the invention is to provide various flow cells and a method for manufacturing the same, in which formation of a groove on a substrate and formation of components such as an electrode, auxiliary parts such as a pump are not necessary. The inventive flow cells are capable of realize complicated chemical analysis or synthesis or the like. A channel of a porous member provided on a sample-incompatible substrate is formed; the porous member is composed of an air non-contact region having a network structure and an air contact region covering the air non-contact region and having a lower pore density than the air non-contact region; in which a capillary force to be generated within the porous member is a drive force for pumping a liquid.Type: ApplicationFiled: July 20, 2012Publication date: November 15, 2012Applicant: NIPPON TELEGRAPH AND TELEPHONE CORPORATIONInventors: Tsutomu Horiuchi, Toru Miura, Yuzuru Iwasaki, Jyunichi Takahashi, Katsuyoshi Hayashi, Tsuneyuki Haga, Michiko Seyama, Serge Camou