Patents by Inventor Michiko Yamayoshi

Michiko Yamayoshi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of microbial infection with interleukin 1 polypeptides
    Patent number: 5494663
    Abstract: DNAs encoding polypeptides having interleukin 1, vectors inserted with said DNAs, hosts transformed with said recombinant vectors, polypeptides having interleukin 1 activity which are produced by cultivation of the transformed hosts, derivatives of the polypeptides, pharmaceutical composition containing said polypeptides or derivatives, their use as an antitumor or antiinfectious agent, and processes for the preparation thereof.
    Type: Grant
    Filed: June 2, 1994
    Date of Patent: February 27, 1996
    Assignee: Dainippon Pharmaceutical Co., Ltd.
    Inventors: Masaaki Yamada, Yasuji Furutani, Michiko Yamayoshi, Mitsue Notake, Junichi Yamagishi
  • Treatment of sarcoma with interleukin 1.alpha. polypeptides
    Patent number: 5376639
    Abstract: DNAs encoding polypeptides having interleukin 1, vectors inserted with said DNAs, hosts transformed with said recombinant vectors, polypeptides having interleukin 1 activity which are produced by cultivation of the transformed hosts, derivatives of the polypeptides, pharmaceutical composition containing said polypeptides or derivatives, their use as an antitumor or antiinfectious agent, and processes for the preparation thereof.
    Type: Grant
    Filed: September 30, 1992
    Date of Patent: December 27, 1994
    Assignee: Dainippon Pharmaceutical Co., Ltd.
    Inventors: Masaaki Yamada, Yasuji Furutani, Michiko Yamayoshi, Mitsue Notake, Junichi Yamagishi
  • Modified polypeptides of IL-1.alpha.
    Patent number: 5290917
    Abstract: Novel polypeptides having a modified amino acid sequence of human interleukin 1.alpha. polypeptides in which a certain amino acid residue(s) in said amino acid sequence is(are) exchanged for other amino acid residue(s). Said polypeptides having no capacity of induction of production of prostaglandin E.sub.2 while maintaining other biological activities of human interleukin 1 such as activation of lymphocyte and being expected to be useful as a medicament.
    Type: Grant
    Filed: April 5, 1991
    Date of Patent: March 1, 1994
    Assignee: Dainippon Pharmaceutical Co., Ltd.
    Inventors: Michiko Yamayoshi, Hitoshi Kawashima, Junichi Yamagishi, Hirotada Kotani, Ryuji Furuta, Toshikazu Fukui