Patents by Inventor Michinori Waki

Michinori Waki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polypeptide transition metal salts and method of enhancing anti-HIV activity of polypeptide
    Patent number: 6329498
    Abstract: The present invention provides a novel salt compound of a polypeptide represented by formula I and a transition metal which has high antiviral activity against human immunodeficiency virus (HIV).
    Type: Grant
    Filed: April 14, 1999
    Date of Patent: December 11, 2001
    Assignee: Seikagaku Corporation
    Inventors: Akiyoshi Matsumoto, Michinori Waki
  • Cinnamic acid derivative
    Patent number: 6107410
    Abstract: The invention provides a cinnamic acid derivative having a novel spacer introduced into cinnamic acid which is photodimerizable, a cinnamic acid-polysaccharide derivative photocurable with high sensitivity and efficiency obtainable by introducing the above cinnamic acid derivative into a host polysaccharide such as a glycosaminoglycan, and a photocrosslinked cinnamic acid-polysaccharide derivative obtainable by exposing the same cinnamic acid-polysaccharide derivative to ultraviolet light irradiation.
    Type: Grant
    Filed: December 22, 1998
    Date of Patent: August 22, 2000
    Assignee: Seikagaku Corporation
    Inventors: Michinori Waki, Kenji Miyamoto, Yoshihiro Motani
  • Photocured cross-linked-hyaluronic acid gel and method of preparation thereof
    Patent number: 6031017
    Abstract: A photocured crosslinked-hyaluronic acid gel, which has a storage modulus (G') of from 50 to 1500 Pa, a loss modulus (G") of from 10 to 300 Pa, and a tangent delta (G"/G') of from 0.1 to 0.8 in dynamic viscoelasticity at a frequency of 10 Hz, and which is a hydrogel obtained by irradiation with ultraviolet rays of a photoreactive hyaluronic acid derivative in which a photoreactive crosslinking group is chemically linked to a functional group of the hyaluronic acid and crosslinking of mutual photoreactive crosslinking groups, methods for preparing the same, and uses thereof as biomedical materials.
    Type: Grant
    Filed: May 5, 1998
    Date of Patent: February 29, 2000
    Assignee: Seikagaku Corporation
    Inventors: Michinori Waki, Kenji Miyamoto
  • Cinnamic acid derivative
    Patent number: 6025444
    Abstract: The invention provides a cinnamic acid derivative having a novel spacer introduced into cinnamic acid which is photodimerizable, a cinnamic acid-polysaccharide derivative photocurable with high sensitivity and efficiency obtainable by introducing the above cinnamic acid derivative into a host polysaccharide such as a glycosaminoglycan, and a photocrosslinked cinnamic acid-polysaccharide derivative obtainable by exposing the same cinnamic acid-polysaccharide derivative to ultraviolet light irradiation.
    Type: Grant
    Filed: May 27, 1997
    Date of Patent: February 15, 2000
    Assignees: Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation), Fuji Photo Film Co., Ltd.
    Inventors: Michinori Waki, Kenji Miyamoto, Yoshihiro Motani
  • Polypeptide and anti-HIV agent prepared therefrom
    Patent number: 5776899
    Abstract: A polypeptide represented by formula (I), and one example of such polypeptide be represented as formula 1 is presented. The above presented polypeptide may be useful in a pharmaceutical composition as an antimicrobial or antiviral agent, specifically as an anti-HIV agent and as a component of the DNA-transfecting systems for gene therapy.
    Type: Grant
    Filed: June 13, 1995
    Date of Patent: July 7, 1998
    Assignee: Seikagaku Corporation
    Inventors: Akiyoshi Matsumoto, Michinori Waki
  • Pharmaceutical compositions of lipopolysaccharide-binding polypeptides
    Patent number: 5710128
    Abstract: A novel polypeptide sequence having the formula ##STR1## in which A.sub.1 is a hydrogen or at least one and no more than two amino acids selected from the group consisting of lysine and arginine,A.sub.2 is a tyrosine, phenylalanine or tryptophan residue,A.sub.3 is an arginine or lysine residue,A.sub.4 is at least one and no more than two amino acids selected from the group consisting of lysine and arginine, andA.sub.5 is an --OH or an NH.sub.2, is described.The polypeptide may be used in a pharmaceutical composition as an antimicrobial or antiviral agent, specifically as an anti-HIV agent.
    Type: Grant
    Filed: April 21, 1995
    Date of Patent: January 20, 1998
    Inventors: Nobutaka Fujii, Naoki Yamamoto, Akiyoshi Matsumoto, Michinori Waki
  • Polypeptides with affinity to lipopolysaccharides and their uses
    Patent number: 5449752
    Abstract: A novel polypeptide sequence having the formula ##STR1## in which A.sub.1 is a hydrogen or at least one and no more than two amino acids selected from the group consisting of lysine and arginine,A.sub.2 is a tyrosine, phenylalanine or tryptophan residue,A.sub.3 is an arginine or lysine residue,A.sub.4 is at least one and no more than two amino acids selected from the group consisting of lysine and arginine, andA.sub.5 is an --OH or an NH.sub.2, is described.The polypeptide may be used in a pharmaceutical composition as an antimicrobial or antiviral agent, specifically as an anti-HIV agent.
    Type: Grant
    Filed: April 29, 1992
    Date of Patent: September 12, 1995
    Assignee: Seikagaku Kogyo K.K.
    Inventors: Nobutaka Fujii, Naoki Yamamoto, Akiyoshi Matsumoto, Michinori Waki