Abstract: A two-component curable coating agent capable of forming a surface protective layer having excellent weather resistance, acid resistance, fouling resistance, and elongation properties, and a multilayer film including a surface protective layer that is a cured film of the two-component curable coating agent. The two-component curable coating agent includes a main agent that contains a polyol containing an epoxy polyol (P) and an acrylic polyol (A), and a curing agent that contains a polyisocyanate, the epoxy polyol (P) being a reaction product of an epoxy group-containing compound (e) and a carboxyl group-containing compound (c). Furthermore, the multilayer film includes a substrate layer; a surface protective layer that is layered on and integrated with a first surface of the substrate layer and that is a cured film of the two-component curable coating agent; and an adhesive layer that is layered on and integrated with a second surface of the substrate layer.

Abstract: A novel disinfectant is disclosed. Said disinfectant is a compound 1,n-bis(N.sup.5 -m-, or p-trifluoromethyl-phenyl-N.sup.1 -biguanido)-C.sub.3 -C.sub.10 -alkane. The m-trifluoro-C.sub.6 derivative is a known compound. The compounds of the present invention exhibit germicidal effect against Pseudomonas aeruginosa, Proteus vulgaris and Alcaligenes faecalis at concentrations of 1/4-1/8 of the effective concentration for chlorhexidine. Against other microorganisms, the compounds are effective at the same level as chlorhexidine.

Abstract: A novel bis-biguanide compound suitable for use as a disinfectant has the following formula: ##STR1## where n is an integer from 2 to 10 inclusive. A pharmaceutically acceptable salt, particularly gluconate salt of the compound is also useful as a disinfectant. The bis-biguanide compound has germicidal activities comparable to those of widely used chlorhexidine with respect to width of antibacterial spectrum and is superior to chlorhexidine in immediate effectiveness. It exhibits excellent germicidal activities against Pyocyaneus bacilli, on which chlorhexidine has poor effect.