Patents by Inventor Michio Kimrua

Michio Kimrua has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of detecting autoantibody present in the serum of rheumatic
    Patent number: 6225442
    Abstract: A reagent for immunologically detecting rheumatism containing as an antigen at least one mammalian protein selected from among ezrin, radixin and moesin and/or a peptide composed of at least nine consecutive amino acid residues found in the amino acid sequences of ezrin, radixin and moesin; and a method of detecting autoantibodies present in the serum of a rheumatic. An immunological reaction using this reagent enables precritical or early diagnosis of rheumatism. An immunological detection using the above autoantigenic proteins is convenient and reliable as an early serodiagnostic method based on rheumatism-specific antigens.
    Type: Grant
    Filed: January 22, 1999
    Date of Patent: May 1, 2001
    Assignees: Dade Behring Marburg GmbH, Hoechst Marion Roussel Ltd.
    Inventors: Masako Wagatsuma, Michio Kimrua, Hiroshi Watanabe, Fujio Takeuchi
  • Method of detecting autoantibody present in the serum of rheumatic
    Patent number: 5976810
    Abstract: A reagent for immunologically detecting rheumatism containing as an antigen at least one mammalian protein selected from among ezrin, radixin and moesin and/or a peptide composed of at least nine consecutive amino acid residues found in the amino acid sequences of ezrin, radixin and moesin; and a method of detecting autoantibodies present in the serum of a rheumatic. An immunological reaction using this reagent enables precritical or early diagnosis of rheumatism. An immunological detection using the above autoantigenic proteins is convenient and reliable as an early serodiagnostic method based on rheumatism-specific antigens.
    Type: Grant
    Filed: May 8, 1997
    Date of Patent: November 2, 1999
    Assignee: Hoechst Pharmaceuticals & Chemicals K.K.
    Inventors: Masako Wagatsuma, Michio Kimrua, Hiroshi Watanabe, Fujio Takeuchi