Patents by Inventor Michio Kubota

Michio Kubota has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060172059
    Abstract: The present invention has objects for providing a method for inhibiting the moisture variation in compositions, a composition whose moisture variation is inhibited, and an agent for inhibiting the moisture variation in compositions. The objects are solved by providing a method for inhibiting the moisture variation in compositions comprising incorporating into a composition a saccharide-derivative(s) of ?,?-trehalose as an effective ingredient, a composition whose moisture variation is inhibited by incorporating the saccharide-derivative(s), a moisture variation inhibiting agent containing the saccharide-derivative(s) as an effective ingredient, and uses thereof.
    Type: Application
    Filed: December 15, 2003
    Publication date: August 3, 2006
    Inventors: Kanou Takeuchi, Michio Kubota, Toshio Miyake
  • Publication number: 20060134197
    Abstract: The present invention has objects to provide a method of lowering the unpleasant taste and/or smell of compositions, and an agent for lowering unpleasant taste and/or smell. The objects are solved by providing a method of lowering unpleasant taste and/or smell, comprising a step of incorporating an saccharide derivative of ?,?-trehalose in compositions; a composition with lowered unpleasant taste and/or smell, obtainable by the method; and an agent for lowering unpleasant taste and/or smell, comprising an saccharide derivatives of ?,?-trehalose as an effective ingredients.
    Type: Application
    Filed: December 24, 2003
    Publication date: June 22, 2006
    Inventors: Yukio Uchida, Kanou Takeuchi, Michio Kubota, Toshio Miyake
  • Publication number: 20060008791
    Abstract: The present invention has the object to dehydrate hydrous matters without denaturing or deteriorating them by using a dehydrating agent comprising an anhydrous cyclotetrasaccharide, and provides a dehydrating agent comprising the cyclotetrasaccharide; a method for dehydrating hydrous matters through a step of incorporating, contacting or coexisting the cyclotetrasaccharide into, with, or in the hydrous matters; and dehydrated products obtainable thereby.
    Type: Application
    Filed: January 17, 2002
    Publication date: January 12, 2006
    Inventors: Michio Kubota, Tomoyuki Nishimoto, Hajime Aga, Shigeharu Fukuda, Toshio Miyake
  • Publication number: 20050267067
    Abstract: The present invention has an object to provide a radical reaction inhibitory agent for inhibiting unsaturated compounds from decomposing through radical reactions, a method for inhibiting the formation of free radicals from unsaturated compounds and radical reactions thereof, and a composition which is suppressed in radical formation, radical reaction, or progress thereof. The object is solved by establishing a radical reaction inhibitory agent containing as an effective ingredient cyclotetrasaccharide or a mixture of cyclotetrasaccharide and its saccharide derivative(s), a method for inhibiting the formation of free radicals from unsaturated compounds and radical reactions thereof, and a composition which contains the agent and which is suppressed in radical formation, radical reaction, or progress thereof.
    Type: Application
    Filed: August 26, 2003
    Publication date: December 1, 2005
    Inventors: Kazuyuki Oku, Michio Kubota, Shigeharu Fukuda, Toshio Miyake
  • Publication number: 20050123671
    Abstract: A reduction inhibitory agent for active oxygen eliminating activity which comprises cyclotetrasaccharide i.e., cyclo{6}-?-D-glucopyranosyl-(1 3)-?-D-glucopyranosyl-(1 6)-?-D-glucopyranosyl-(1 3)-?-D-glucopyranosyl-(1), as an effective ingredient, a method for inhibiting the reduction of active oxygen eliminating activity which comprises incorporating either cyclotetrasaccharide or the reduction inhibitory agent into plant edible products and/or plant antioxidants, and a composition where the reduction of active oxygen eliminating activity of the plant edible products and/or plant antioxidants has been satisfactorily inhibited by the method.
    Type: Application
    Filed: October 18, 2004
    Publication date: June 9, 2005
    Applicant: KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKUJO
    Inventors: Kazuyuki Oku, Michio Kubota, Shigeharu Fukuda, Toshio Miyake
  • Publication number: 20050065030
    Abstract: Disclosed are a reduction inhibitory agent for active oxygen eliminating activity, comprising: (a) at least 10% (w/w) of a cyclotetrasaccharide having a basic cyclic structure in Chemical Formula 1, on a dry solid basis; and Chemical Formula 1: (b) at least one member selected from the group consisting of saccharides and edible fibers; a method for inhibiting the reduction of active oxygen eliminating activity, comprising a step of incorporating at least one percent (w/w) of a cyclotetrasaccharide having a basic cyclic structure in Chemical Formula 1 to a plant substance, on a dry solid basis, into said plant substance with active oxygen eliminating activity in an aqueous system; and a composition obtainable by incorporating at least one percent (w/w) of a cyclotetrasaccharide having a basic cyclic structure in Chemical Formula 1 to said plant substance, on a dry solid basis, into a plant substance with active oxygen eliminating activity to inhibit the reduction of the activity of said plant substance.
    Type: Application
    Filed: November 12, 2004
    Publication date: March 24, 2005
    Applicant: KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO
    Inventors: Kazuyuki Oku, Michio Kubota, Shigeharu Fukuda, Toshio Miyake
  • Publication number: 20050013914
    Abstract: The first object of the present invention is to provide a method for preparing an aroma-retaining material, which enables to increase the adsorbed aroma amount, retain the aroma for a long period of time, and impart stability. The second object of the present invention is to provide an aroma-retaining material, which can retain aroma for a long period of time and has satisfactory stability. The third object of the present invention is to provide a composition comprising the aroma-retaining material. The forth object of the present invention is to provide an aroma-retaining agent, which enables to stabilize an aromatic substance. The fifth object of the present invention is to provide a retained-releasing bactericide comprising the aroma-retaining material.
    Type: Application
    Filed: November 21, 2002
    Publication date: January 20, 2005
    Inventors: Kazuyuki Oku, Michio Kubota, Shigeharu Fukuda, Toshio Miyake
  • Publication number: 20050009017
    Abstract: The object of the present invention is to provide an ?-isomaltosyl-transferring enzyme which forms a cyclotetrasaccharide having the structure of cyclo{?6)-?-D-glucopyranosyl-(1?3)-?-D-glucopyranosyl-(1?6)-?-D-glucopyranosyl-(1?3)-?-D-glucopyranosyl-(1?} from a saccharide having a glucose polymerization degree of at least three and having both the ?-1,6 glucosidic linkage as a linkage at the non-reducing end and the ?-1,4 glucosidic linkage other than the linkage at the non-reducing end; microorganisms which produce the enzyme; process for producing the enzyme; cyclotetra-saccharide or saccharide compositions comprising the same; and uses thereof.
    Type: Application
    Filed: May 22, 2001
    Publication date: January 13, 2005
    Inventors: Michio Kubota, Tomoyuki Nishimoto, Hajime Aga, Shigeharu Fukuda, Toshio Miyake
  • Publication number: 20040253690
    Abstract: The object of the present invention is to provide a novel process for producing isomaltose and uses thereof and is solved by providing a process for producing isomaltose characterized in that it comprises the steps of allowing &agr;-isomaltosylglucosaccharide-forming enzyme, in the presence or the absence of &agr;-isomaltosyl-transferring enzyme, to act on saccharides, which have a glucose polymerization degree of at least two and &agr;-1,4 glucosidic linkage as a linkage at the non-reducing end, to form &agr;-isomaltosylglucosaccharides, which have a glucose polymerization degree of at least three, &agr;-1,6 glucosidic linkage as a linkage at the non-reducing end, and &agr;-1,4 glucosidic linkage as a linkage other than the non-reducing end, and/or to form cyclo{→6)-&agr;-D-glucopyranosyl-(1→3)-&agr;-D-glucopyranosyl-(1→6)-&agr;-D-glucopyranosyl-(1→3)-&agr;-D-glucopyranosyl-(1→}; allowing isomaltose-releasing enzyme to act on the formed saccharides to release isomaltose; an
    Type: Application
    Filed: March 5, 2003
    Publication date: December 16, 2004
    Inventors: Michio Kubota, Tomoyuki Nishimoto, Takanobu Higashiyama, Hikaru Watanabe, Shigeharu Fukuda, Toshio Miyake
  • Publication number: 20040236097
    Abstract: The object of the present invention is to provide a novel glycosyl derivative of cyclotetrasaccharide represented by cyclo{→6)-&agr;-D-glucopyranosyl-(1→3)-&agr;-D-glucopyranosyl-(1→6)-&agr;-D-glucopyranosyl-(1→3)-&agr;-D-glucopyranosyl-(1→}, and it is solved by providing a branched cyclotetrasaccharide, wherein one or more hydrogen atoms in the hydroxyl groups of cyclotetrasaccharide are replaced with an optionally substituted glycosyl group, with the proviso that, when only one hydrogen atom in the C-6 hydroxyl group among the above hydrogen atoms is substituted with an optionally-substituted glycosyl group, the substituted glycosyl group is one selected from those excluding D-glucosyl group.
    Type: Application
    Filed: September 9, 2003
    Publication date: November 25, 2004
    Inventors: Hajime Aga, Takanobu Higashiyama, Hiraku Watanabe, Tomohiko Sonoda, Michio Kubota
  • Patent number: 6808651
    Abstract: A thermoplastic shaped-body of trehalose obtainable by concentrating a trehalose solution by heating either to lower the moister content of the solution to a level of not higher than about 8.3 w/w % in the presence of a substance capable of lowering the adhesion of a trehalose solution, or to lower the moisture content of the trehalose solution to a level of not higher than about 2.4 w/w %.
    Type: Grant
    Filed: October 24, 2000
    Date of Patent: October 26, 2004
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Naohiko Katagiri, Yasuo Takeuchi, Michio Kubota, Toshio Miyake
  • Publication number: 20040209841
    Abstract: The object of the present invention is to provide a composition of metal ion compound whose inherent and unsatisfactory properties for its industrial application such as deliquescence, reducing power, oxidizing power, low solubility in water, etc., are improved; and their preparation and uses. The present invention solves the above object by providing an associate of trehalose or maltitol and a metal ion compound or bittern component, and their preparation and uses.
    Type: Application
    Filed: February 10, 2004
    Publication date: October 21, 2004
    Inventors: Kazuyuki Oku, Michio Kubota, Shigeharu Fukuda, Toshio Miyake
  • Publication number: 20040161835
    Abstract: The object of the present invention is to provide a polypeptide which can be used to produce a saccharide having the structure of cyclo{→6)-&agr;-D-glucopyranosyl-(1→3)-&agr;-D-glucopyranosyl-(1→6)-&agr;-D-glucopyranosyl-(1→3)-&agr;-D-glucopyranosyl-(1→}, a DNA encoding the polypeptide, and uses thereof.
    Type: Application
    Filed: July 11, 2003
    Publication date: August 19, 2004
    Inventors: Michio Kubota, Kazuhiko Maruta, Takuo Yamamoto, Shigeharu Fukuda
  • Patent number: 6762046
    Abstract: A polypeptide having &bgr;-fructofuranosidase activity is obtained by the expression of a microbial gene, which polypeptide contains the amino acid sequences of SEQ ID NO:1 and SEQ ID NO:2 in whole or in part as an amino acid sequence. This polypeptide is useful for producing fructofuranosyl transferred saccharides.
    Type: Grant
    Filed: November 9, 2001
    Date of Patent: July 13, 2004
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Keiji Tsusaki, Michio Kubota, Hiroto Chaen
  • Publication number: 20040121431
    Abstract: The object of the present invention is to provide a polypeptide which can be used to produce a saccharide having a structure of cyclo{→6)-&agr;-D-glucopyranosyl-(1→3)-&agr;-D-glucopyranosyl-(1→6)-&agr;-D-glucopyranosyl-(1→3)-&agr;-D-glucopyranosyl-(1→}, a DNA encoding the polypeptide, and uses thereof.
    Type: Application
    Filed: July 15, 2002
    Publication date: June 24, 2004
    Inventors: Michio Kubota, Kazuhiko Maruta, Takuo Yamamoto, Shigeru Fukuda
  • Publication number: 20040006177
    Abstract: The present invention is to provide means of inhibiting chemical changes in unsaturated compounds by radical reactions through inhibition of radical formation in such an unsaturated compound: The present invention attains such an objective by providing an agent which comprises trehalose as an effective ingredient to form an association product between trehalose and an unsaturated compound.
    Type: Application
    Filed: March 19, 2003
    Publication date: January 8, 2004
    Inventors: Kazuyuki Oku, Michio Kubota, Shigeharu Fukuda, Toshio Miyake
  • Publication number: 20030228404
    Abstract: A crystalline &agr;-D-glucosyl &agr;-D-galactoside which has a melting point of 119-123° C.; a saccharide composition comprising the same; a process for producing the same or the saccharide composition comprising the same, which comprises (i) crystallizing &agr;-D-glucosyl &agr;-D-galactoside from its solution and (ii) collecting the grown crystalline &agr;-D-glucosyl &agr;-D-galactoside; a method for converting amorphous &agr;-D-glucosyl &agr;-D-galactoside to crystalline &agr;-D-glucosyl &agr;-D-galactoside in the presence of moisture; and a composition comprising the crystalline &agr;-D-glucosyl &agr;-D-galactoside or the saccharide composition comprising the same.
    Type: Application
    Filed: June 6, 2003
    Publication date: December 11, 2003
    Applicant: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Tomoyuki Nishimoto, Michio Kubota, Shigeharu Fukuda
  • Publication number: 20030194762
    Abstract: The object of the present invention is to provide an &agr;-isomaltosylglucosaccharide-forming enzyme, process of the same, cyclotetrasaccharide, and saccharide composition comprising the saccharide which are obtainable by using the enzyme; and is solved by establishing an &agr;-isomaltosylglucosaccharide-forming enzyme which forms a saccharide, having a glucose polymerization degree of at least three and having both the &agr;-1,6 glucosidic linkage as a linkage at the non-reducing end and the &agr;-1,4 glucosidic linkage other than the linkage at the non-reducing end, by catalyzing the &agr;-glucosyl-transfer from a saccharide having a glucose polymerization degree of at least two and having the &agr;-1,4 glucosidic linkage as a linkage at the non-reducing end without substantially increasing the reducing power; &agr;-isomaltosyl-transferring method using the enzyme; method for forming &agr;-isomaltosylglucosaccharide; process for producing a cyclotetrasaccharide having the structure of cyclo{→6)-&a
    Type: Application
    Filed: April 1, 2002
    Publication date: October 16, 2003
    Inventors: Michio Kubota, Keiji ` Tsusaki, Takanobu Higashiyama, Shigeharu Fukuda, Toshio Miyake
  • Publication number: 20030108593
    Abstract: A reduction inhibitory agent for active oxygen eliminating activity which comprises cyclotetrasaccharide, i.e., cyclo{→6}-&agr;-D-glucopyranosyl-(1→3)-&agr;-D-glucopyranosyl-(1→6)-&agr;-D-glucopyranosyl-(1→3)-&agr;-D-glucopyranosyl-(1→), as an effective ingredient, a method for inhibiting the reduction of active oxygen eliminating activity which comprises incorporating either cyclotetrasaccharide or the reduction inhibitory agent into plant edible products and/or plant antioxidants, and a composition where the reduction of active oxygen eliminating activity of the plant edible products and/or plant antioxidants has been satisfactorily inhibited by the method.
    Type: Application
    Filed: November 20, 2002
    Publication date: June 12, 2003
    Applicant: KABUSHIKI KAISHA HAY ASHIBARA SEIBUTSU KAGAKU KENKYUJO
    Inventors: Kazuyuki Oku, Michio Kubota, Shigeharu Fukuda, Toshio Miyake
  • Patent number: 6497862
    Abstract: Disclosed are a composition for inhibiting body odor which comprises trehalose and/or maltitol as an effective ingredient, a method for inhibiting body odor by using the composition, and an article incorporated with the composition.
    Type: Grant
    Filed: March 1, 2001
    Date of Patent: December 24, 2002
    Assignees: Kabushiki Kaisha Hayashibara, Seibutsu Kagaku Kenkyujo
    Inventors: Kazuyuki Oku, Michio Kubota, Shigeharu Fukuda, Toshio Miyake