Patents by Inventor Michio Nakai

Michio Nakai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant adenovirus vector having a reduced side effect
    Patent number: 8591879
    Abstract: The present invention provides a novel adenovirus vector for which inflammation during the in vivo administration thereof is alleviated by inhibiting the induction of expression of an adenovirus gene by a foreign promoter inserted into the adenovirus genome, and a method for producing the vector, a cell line for use in the production of the recombinant adenovirus vector, or a gene therapy method using the recombinant adenovirus vector.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: November 26, 2013
    Assignee: Dainippon Sumitomo Pharma Co., Ltd
    Inventors: Michio Nakai, Kazuo Komiya, Masashi Murata, Naoki Tohdoh, Izumu Saito
  • NOVEL RECOMBINANT ADENOVIRUS VECTOR HAVING A REDUCED SIDE EFFECT
    Publication number: 20120020924
    Abstract: The present invention provides a novel adenovirus vector for which inflammation during the in vivo administration thereof is alleviated by inhibiting the induction of expression of an adenovirus gene by a foreign promoter inserted into the adenovirus genome, and a method for producing the vector, a cell line for use in the production of the recombinant adenovirus vector, or a gene therapy method using the recombinant adenovirus vector.
    Type: Application
    Filed: June 3, 2011
    Publication date: January 26, 2012
    Applicant: DAINIPPON SUMITOMO PHARMA CO., LTD.
    Inventors: Michio Nakai, Kazuo Komiya, Masashi Murata, Naoki Tohdoh, Izumu Saito
  • NOVEL RECOMBINANT ADENOVIRUS VECTOR HAVING A REDUCED SIDE EFFECT
    Publication number: 20090104691
    Abstract: The present invention provides a novel adenovirus vector for which inflammation during the in vivo administration thereof is alleviated by inhibiting the induction of expression of an adenovirus gene by a foreign promoter inserted into the adenovirus genome, and a method for producing the vector, a cell line for use in the production of the recombinant adenovirus vector, or a gene therapy method using the recombinant adenovirus vector.
    Type: Application
    Filed: September 16, 2008
    Publication date: April 23, 2009
    Applicant: Dainippon Sumitomo Pharma Co., Ltd.
    Inventors: Michio Nakai, Kazuo Komiya, Masashi Murata, Naoki Tohdoh, Izumu Saito
  • Recombinant adenovirus vector having a reduced side effect
    Patent number: 7445929
    Abstract: The present invention provides a novel adenovirus vector for which inflammation during the in vivo administration thereof is alleviated by inhibiting the induction of expression of an adenovirus gene by a foreign promoter inserted into the adenovirus genome, and a method for producing the vector, a cell line for use in the production of the recombinant adenovirus vector, or a gene therapy method using the recombinant adenovirus vector.
    Type: Grant
    Filed: May 24, 2001
    Date of Patent: November 4, 2008
    Assignee: Dainippon Sumitomo Pharma Co., Ltd.
    Inventors: Michio Nakai, Kazuo Komiya, Masashi Murata, Naoki Tohdoh, Izumu Saito
  • Novel recombinant adenovirus vector with relieved side effects
    Publication number: 20040091456
    Abstract: The present invention provides a novel adenovirus vector for which inflammation during the in vivo administration thereof is alleviated by inhibiting the induction of expression of an adenovirus gene by a foreign promoter inserted into the adenovirus genome, and a method for producing the vector, a cell line for use in the production of said recombinant adenovirus vector, or a gene therapy method using said recombinant adenovirus vector.
    Type: Application
    Filed: November 26, 2002
    Publication date: May 13, 2004
    Inventors: Michio Nakai, Kazuo Komiya, Masashi Murata, Naoki Tohdoh, Izumu Saito
  • Recombinant adenovirus with removed EZA gene and method of preparation
    Patent number: 5700470
    Abstract: A recombinant DNA virus for transfecting an animal cell and bearing a foreign gene and a promoter capable of regulating expression of the foreign gene is completely deleted of the function of E2A gene. The recombinant DNA virus can thus stably transduce the foreign gene into various animal cells, which leads to continuous expression of the foreign gene in the animal cells. The continuous expression of the foreign gene can provide an effective treatment of hereditary disease.
    Type: Grant
    Filed: March 12, 1996
    Date of Patent: December 23, 1997
    Assignee: Sumitomo Pharmaceuticals Company, Limited
    Inventors: Izumu Saito, Yumi Kanegae, Michio Nakai
  • Tennis practice net
    Patent number: D269692
    Type: Grant
    Filed: December 15, 1980
    Date of Patent: July 12, 1983
    Assignee: Sony Corporation
    Inventors: Tsugio Hirabayashi, Michio Nakai
  • Tennis ball projector for training purposes
    Patent number: D269894
    Type: Grant
    Filed: December 15, 1980
    Date of Patent: July 26, 1983
    Assignee: Sony Corporation
    Inventors: Tsugio Hirabayashi, Michio Nakai