Patents by Inventor Michio Namikoshi

Michio Namikoshi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 9-deazaadenosine and its 5'-.alpha.-D-glycopyranoside isolated from the cyanobacterium Anabaena affinis strain VS-1
    Patent number: 5683895
    Abstract: The present invention is based upon the discovery that a MeOH extract of Anabaena affinis strain VS-1 showed strong cytotoxicity to L1210 murine leukemia cells, and from that extract was isolated the compounds having the following structures, Compounds 1 and 2. These two compounds are believed to be responsible for the cytotoxicity of the marine organism. This is the first report of the isolation and characterization of pyrrolo?3,2-d!pyrimidine derivatives as biosynthetic products.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 4, 1997
    Inventors: Kenneth L. Rinehart, Wayne W. Carmichael, Michio Namikoshi
  • 9-deazaadenosine and its 5'-.alpha.-D-glycopyranoside isolated from the cyanobacterium anabaena affinis strain VS-1
    Patent number: 5569757
    Abstract: The present invention is based upon the discovery that a MeOH extract of Anabaena affinis strain VS-1 showed strong cytotoxicity to L1210 murine leukemia cells, and from that extract was isolated the compounds having the following structures, Compounds 1 and 2. These two compounds are believed to be responsible for the cytotoxicity of the marine organism. This is the first report of the isolation and characterization of pyrrolo[3,2-d] pyrimidine derivatives as biosynthetic products.
    Type: Grant
    Filed: March 30, 1993
    Date of Patent: October 29, 1996
    Inventors: Kenneth L. Rinehart, Wayne W. Carmichael, Michio Namikoshi
  • Rhizoxin esters and salts, their pharmaceutical use as anti-tumor agents
    Patent number: 4791128
    Abstract: Acylated derivatives of rhizoxin and of rhizoxin-2-ene may be prepared by reacting rhizoxin or rhizoxin-2-ene with an acid or reactive derivative thereof. They have excellent anti-tumor activity.
    Type: Grant
    Filed: January 11, 1988
    Date of Patent: December 13, 1988
    Assignee: Sankyo Company Limited
    Inventors: Shigenobu Okuda, Shigeo Iwasaki, Michio Namikoshi, Masao Arakawa, Fusaaki Shimizu