Patents by Inventor Michiyuki Matsuda

Michiyuki Matsuda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BETA-STRAND BRIDGE PEPTIDE
    Publication number: 20230174576
    Abstract: The present disclosure provides a novel bridge peptide. The present disclosure provides a bridge peptide comprising a bridge moiety and a peptide moiety, wherein position ? is tertiary or quaternary when the carbon at which the bridge moiety attaches to the peptide moiety is in position ?. The present disclosure provides a novel bridge peptide, particularly a bridge peptide resulting from stably bridging a peptide that does not possess a hydrogen bond to induce or maintain a secondary structure, e.g., a peptide having a ?-strand structure.
    Type: Application
    Filed: October 29, 2021
    Publication date: June 8, 2023
    Inventors: Kazuhiro Hayashi, Michiyuki Matsuda
  • Linker for unimolecular FRET biosensor based on principle of fluorescence resonance energy transfer
    Patent number: 9103790
    Abstract: A linker for a unimolecular FRET biosensor based on a principle of fluorescence resonance energy transfer, the linker including: a polypeptide containing 52 to 400 amino acids residues, wherein at least 45% of a total number of the amino acid residues are glycine, alanine, or both thereof, and at least 10% of the total number of the amino acid residues are alanine.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: August 11, 2015
    Assignee: KYOTO UNIVERSITY
    Inventors: Michiyuki Matsuda, Naoki Komatsu, Kazuhiro Aoki, Yuji Kamioka, Hiroko Yukinaga, Yoshie Inaoka, Atsuro Sakurai, Etsuko Kiyokawa, Kenta Sumiyama
  • Monitoring proteins for the activities of low-molecular- weight gtp-binding proteins
    Publication number: 20040053328
    Abstract: The present invention relates to monitoring proteins for the activity of low-molecular-weight GTP-binding proteins, genes encoding the proteins, expression vectors encoding the genes, cells and transgenic animals carrying the expression vectors, methods for measurement of the activity of low-molecular-weight GTP-binding proteins which use the proteins, and screening methods for the regulatory substances of low-molecular-weight GTP-binding proteins.
    Type: Application
    Filed: August 11, 2003
    Publication date: March 18, 2004
    Inventor: Michiyuki Matsuda
  • cDNA of dock 180 gene and dock180 protein
    Patent number: 5786453
    Abstract: The present invention provides a cDNA of DOCK180 gene, which has a nucleotide sequence of SEQ ID No: 1 and of which translation product binds to the proto-oncogene product CRK, a recombinant vector containing this cDNA, a DOCK180 protein expressed from the cDNA which has a amino acid sequence of SEQ ID No: 2, and an antibody to the DOCK180 protein. According to the present invention, It is possible to develop new diagnosing and therapeutic techniques using DOCK180 protein and antibody against the protein.
    Type: Grant
    Filed: November 17, 1997
    Date of Patent: July 28, 1998
    Assignee: Research Development Corporation of Japan
    Inventors: Michiyuki Matsuda, Takeshi Kurata
  • cDNA of DOCK180 gene and DOCK180 protein
    Patent number: 5777094
    Abstract: The present invention provides a cDNA of DOCK180 gene, which has a nucleotide sequence of SEQ ID NO: 1 and of which translation product binds to the proto-oncogene product CRK, a recombinant vector containing this cDNA, a DOCK180 protein expressed from the EDNA which has a amino acid sequence of SEQ ID NO: 2, and an antibody to the DOCK180 protein. According to the present invention, It is possible to develop new diagnosing and therapeutic techniques using DOCK180 protein and antibody against the protein.
    Type: Grant
    Filed: January 19, 1996
    Date of Patent: July 7, 1998
    Assignee: Research Development Corporation of Japan
    Inventors: Michiyuki Matsuda, Takeshi Kurata