Abstract: The present invention relates to a new compound useful as a modulator of melanocortin receptors. In particular, the present invention relates to a compound WS727713, a process for production of the compound by culturing, in a culture medium, a WS727713-producing strain belonging to Pseudonocardia and recovering the compound from a culture broth, a pharmaceutical composition containing the compound, and uses of the compound.

Abstract: The present invention relates to a new compound useful as a modulator of melanocortin receptors. In particular, the present invention relates to a compound WS727713, a process for production of the compound by culturing, in a culture medium, a WS727713-producing strain belonging to Pseudonocardia and recovering the compound from a culture broth, a pharmaceutical composition containing the compound, and uses of the compound.

Abstract: The present invention relates to a new compound useful as a modulator of melanocortin receptors.

Abstract: The present invention relates to a new compound useful as a modulator of melanocortin receptors.

Abstract: The present invention relates to a compound WS727713, useful as a modulator of melanocortin receptors, and a process for its production by culturing in a culture medium the actinomycetes strain of the genus Pseudonocardia, deposit number FERM BP-7570 and recovering the compound.

Abstract: The present invention relates to a new compound useful as a modulator of melanxocortin receptors.

Abstract: The present invention provides a new antimicrobial compound WF14573, and a process for producing WF14573 by (a) culturing a WF14573A and/or B-producing microorganism in a nutrient medium and recovering WF14573A and/or B from the resultant cultured broth or (b) deacylating WF14573A and/or B in the presence of a microbial substance which is capable of deacylating WF14573A and/or B. Also provided are an antimicrobial agent comprising WF14573 and carrier(s), a pharmaceutical composition comprising an effective amount of WF14573 and pharmaceutically acceptable carrier(s), a method for killing microorganisms by applying WF14573 to the microorganisms, and use of WF14573 for the treatment of infectious diseases caused by pathogenic microorganisms.

Abstract: This invention relates to new polypeptide compounds represented by the following formula (I): wherein R1 is as defined in the description or a salt thereof which have antimicrobial activities (especially, antifungal activities), inhibitory activity on &bgr;-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for the prophylactic and/or therapeutic treatment of infectious disease including Pneumocystis carinii infection (e.g., Pneumocystis carinii pneumonia) in a human being or an animal.

Abstract: New peptide compounds of the formula: ##STR1## wherein R.sup.1 is alkyl or aralkyl,R.sup.2 is amino(lower)alkyl or protected amino(lower)alkyl,R.sup.3 is hydroxy, protected hydroxy, amino or protected amino,R.sup.4 is hydroxy, orR.sup.3 and R.sup.4 are linked together to form --Z-- (in which --Z-- is --O-- or --NH--), andR.sup.5 is hydrogen or an amino protective group,R.sup.6 is hydroxy, orR.sup.5 and R.sup.6 are linked together to form bond,with proviso thatwhenR.sup.3 is hydroxy, protected hydroxy, amino or protected amino andR.sup.4 is hydroxy,then R.sup.5 and R.sup.6 are linked together to form bond,and a pharmaceutically acceptable salt thereof, which is useful as a medicament.