Patents by Inventor Mickaël Tanter
Mickaël Tanter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11940578Abstract: An imaging method including: a) acquiring N successive positron emission tomography (PET) low resolution images ?i and simultaneously, N successive Ultrafast Ultrasound Imaging (UUI) images Ui of a moving object; b) determining from each UUI image Ui, the motion vector fields Mi that corresponds to the spatio-temporal geometrical transformation of the motion of the object; c) obtaining a final estimated high resolution image H of the object by iterative determination of a high resolution image Hn+1 obtained by applying several correction iterations to a current estimated high resolution image Hn, n being the number of iterations, starting from an initial estimated high resolution image H1 of the object, each correction iteration including at least: i) warping the estimated high resolution image Hn using the motion vector fields Mi to determine a set of low resolution reference images Lni; ii) determining a differential image Di by difference between each PET image ?i and the corresponding low resolution reType: GrantFiled: January 28, 2021Date of Patent: March 26, 2024Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITÉ DE PARIS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS, ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARISInventors: Bertrand Tavitian, Mickaël Tanter, Mailyn Perez-Liva, Joaquin Lopez Herraiz, Jean Provost
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Publication number: 20240057969Abstract: An ultrasound probe holding device configured to attach to the head of an infant for transfontanellar imaging is disclosed, including a head pad configured to be in contact with the head of the infant and including a central opening, wherein the head pad is configured to receive an ultrasound probe; a pad squeezer, including a central opening and configured to cooperate with the head pad to allow an axial guidance of the head pad along a guidance axis substantially perpendicular to a surface tangent to the head of the infant; a device holder configured to be attached to the head of the infant and exert a downward force on the pad squeezer, along said guidance axis; and a repellent configured to exert a repellent force between the pad squeezer and the head pad when the device holder exerts the downward force on the pad squeezer.Type: ApplicationFiled: December 13, 2021Publication date: February 22, 2024Applicants: ICONEUS, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), Centre National de la Recherche Scientifique, ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARISInventors: Charlie Demene, Bruno-Felix Osmanski, Mickael Tanter, Jérôme Baranger, Olivier Baud
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Publication number: 20230330440Abstract: Devices and methods for reversibly stimulating neuronal cells in a subject. The devices include a module for generating ultrasounds at 4 MHz or more to stimulate neuronal cells expressing mechanosensitive channels with the ultrasounds. The methods include expressing mechanosensitive channels into neuronal cells and exposing the cells to ultrasounds at 4 MHz or more. Also, the use of the methods or devices for visual restoration in a subject.Type: ApplicationFiled: September 9, 2021Publication date: October 19, 2023Applicants: SORBONNE UNIVERSITE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE)Inventors: Serge PICAUD, Sara CADONI, José-Alain SAHEL, Mickaël TANTER, Charlie DEMENE
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Publication number: 20230309944Abstract: The invention relates to a method for determining at least one property of an object, the method comprising a step of: a) obtaining first data relative to the object by an ultrasound imaging technique imaging the object at a frame rate superior to 300 Hz, characterized in that the method further comprises a step of: b) obtaining second data relative to the object by imaging the object with at least one of a X-ray and a ?-ray, and c) determining the at least one property of the object based on the first data and the second data.Type: ApplicationFiled: June 7, 2023Publication date: October 5, 2023Inventors: Jean PROVOST, Anikitos GAROFALAKIS, Mathieu PERNOT, Mickaël TANTER, Bertrand TAVITIAN, Thomas VIEL
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Patent number: 11766242Abstract: A method for mapping fibrous media by propagation of ultrasound from a set transducers, wherein: a number of unfocused incident ultrasonic waves having different wavefronts are emitted; the signals reverberated by the medium toward each transducer are captured; coherent signals respectively corresponding, for each transducer, to contributions coming from different fictitious focal points in the medium are determined; and then the orientation of the fibers is determined by comparing a spatial coherence between said coherent signals, in a plurality of directions.Type: GrantFiled: July 16, 2014Date of Patent: September 26, 2023Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Mickaël Tanter, Mathias Fink, Mathieu Pernot, Clément Papadacci
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Publication number: 20230225698Abstract: The present invention relates to the field of ultrasounds and imagining of the coronary blood flow of the heart. Patients with coronary microvascular dysfunction (CMD) have poor prognostic with significantly higher rates of cardiovascular events, including hospitalization for heart failure, sudden cardiac death, and myocardial infarction (MI). Despite the urgent clinical need, there are no non-ionizing and non-invasive techniques available in clinic to directly visualize the coronary microvasculature and assess the local coronary microvascular system. Flow imaging remains a difficult task to perform in the heart because of the fast movements of this organ. In order to overcome the limitations of actual imaging methods for the coronary blood flow, the inventors proposed an ultrasound ultrafast imaging method that automatically detect the time periods in which the myocardium velocity is low and estimate the coronary flow velocity and the tissue velocity from the same data acquisition.Type: ApplicationFiled: April 13, 2021Publication date: July 20, 2023Inventors: Mathieu PERNOT, Mickael TANTER, Clément PAPADACCI, Oscar DEMEULENAERE
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Patent number: 11633199Abstract: An apparatus for treating vascular thrombosis with ultrasound, includes a therapeutic ultrasonic transducer, suitable for generating focused ultrasonic waves that propagate along an emission axis; an imaging ultrasonic transducer associated with the therapeutic transducer; a means for moving the focal spot of the therapeutic ultrasonic transducer along the emission axis with respect to the imaging transducer; a motorized mechanical system for translating the transducers along at least a first axis parallel to the emission axis and a second axis perpendicular to the first; and an electronic control system for driving the motorized mechanical system and the means for moving the focal spot of the therapeutic transducer.Type: GrantFiled: October 18, 2018Date of Patent: April 25, 2023Assignee: CARDIAWAVEInventors: Guillaume Goudot, Mathieu Pernot, Mickael Tanter, Michael Vion
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Patent number: 11617560Abstract: The present invention aims at improving the Doppler imaging of a biological sample comprising blood. For this, it is proposed a method for imaging a biological sample (10), the sample (10) comprising blood (14) comprising diffusors and solid tissue (16), the method comprising obtaining observation, each observation being characterized by a different point spread function associating a signal to each location of the region of interest, the signal comprising a first contribution representative of the diffusors of blood vessels within the location, a second contribution representative of the tissue diffusors and a third contribution representative of blood signal associated to blood diffusors outside of the location, and estimating, for each location, the blood flow by using a statistical analysis.Type: GrantFiled: September 15, 2017Date of Patent: April 4, 2023Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIME INDUSTRIELLES DE LA VILLE DE PARIS, UNIVERSITÉ PARIS CITÉ, SORBONNE UNIVERSITÉInventors: Zsolt Lenkei, Mathieu Pernot, Mickael Tanter, Thomas Deffieux
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Patent number: 11554386Abstract: An ultrasound imaging and therapy device includes an array of concentric annular ultrasound transducers, and an ultrasound imaging device situated inside an innermost transducer of the plurality of concentric annular ultrasound transducers, wherein it further comprises a mechanical linkage allowing a tilting movement of the array of concentric annular ultrasound transducers with respect to the ultrasound imaging device and in that the ultrasound imaging device protrudes in an axial direction from the array of concentric annular ultrasound transducers; whereby the ultrasound imaging device can be kept stationary and in direct or indirect contact with a patient's skin while the array of concentric annular ultrasound transducers is tilted so as to move a focal point of ultrasound waves generated by the concentric annular ultrasound transducers within an imaging region of the ultrasound imaging device.Type: GrantFiled: April 21, 2017Date of Patent: January 17, 2023Assignees: CARDIAWAVE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALEInventors: Mathieu Pernot, Michael Vion, Mickael Tanter
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Patent number: 11508261Abstract: The invention relates to a method for obtaining a numerical model, the numerical model associating at least one objective measurement to a subjective sensation, the method comprising the steps of: a) imaging the at least one area of the brain by using unfocused waves produced by a transcranial ultrasound probe (20), to obtain at least one acquired image of the activity of the area, b) evaluating a physical quantity representative of the activity of the at least one area based on the acquired images, to obtain at least one objective measurement, c) obtaining from the subject at least one numerical value representative of a subjective sensation, and d) determining the numerical model by using the obtained objective measurement and the obtained numerical value.Type: GrantFiled: September 23, 2016Date of Patent: November 22, 2022Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), Centre National de la recherche scientifique, Université Pierre et Marie Curie, Université Paris Diderot, ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARISInventors: Thomas Deffieux, Mickaël Tanter, Jean-Luc Gennisson, Zsolt Lenkei, Mathieu Pernot
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Publication number: 20220346748Abstract: Because of the increase of the obesity related diseases, it is desirable to be able to detect a fatty liver and quantify the content in fat for the fatty liver. Known methods are biopsy and magnetic resonance imaging. However, biopsy is an invasive method and magnetic resonance imaging is a complicated method to carry out. The inventors propose a new ultrasonic method which is more compliant with a regular control of the content in fat for the fatty liver for a subject. This method notably relies on a smart exploitation of the coherence properties of ultrasound pulses applied to the liver. This method has already been validated on sane subjects as providing accurate measurements, notably for fat content.Type: ApplicationFiled: September 25, 2020Publication date: November 3, 2022Inventors: Mathieu PERNOT, Thomas DEFFIEUX, Mickael TANTER, Clément PAPADACCI
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Publication number: 20220346749Abstract: Because of the increase of the obesity related diseases, it is desirable to be able to detect a fatty liver and quantify the content in fat for the fatty liver. Known methods are biopsy and magnetic resonance imaging. However, biopsy is an invasive method and magnetic resonance imaging is a complicated method to carry out. The inventors propose a new ultrasonic method, which is more compliant with a regular control of the content in fat for the fatty liver for a subject. This method notably relies on a smart exploitation of the coherence properties of ultrasound pulses applied to the liver. This method has already been validated on sane subjects as providing accurate measurements, notably for fat content.Type: ApplicationFiled: September 25, 2020Publication date: November 3, 2022Inventors: Mathieu PERNOT, Thomas DEFFIEUX, Mickael TANTER, Clément PAPADACCI
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Publication number: 20220273268Abstract: A cardiac device comprises a transmitter (10) arranged to transmit at least one wave, a probe (12) arranged to measure a shear wave caused by a wave coming from the transmitter (10), a detector (14) arranged to detect a systole phase in an electrocardiographic signal, and an estimator (16) arranged to determine, during at least one cardiac cycle, the propagation speed of a plurality of shear waves caused by the transmission of waves in several directions towards the heart of a patient, to determine using the detector (14) that which has a maximum propagation speed during the systole phase, and to derive an active cardiac stress response therefrom (160).Type: ApplicationFiled: July 29, 2020Publication date: September 1, 2022Inventors: Dominique Chapelle, Philippe Moireau, Mathieu Pernot, Mickaël Tanter
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Patent number: 11399804Abstract: A method for characterizing an anisotropic soft medium (C) including fibers and having an outer surface (1), by observing in different propagation directions, the propagation of a divergent shear wave from a central area (10) in the anisotropic soft medium. A propagation parameter of the shear wave is inferred therefrom in each of the propagation directions, and then a direction of the fibers of the anisotropic soft medium, a rheological elasticity parameter are determined in a direction perpendicular to the fibers and a rheological elasticity parameter in the direction of the fibers.Type: GrantFiled: January 12, 2015Date of Patent: August 2, 2022Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), ECOLE SUPRERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, UNIVERSITÉ PARIS DIDEROT—PARIS 7Inventors: Mickaël Tanter, Mathieu Pernot, Mathias Fink, Jean-Luc Gennisson
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Publication number: 20220039776Abstract: The invention concerns a multi-sensor brain detecting apparatus, the detecting apparatus being adapted to obtain two different physical values of a brain of a subject, the detecting apparatus comprising: a set of sensors comprising an ultrasound transducer adapted to produce ultrasound waves, a frame with a position with relation to the brain known with a stereotaxic precision, the frame being adapted to hold a sensor that can be positioned at a specific location by a user of the detecting apparatus without using a tool.Type: ApplicationFiled: October 21, 2021Publication date: February 10, 2022Inventors: Jean-Luc GENNISSON, Mickaël TANTER, Thomas DEFFIEUX, Mathieu PERNOT
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Patent number: 11234677Abstract: The invention concerns a detecting apparatus (12) comprising:—at least two sensors (24, 26, 28), with at least one sensor (24) being an ultrasound transducer adapted to produce ultrasound waves, and—a positioning device (16) defining several compartments (22), each compartment (22) being adapted to hold a sensor (24, 26, 28) and each compartment (22) being located at predetermined location, the positioning device (16) comprising a holder adapted to be fixed on the skull of a subject, the positioning device (16) being adapted to be maintained on the head of the subject using the holder.Type: GrantFiled: June 9, 2016Date of Patent: February 1, 2022Assignees: INSERM (Institut National de la Santé et de la Recherche Médicale), Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie (Paris 6), Université Paris Diderot—Pris 7, Ecole Superieure de Physique et de Chimie Industrielles de la Ville de ParisInventors: Jean-Luc Gennisson, Mickaël Tanter, Thomas Deffieux, Mathieu Pernot
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Publication number: 20210353439Abstract: Methods and systems are provided for decoding movement intentions using functional ultrasound (fUS) imaging of the brain. In one example, decoding movement intentions include determining a memory phase of a cognitive state of the brain, the memory phase between a gaze fixation phase and movement execution phase, and determining one or more movement intentions including one or more of intended effector (e.g., hand, eye) and intended direction (e.g., right, left) according to a machine learning algorithm trained to classify one or more movement intentions simultaneously.Type: ApplicationFiled: May 12, 2021Publication date: November 18, 2021Applicants: California Institute of Technology, INSERM (Institut National de la Santé et de la Recherche Médicale), CNRS-CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de ParisInventors: Sumner L Norman, David Maresca, Vasileios Christopoulos, Mikhail Shapiro, Richard A. Andersen, Mickael Tanter, Charlie Demene
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Patent number: 11141130Abstract: In order to obtain a predetermined ultrasonic wave field in a homogeneous internal part of a medium masked by an aberrating barrier, an ultrasonic lens is interposed between the emitting ultrasonic probe and the aberrating barrier. The ultrasonic lens is calculated by using a model of the medium comprising a mapping of ultrasonic wave propagation properties obtained from actual imaging of the medium such that when the ultrasound probe sends a predetermined ultrasonic wave, said predetermined wave generates the predetermined objective ultrasonic wave field in the medium.Type: GrantFiled: June 30, 2016Date of Patent: October 12, 2021Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MEDICALE)Inventors: Mickaël Tanter, Jean-François Aubry, Thomas Deffieux, Mathieu Pernot
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Publication number: 20210239863Abstract: An imaging method including: a) acquiring N successive positron emission tomography (PET) low resolution images ?i and simultaneously, N successive Ultrafast Ultrasound Imaging (UUI) images Ui of a moving object; b) determining from each UUI image Ui, the motion vector fields Mi that corresponds to the spatio-temporal geometrical transformation of the motion of the object; c) obtaining a final estimated high resolution image H of the object by iterative determination of a high resolution image Hn+1 obtained by applying several correction iterations to a current estimated high resolution image Hn, n being the number of iterations, starting from an initial estimated high resolution image H1 of the object, each correction iteration including at least: i) warping the estimated high resolution image Hn using the motion vector fields Mi to determine a set of low resolution reference images Lni; ii) determining a differential image Di by difference between each PET image ?i and the corresponding low resolution reType: ApplicationFiled: January 28, 2021Publication date: August 5, 2021Inventors: Bertrand TAVITIAN, Mickaël TANTER, Mailyn PEREZ-LIVA, Joaquin LOPEZ HERRAIZ, Jean PROVOST
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Publication number: 20210196295Abstract: An apparatus for treating vascular thrombosis with ultrasound, includes a therapeutic ultrasonic transducer, suitable for generating focused ultrasonic waves that propagate along an emission axis; an imaging ultrasonic transducer associated with the therapeutic transducer; a means for moving the focal spot of the therapeutic ultrasonic transducer along the emission axis with respect to the imaging transducer; a motorized mechanical system for translating the transducers along at least a first axis parallel to the emission axis and a second axis perpendicular to the first; and an electronic control system for driving the motorized mechanical system and the means for moving the focal spot of the therapeutic transducer.Type: ApplicationFiled: October 18, 2018Publication date: July 1, 2021Inventors: Guillaume GOUDOT, Mathieu PERNOT, Mickael TANTER, Michael VION