Patents by Inventor Micsunica Platica

Micsunica Platica has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PAR, a novel marker gene for breast and prostate cancers
    Patent number: 7510707
    Abstract: The present invention relates to a gene selectively expressed in malignant cells and associated with the development of androgen resistance in prostate cancer. Levels of the gene, termed “PAR” (for Prostate Androgen Regulated), its RNA transcript, and its protein product are all present at increased levels in malignant cells, such as breast cancer and prostate cancer cells. The present invention provides for PAR nucleic acid molecules and proteins, for antibodies that specifically bind to PAR proteins, and to methods for diagnosing and treating cancers that utilize such molecules.
    Type: Grant
    Filed: June 24, 2002
    Date of Patent: March 31, 2009
    Assignee: New York University Mt. Sinai School of Medicine
    Inventors: Micsunica Platica, Ovidu Platica, James F. Holland
  • PAR, a novel marker gene for breast and prostate cancers
    Publication number: 20030005471
    Abstract: The present invention relates to a gene selectively expressed in malignant cells and associated with the development of androgen resistance in prostate cancer. Levels of the gene, termed “PAR” (for Prostate Androgen Regulated), its RNA transcript, and its protein product are all present at increased levels in malignant cells, such as breast cancer and prostate cancer cells. The present invention provides for PAR nucleic acid molecules and proteins, for antibodies that specifically bind to PAR proteins, and to methods for diagnosing and treating cancers that utilize such molecules.
    Type: Application
    Filed: June 24, 2002
    Publication date: January 2, 2003
    Inventors: Micsunica Platica, Ovidu Platica, James F. Holland
  • Pituitary differentiaton factor and methods of use thereof
    Patent number: 5888817
    Abstract: The present invention is directed to pituitary differentiation factor (PDF), a pituitary factor that is capable of differentiating cells including breast cancer and prostatic cancer cells. Isolated nucleic acids encoding PDF and related vectors and host cells are also provided. Restoration of differentiating ability to malignantly transformed cells provides a modality of cancer therapy. The isolated and purified PDF of the invention is accordingly useful in the treatment of breast and prostatic cancer.
    Type: Grant
    Filed: November 25, 1997
    Date of Patent: March 30, 1999
    Assignee: The Mount Sinai School of Medicine
    Inventors: Micsunica Platica, Ovidiu Platica, James F. Holland
  • Pituitary differentiation factor and methods of use thereof
    Patent number: 5795740
    Abstract: The present invention is directed to pituitary differentiation factor (PDF), a pituitary factor that is capable of differentiating cells including breast cancer and prostatic cancer cells. Isolated nucleic acids encoding PDF and related vectors and host cells are also provided. Restoration of differentiating ability to malignantly transformed cells provides a modality of cancer therapy. The isolated and purified PDF of the invention is accordingly useful in the treatment of breast and prostatic cancer.
    Type: Grant
    Filed: July 9, 1997
    Date of Patent: August 18, 1998
    Assignee: Mount Sinai School of Medicine
    Inventors: Micsunica Platica, Ovidiu Platica, James F. Holland