Patents by Inventor Mie Kainoh

Mie Kainoh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060241132
    Abstract: Disclosed is the use of an adhesion molecule inhibitor that is effective in the prevention and treatment of inflammatory diseases caused by infiltration of leukocytes such as monocytes, lymphocytes and eosindphils, by inhibiting cell infiltration which mediates adhesion molecules, especially adhesion molecule VLA-4. Since the spiro acid derivatives according to the present invention are excellent in the effect of inhibiting cell adhesion via adhesion molecules, especially adhesion molecule VLA-4, they are useful as therapeutic drugs against various inflammatory diseases. For example, provided are the spiro derivative and the adhesion molecule inhibitor which includes as an active ingredient the spiro derivative as shown by the below formula (18).
    Type: Application
    Filed: March 19, 2003
    Publication date: October 26, 2006
    Applicant: Toray Industries, Inc. A Corporation of Japan
    Inventors: Takeshi Ishigaki, Koji Taniguchi, Aki Taniguchi, Mie Kainoh, Hiroyuki Meguro, Yoko Ishizaka
  • Patent number: 6919349
    Abstract: Disclosed are novel spiro derivatives and their medical uses, especially as adhesion molecule inhibitors useful for therapies of inflammatory diseases.
    Type: Grant
    Filed: September 25, 2001
    Date of Patent: July 19, 2005
    Assignee: Toray Industries, Inc.
    Inventors: Toshiya Takahashi, Takeshi Ishigaki, Miyuki Funahashi, Koji Taniguchi, Masayuki Kaneko, Mie Kainoh, Hiroyuki Meguro
  • Publication number: 20040087574
    Abstract: Disclosed are novel spiro derivatives and their medical uses, especially as adhesion molecule inhibitors useful for therapies of inflammatory diseases.
    Type: Application
    Filed: March 25, 2003
    Publication date: May 6, 2004
    Inventors: Toshiya Takahashi, Takeshi Ishigaki, Miyuki Funahashi, Koji Taniguchi, Masayuki Kaneko, Mie Kainoh, Hiroyuki Meguro
  • Publication number: 20040039040
    Abstract: Disclosed are novel urea derivatives and their medical uses, especially as adhesion molecule inhibitors useful for therapies of inflammatory diseases.
    Type: Application
    Filed: March 14, 2003
    Publication date: February 26, 2004
    Inventors: Toshiya Takahashi, Takeshi Ishigaki, Miyuki Funahashi, Koji Taniguchi, Masayuki Kaneko, Mie Kainoh, Hiroyuki Meguro
  • Patent number: 6511961
    Abstract: Novel cyclic peptides having VLA-4 adhesion inhibiting activity, and their application as therapeutic agents for inflammatory disease, for example allergic inflammatory disease, or hepatitis.
    Type: Grant
    Filed: July 9, 1999
    Date of Patent: January 28, 2003
    Assignee: Toray Industries, Inc.
    Inventors: Toshiya Takahashi, Nobuo Saito, Hideyuki Takeshige, Toshiaki Tanaka, Mie Kainoh
  • Patent number: 6340693
    Abstract: The present invention provides a protective agent for nervous system structural cells comprising a prostaglandin I derivative, preferably a prostaglandin I2 derivative, particularly beraplost, as an active component. This medicine exhibits excellent effects as a protective agent for nervous system structural cells, and is effective as an excellent agent for preventing or curing cerebrovascular disorder, cerebral nerve cell disorder, ischemic cerebral disorder, dementia, and peripheral nerve disorder due to diabetic or the like.
    Type: Grant
    Filed: February 16, 1999
    Date of Patent: January 22, 2002
    Assignee: Toray Industries, Inc.
    Inventors: Hajimu Kurumatani, Susumu Matsuda, Mie Kainoh