Abstract: The present invention provides an iontophoresis device with high administration efficient of a drug. An iontophoresis device, including an active electrode structure including: an electrode to which a positive electrical potential is applied; a drug holding part for holding a drug solution containing positively charged drug ions, the drug holding part being placed on a front side of the electrode; a cellulose-based resin film placed on a front side of the drug holding part or a complex film composed of a cation exchange membrane and a cellulose-based resin film placed on a front side of the cation exchange membrane, the complex film being placed on a front side of the drug holding part, in which the drug ions are administered through the cellulose-based resin film.

Abstract: A surface-modified plastic film, comprising: a surface layer composed of minute filamentous forms and/or granular forms consisting of a composition containing a resin and/or inorganic microparticles, on at least one major surface of a substrate plastic film. Preferably, the surface-modified plastic film is characterized in that the minute filamentous forms have a diameter of 100 ?m to 1 nm.

Abstract: A single cell comprising a fuel electrode, an air electrode, and an electrolytic layer or hollow layer interposed between those electrodes, or a fuel cell comprised of a stack of these single cells, wherein a supply port is formed on the fuel electrode side for supplying a hydrogen-based/oxygen-based mixed gas obtained by electrolyzing an electrolyte fluid by agitating and stirring and collecting the resulting gas; moreover the fuel electrode to which the hydrogen-based/oxygen-based mixed gas is supplied is gas-permeable. The hydrogen-based/oxygen-based mixed gas contains H, H2, H3, and/or HD, OH, 16O, and O2.

Abstract: The administration efficiency of a drug may be improved by establishing compatibility between the suppression of the release of a biological counter ion from a living body's biological interface and the maintenance of a good state of contact between each of a working electrode structure and a nonworking electrode structure and the biological interface. Coating films each composed of an external preparation containing: a hydrophilic polymer matrix agent; and an ion-exchange resin dispersed in the hydrophilic polymer matrix agent, or coating films each composed of an external preparation containing a hydrophilic polymer having an ion-exchange function are formed on the biological interface, and iontophoresis is performed through the coating films.

Abstract: The present invention provides an iontophoresis device with high administration efficient of a drug. An iontophoresis device, including an active electrode structure including: an electrode to which a positive electrical potential is applied; a drug holding part for holding a drug solution containing positively charged drug ions, the drug holding part being placed on a front side of the electrode; a cellulose-based resin film placed on a front side of the drug holding part or a complex film composed of a cation exchange membrane and a cellulose-based resin film placed on a front side of the cation exchange membrane, the complex film being placed on a front side of the drug holding part, in which the drug ions are administered through the cellulose-based resin film.