Patents by Inventor Mie Okano

Mie Okano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230295689
    Abstract: Provided is a nucleic acid detection apparatus including: a distribution unit configured to distribute a sample and a detection reagent to a plurality of individual independent separated compartments, the sample containing a target nucleic acid, and the detection reagent containing an effector protein, crRNA to be bound to the target nucleic acid, and a reporter molecule; an activation unit configured to activate the effector protein through binding of the crRNA to the target nucleic acid; a fluorescence generation unit configured to modify the reporter molecule with the activated effector protein to generate fluorescence; a fluorescence detection unit configured to detect the fluorescence; and an identification unit configured to determine, based on a detection result obtained with the fluorescence detection unit, a fluorescence intensity of each of the individual independent separated compartments, and to identify each of the individual independent separated compartments having a fluorescence intensity exce
    Type: Application
    Filed: April 5, 2023
    Publication date: September 21, 2023
    Inventors: MASATO MINAMI, TETSUYA YANO, YOJI YAMAMOTO, MIE OKANO, SATOSHI OGAWA, TAKUSHI ICHINOO
  • Publication number: 20220090174
    Abstract: A detection method for a target nucleic acid comprising: a first step of contacting a target nucleic acid with a first guide RNA and a first Cas protein; a second step of contacting the target nucleic acid with a second guide RNA and a second Cas protein; and a third step of detecting a complex comprising the target nucleic acid, the first guide RNA, the first Cas protein, the second guid RNA, and the second Cas protein, wherein, in the complex, the first guide RNA and the first Cas protein are bound to the first base sequence, and the second guide RNA and the second Cas protein are bound to the second base sequence.
    Type: Application
    Filed: September 8, 2021
    Publication date: March 24, 2022
    Inventors: Mie Okano, Yoji Yamamoto, Masato Minami, Tetsuya Yano
  • Publication number: 20200138413
    Abstract: An object information acquiring apparatus includes: an optical image acquiring unit which acquires an optical image obtained by optically capturing an image of an object on which a marker is arranged; a photoacoustic image acquiring unit which acquires a photoacoustic image derived from a photoacoustic wave generated from the object irradiated with light; and a superimposed image generating unit which generates a graphic on the basis of positional information of the marker in the optical image and which generates a superimposed image by superimposing the graphic onto the photoacoustic image.
    Type: Application
    Filed: October 30, 2019
    Publication date: May 7, 2020
    Inventors: Mie Okano, Kenichi Nagae
  • Patent number: 10288719
    Abstract: An object information acquiring apparatus, comprises a light irradiating unit configured to irradiate an object with light; a probe configured to receive an acoustic wave generated from the object and convert into an electrical signal; a characteristic information acquiring unit configured to acquire characteristic information relating to the object based on the electrical signal; an area information acquiring unit configured to acquire information relating to a reachable area of the light; a location detecting unit configured to acquire an operator location; and a determining unit configured to determine whether the operator location is in a first state where the operator location overlaps with the reachable area of the light or a second state where the operator location does not overlap with the reachable area of the light.
    Type: Grant
    Filed: February 7, 2017
    Date of Patent: May 14, 2019
    Assignee: CANON KABUSHIKI KAISHA
    Inventors: Mie Okano, Yohei Hashizume, Yasufumi Asao
  • Publication number: 20190105018
    Abstract: Employed is an information processing apparatus, comprising: an interpretation result acquiring unit configured to acquire a plurality of pieces of interpretation result information resulting from interpretations by a plurality of interpreters of a photoacoustic image originating from photoacoustic waves produced from an object that has been irradiated with light; an interpreter information acquiring unit configured to acquire interpreter information that is information pertaining to the plurality of interpreters; and an information processing unit configured to, based on the interpreter information, acquire information identifying each of the interpreters that performed interpretations corresponding respectively to the plurality of pieces of interpretation result information, and configured to, using this interpreter-identifying information, perform weighting of the plurality of pieces of interpretation result information.
    Type: Application
    Filed: October 3, 2018
    Publication date: April 11, 2019
    Inventors: Mie Okano, Kouichi Kato, Fumitaro Masaki
  • Patent number: 10227337
    Abstract: Provided is an evaluation probe capable of optically evaluating permeability of a substance through a central nervous system tissue. Also provided is an evaluation method for permeability of a substance through a central nervous system tissue using an evaluation probe for central nervous system permeability. Also provided is a screening method using an evaluation probe for central nervous system permeability. The evaluation probe for central nervous system permeability includes, as an active ingredient, at least one kind of compound represented by the following general formula (1).
    Type: Grant
    Filed: February 16, 2012
    Date of Patent: March 12, 2019
    Assignee: CANON KABUSHIKI KAISHA
    Inventors: Toshio Tanaka, Kohei Watanabe, Tsuyoshi Nomoto, Mie Okano, Taichi Shintou, Takeshi Miyazaki, Yuhei Nishimura, Yasuhito Shimada
  • Publication number: 20170242096
    Abstract: An object information acquiring apparatus, comprises a light irradiating unit configured to irradiate an object with light; a probe configured to receive an acoustic wave generated from the object and convert into an electrical signal; a characteristic information acquiring unit configured to acquire characteristic information relating to the object based on the electrical signal; an area information acquiring unit configured to acquire information relating to a reachable area of the light; a location detecting unit configured to acquire an operator location; and a determining unit configured to determine whether the operator location is in a first state where the operator location overlaps with the reachable area of the light or a second state where the operator location does not overlap with the reachable area of the light.
    Type: Application
    Filed: February 7, 2017
    Publication date: August 24, 2017
    Inventors: Mie Okano, Yohei Hashizume, Yasufumi Asao
  • Publication number: 20170055844
    Abstract: An apparatus according to the present invention includes: a conversion element for converting an acoustic wave generated from an object when irradiated with light, to a reception signal; a signal processing unit for acquiring specific information of the object using the reception signal; a status measuring unit for measuring a status of placement of the object; a determining unit for determining whether the object is placed at an appropriate position for a photoacoustic measurement using a measurement result of the status measuring unit; and a noticing unit for noticing a method of moving the object on the basis of a determination result of the determining unit.
    Type: Application
    Filed: August 22, 2016
    Publication date: March 2, 2017
    Inventors: Kohtaro Umezawa, Yohei Hashizume, Mie Okano, Yohei Motoki
  • Publication number: 20160361442
    Abstract: To provide a central nervous system tissue-labeling composition labeling the central nervous tissue system. Also, another object of the present invention is to provide a method for non-invasively labeling the central nervous tissue system. Further, another object of the present invention is to provide a screening method using the above central nervous system tissue-labeling composition. A central nervous system tissue-labeling composition containing, as an active ingredient, at least one of compounds represented by the general formula (1) or (7).
    Type: Application
    Filed: August 23, 2016
    Publication date: December 15, 2016
    Inventors: Kohei Watanabe, Taichi Shintou, Tsuyoshi Nomoto, Takeshi Miyazaki, Mie Okano, Toshio Tanaka, Yuhei Nishimura, Yasuhito Shimada
  • Patent number: 9228952
    Abstract: The present invention provides a hematopoietic stem cell identification probe.
    Type: Grant
    Filed: July 10, 2013
    Date of Patent: January 5, 2016
    Assignee: Canon Kabushiki Kaisha
    Inventors: Kohei Watanabe, Tsuyoshi Nomoto, Mie Okano, Taichi Shintou, Takeshi Miyazaki, Yasuhiko Tabata, Hiroshi Kohara
  • Publication number: 20140017722
    Abstract: The present invention provides a hematopoietic stem cell identification probe.
    Type: Application
    Filed: July 10, 2013
    Publication date: January 16, 2014
    Inventors: Kohei Watanabe, Tsuyoshi Nomoto, Mie Okano, Taichi Shintou, Takeshi Miyazaki, Yasuhiko Tabata, Hiroshi Kohara
  • Publication number: 20130280169
    Abstract: To provide a central nervous system tissue-labeling composition labeling the central nervous tissue system. Also, another object of the present invention is to provide a method for non-invasively labeling the central nervous tissue system. Further, another object of the present invention is to provide a screening method using the above central nervous system tissue-labeling composition. A central nervous system tissue-labeling composition containing, as an active ingredient, at least one of compounds represented by the general formula (1) or (7).
    Type: Application
    Filed: June 19, 2013
    Publication date: October 24, 2013
    Inventors: Kohei Watanabe, Taichi Shintou, Tsuyoshi Nomoto, Takeshi Miyazaki, Mie Okano, Toshio Tanaka, Yuhei Nishimura, Yasuhito Shimada
  • Publication number: 20120207683
    Abstract: Provided is an evaluation probe capable of optically evaluating permeability of a substance through a central nervous system tissue. Also provided is an evaluation method for permeability of a substance through a central nervous system tissue using an evaluation probe for central nervous system permeability. Also provided is a screening method using an evaluation probe for central nervous system permeability. The evaluation probe for central nervous system permeability includes, as an active ingredient, at least one kind of compound represented by the following general formula (1).
    Type: Application
    Filed: February 16, 2012
    Publication date: August 16, 2012
    Applicant: CANON KABUSHIKI KAISHA
    Inventors: Toshio Tanaka, Kohei Watanabe, Tsuyoshi Nomoto, Mie Okano, Taichi Shintou, Takeshi Miyazaki, Yuhei Nishimura, Yasuhito Shimada
  • Publication number: 20110189096
    Abstract: To provide a central nervous system tissue-labeling composition labeling the central nervous tissue system. Also, another object of the present invention is to provide a method for non-invasively labeling the central nervous tissue system. Further, another object of the present invention is to provide a screening method using the above central nervous system tissue-labeling composition. A central nervous system tissue-labeling composition containing, as an active ingredient, at least one of compounds represented by the general formula (1) or (7).
    Type: Application
    Filed: April 12, 2011
    Publication date: August 4, 2011
    Applicant: CANON KABUSHIKI KAISHA
    Inventors: Kohei Watanabe, Taichi Shintou, Tsuyoshi Nomoto, Takeshi Miyazaki, Mie Okano, Toshio Tanaka, Yuhei Nishimura, Yasuhito Shimada
  • Patent number: 7863059
    Abstract: A target substance detection method for detecting a target substance in a specimen, comprises the steps of contacting with a specimen a target substance detecting element comprised of a base, a metal structure and a first capturing body for capturing a target substance; contacting with the target substance detecting element a labeling material comprised of a labeling substance and a second capturing body for capturing a target substance; and acquiring an absorption spectrum (A) of the target substance detecting element contacted with the specimen and the labeling material, wherein the employed labeling substance is a substance that a slope of a tangent of an absorption spectrum (C) of the labeling substance at a peak wavelength (?z) of an absorption spectrum (B) of the target substance detecting element is larger than zero.
    Type: Grant
    Filed: May 16, 2008
    Date of Patent: January 4, 2011
    Assignee: Canon Kabushiki Kaisha
    Inventors: Mie Okano, Junta Yamamichi
  • Publication number: 20080227218
    Abstract: A target substance detection method for detecting a target substance in a specimen, comprises the steps of contacting with a specimen a target substance detecting element comprised of a base, a metal structure and a first capturing body for capturing a target substance; contacting with the target substance detecting element a labeling material comprised of a labeling substance and a second capturing body for capturing a target substance; and acquiring an absorption spectrum (A) of the target substance detecting element contacted with the specimen and the labeling material, wherein the employed labeling substance is a substance that a slope of a tangent of an absorption spectrum (C) of the labeling substance at a peak wavelength (?z) of an absorption spectrum (B) of the target substance detecting element is larger than zero.
    Type: Application
    Filed: May 16, 2008
    Publication date: September 18, 2008
    Applicant: CANON KABUSHIKI KAISHA
    Inventors: Mie Okano, Junta Yamamichi
  • Publication number: 20070210268
    Abstract: Two different kinds of fluids are sent to a flow path for measurement in which a plurality of detection sections are provided, transit time of consecutive fluid, following preceding fluid, at each detection unit is detected, and a flow speed of the fluid is found from time required for the consecutive fluid to move between the plurality of detection sections. The present invention provides a measuring apparatus which measures the flow speed and a rate of flow in the flow path with suppressing an influence from the external to the fluid thereby, and a measuring method using the measuring apparatus.
    Type: Application
    Filed: March 9, 2007
    Publication date: September 13, 2007
    Applicant: CANON KABUSHIKI KAISHA
    Inventors: Junta YAMAMICHI, Mie OKANO