Patents by Inventor Miguel A. Cruz

Miguel A. Cruz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of vimentin in the modulation of acute inflammation and thrombosis
    Patent number: 10695401
    Abstract: Embodiments of the disclosure include methods and compositions for treating or preventing acute inflammation using soluble vimentin. In specific embodiments, a vimentin derivative comprising the rod domain is utilized for treating or preventing any disease in which a decrease in leukocyte adhesion is therapeutic. In specific embodiments, a fragment of vimentin that comprises part or all of the rod domain is employed.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: June 30, 2020
    Assignee: Baylor College of Medicine
    Inventors: Fong Wilson Lam, Qi Da, Miguel A. Cruz
  • THE USE OF VIMENTIN IN THE MODULATION OF ACUTE INFLAMMATION AND THROMBOSIS
    Publication number: 20200061153
    Abstract: Embodiments of the disclosure include methods and compositions for treating or preventing acute inflammation using soluble vimentin. In specific embodiments, a vimentin derivative comprising the rod domain is utilized for treating or preventing any disease in which a decrease in leukocyte adhesion is therapeutic. In specific embodiments, a fragment of vimentin that comprises part or all of the rod domain is employed.
    Type: Application
    Filed: November 30, 2017
    Publication date: February 27, 2020
    Inventors: Fong Wilson Lam, Qi Da, Miguel A. Cruz
  • Treatment of medical condition with A2 domain of von willebrand factor
    Patent number: 7879793
    Abstract: The present invention is directed to methods for the prevention, treatment and/or diagnosis of a medical condition, such as sepsis, systemic inflammatory reaction syndrome, and/or thrombosis, for example. In particular, the method employs part or all of the A2 domain of von Willebrand factor. In certain cases, a recombinant A2 domain is utilized for the treatment of sepsis, systemic inflammatory reaction syndrome, and/or thrombosis, for example.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: February 1, 2011
    Assignee: Baylor College of Medicine
    Inventor: Miguel A. Cruz
  • TREATMENT OF MEDICAL CONDITION WITH A2 DOMAIN OF VON WILLEBRAND FACTOR
    Publication number: 20090118161
    Abstract: The present invention is directed to methods for the prevention, treatment and/or diagnosis of a medical condition, such as sepsis, systemic inflammatory reaction syndrome, and/or thrombosis, for example. In particular, the method employs part or all of the A2 domain of von Willebrand factor. In certain cases, a recombinant A2 domain is utilized for the treatment of sepsis, systemic inflammatory reaction syndrome, and/or thrombosis, for example.
    Type: Application
    Filed: October 18, 2007
    Publication date: May 7, 2009
    Inventor: Miguel A. Cruz