Patents by Inventor Miguel A. Estevez

Miguel A. Estevez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240101719
    Abstract: The present disclosure relates to method of obtaining high purity glucans, in particular yeast glucans with immunomodulatmy properties, including vaccine adjuvant properties for the use as adjuvant in vaccines.
    Type: Application
    Filed: February 11, 2022
    Publication date: March 28, 2024
    Inventors: Joao Cruz Fernandes, Maria Manuela Faria Amorim, Pedro Miguel Constante De Sousa, Diana Maria Tavares Valente, Joao Pedro Azevedo Silva, Christopher J. Paddon, Maria Manuela Estevez Pintado
  • Publication number: 20230000797
    Abstract: This invention provides methods utilizing ketamine for the treatment of motor disorders and/or side effects associated with certain medications used in the treatment of motor disorders. For example, in some embodiments, methods are provided for treating side effects associated with the administration of levodopa to a subject having Parkinson's disease, by administering a dose of ketamine or a pharmaceutically acceptable salt thereof. In particular, the invention provides methods for reducing dyskinesia associated with motor disorder (e.g.
    Type: Application
    Filed: August 29, 2022
    Publication date: January 5, 2023
    Inventors: Scott Sherman, Torsten Falk, Miguel Estevez
  • Patent number: 11426366
    Abstract: This invention provides methods utilizing ketamine for the treatment of motor disorders and/or side effects associated with certain medications used in the treatment of motor disorders. For example, in some embodiments, methods are provided for treating side effects associated with the administration of levodopa to a subject having Parkinson's disease, by administering a dose of ketamine or a pharmaceutically acceptable salt thereof. In particular, the invention provides methods for reducing dyskinesia associated with motor disorder (e.g., Parkinson's disease) treatments, and effective doses of ketamine or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: August 30, 2022
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSSITY OF ARIZONA
    Inventors: Scott Sherman, Torsten Falk, Miguel Estevez
  • Patent number: 11225339
    Abstract: An apparatus includes a thermally conductive interface assembly including a first component associated with a first interface surface and a second component associated with a second interface surface. The apparatus also includes a shape memory alloy component coupled to the thermally conductive interface assembly and configured to move one or more components of the thermally conductive interface assembly between a first state and a second state based on a temperature of the shape memory alloy component. In the first state, the first interface surface is in physical contact with the second interface surface, and in the second state, a gap is defined between the first interface surface and the second interface surface.
    Type: Grant
    Filed: June 26, 2020
    Date of Patent: January 18, 2022
    Assignee: THE BOEING COMPANY
    Inventors: Eric S. Mindock, James H. Mabe, Frederick Theodore Calkins, Abraham Naroll Gissen, Miguel A. Estevez
  • Publication number: 20200331639
    Abstract: An apparatus includes a thermally conductive interface assembly including a first component associated with a first interface surface and a second component associated with a second interface surface. The apparatus also includes a shape memory alloy component coupled to the thermally conductive interface assembly and configured to move one or more components of the thermally conductive interface assembly between a first state and a second state based on a temperature of the shape memory alloy component. In the first state, the first interface surface is in physical contact with the second interface surface, and in the second state, a gap is defined between the first interface surface and the second interface surface.
    Type: Application
    Filed: June 26, 2020
    Publication date: October 22, 2020
    Inventors: Eric S. Mindock, James H. Mabe, Frederick Theodore Calkins, Abraham NaroII Gissen, Miguel A. Estevez
  • Patent number: 10730645
    Abstract: An apparatus includes a thermally conductive interface assembly including a first component associated with a first interface surface and a second component associated with a second interface surface. The apparatus also includes a shape memory alloy component coupled to the thermally conductive interface assembly and configured to move one or more components of the thermally conductive interface assembly between a first state and a second state based on a temperature of the shape memory alloy component. In the first state, the first interface surface is in physical contact with the second interface surface, and in the second state, a gap is defined between the first interface surface and the second interface surface.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: August 4, 2020
    Assignee: THE BOEING COMPANY
    Inventors: Eric S. Mindock, James H. Mabe, Frederick Theodore Calkins, Abraham Naroll Gissen, Miguel A. Estevez
  • Patent number: 10717551
    Abstract: A spacecraft system includes a plurality of spacecraft in a stack. The stack has one or more layers, each layer includes at least two spacecraft, and each spacecraft is releasably coupled to one or more adjacent spacecraft in the stack. The spacecraft system also includes a controller configured to, for each layer, (i) cause the layer to release from the stack, and (ii) after the layer releases from the stack, cause the at least two spacecraft in the layer to release from each other.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: July 21, 2020
    Assignee: The Boeing Company
    Inventors: Miguel A. Estevez, Jason D. Flathom, Gary E. Lemke, Dennis Yoichi Nakasone, Christopher P. Volk, Elvis D. Silva
  • Publication number: 20200024010
    Abstract: In an example, a spacecraft system includes a plurality of spacecraft in a stack. The stack has one or more layers, each layer includes at least two spacecraft, and each spacecraft is releasably coupled to one or more adjacent spacecraft in the stack. The spacecraft system also includes a controller configured to, for each layer, (i) cause the layer to release from the stack, and (ii) after the layer releases from the stack, cause the at least two spacecraft in the layer to release from each other.
    Type: Application
    Filed: June 3, 2019
    Publication date: January 23, 2020
    Inventors: Miguel A. Estevez, Jason D. Flathom, Gary E. Lemke, Dennis Yoichi Nakasone, Christopher P. Volk, Elvis D. Silva
  • Patent number: 10411363
    Abstract: Foldable dipole array antennas are disclosed. A disclosed example apparatus includes a helical communication line of a dipole array antenna, and hinges spaced along the helical communication line. The apparatus also includes dipole branches operatively coupled to the helical communication line, where the dipole branches are to be moved, at the hinges, between deployed and un-deployed states.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: September 10, 2019
    Assignee: THE BOEING COMPANY
    Inventors: William J. Ceely, Tom M. Hikido, John E. Baldauf, Miguel A. Estevez
  • Patent number: 10351268
    Abstract: A spacecraft system includes a plurality of spacecraft in a stack. The stack has one or more layers, each layer includes at least two spacecraft, and each spacecraft is releasably coupled to one or more adjacent spacecraft in the stack. The spacecraft system also includes a controller configured to, for each layer, (i) cause the layer to release from the stack, and (ii) after the layer releases from the stack, cause the at least two spacecraft in the layer to release from each other.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: July 16, 2019
    Assignee: The Boeing Company
    Inventors: Miguel A. Estevez, Jason D. Flathom, Gary E. Lemke, Dennis Yoichi Nakasone, Christopher P. Volk, Elvis D. Silva
  • Publication number: 20190060254
    Abstract: This invention provides methods utilizing ketamine for the treatment of motor disorders and/or side effects associated with certain medications used in the treatment of motor disorders. For example, in some embodiments, methods are provided for treating side effects associated with the administration of levodopa to a subject having Parkinson's disease, by administering a dose of ketamine or a pharmaceutically acceptable salt thereof. In particular, the invention provides methods for reducing dyskinesia associated with motor disorder (e.g., Parkinson's disease) treatments, and effective doses of ketamine or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: May 12, 2016
    Publication date: February 28, 2019
    Inventors: Scott Sherman, Torsten Falk, Miguel Estevez
  • Publication number: 20180331433
    Abstract: Foldable dipole array antennas are disclosed. A disclosed example apparatus includes a helical communication line of a dipole array antenna, and hinges spaced along the helical communication line. The apparatus also includes dipole branches operatively coupled to the helical communication line, where the dipole branches are to be moved, at the hinges, between deployed and un-deployed states.
    Type: Application
    Filed: May 15, 2017
    Publication date: November 15, 2018
    Inventors: William J. Ceely, Tom M. Hikido, John E. Baldauf, Miguel A. Estevez
  • Publication number: 20180305043
    Abstract: An apparatus includes a thermally conductive interface assembly including a first component associated with a first interface surface and a second component associated with a second interface surface. The apparatus also includes a shape memory alloy component coupled to the thermally conductive interface assembly and configured to move one or more components of the thermally conductive interface assembly between a first state and a second state based on a temperature of the shape memory alloy component. In the first state, the first interface surface is in physical contact with the second interface surface, and in the second state, a gap is defined between the first interface surface and the second interface surface.
    Type: Application
    Filed: April 21, 2017
    Publication date: October 25, 2018
    Inventors: Eric S. Mindock, James H. Mabe, Frederick Theodore Calkins, Abraham NaroII Gissen, Miguel A. Estevez
  • Publication number: 20180162561
    Abstract: In an example, a spacecraft system includes a plurality of spacecraft in a stack. The stack has one or more layers, each layer includes at least two spacecraft, and each spacecraft is releasably coupled to one or more adjacent spacecraft in the stack. The spacecraft system also includes a controller configured to, for each layer, (i) cause the layer to release from the stack, and (ii) after the layer releases from the stack, cause the at least two spacecraft in the layer to release from each other.
    Type: Application
    Filed: December 8, 2016
    Publication date: June 14, 2018
    Inventors: Miguel A. Estevez, Jason D. Flathom, Gary E. Lemke, Dennis Yoichi Nakasone, Christopher P. Volk, Elvis D. Silva
  • Patent number: 7352916
    Abstract: A method to reduce coding artifacts within a discrete decoded picture includes a spatial and/or temporal filtering with respective filter characteristics dependent on an image quality value (Q). Preferably, the spatial filtering includes a deblocking filtering, wherein the deblocking filter operation decreases with an increasing image quality value (Q) and/or the deblocking filtering chooses an image quality value (Q) dependent weighting function for a pixel to be filtered according to an activity of both blocks to which common border said pixel belongs.
    Type: Grant
    Filed: August 11, 2005
    Date of Patent: April 1, 2008
    Assignee: Sony Deutschland GmbH
    Inventors: Miguel Estevez, Christian Unruh, Peter Wagner
  • Patent number: 7027661
    Abstract: A method to reduce coding artifacts within a discrete decoded picture includes a spatial and/or temporal filtering with respective filter characteristics dependent on an image quality value (Q). Preferably, the spatial filtering includes a deblocking filtering, wherein the deblocking filter operation decreases with an increasing image quality value (Q) and/or the deblocking filtering chooses a image quality value (Q) dependent weighting function for a pixel to be filtered according to an activity of both blocks to which common border said pixel belongs.
    Type: Grant
    Filed: November 26, 2001
    Date of Patent: April 11, 2006
    Assignee: SONY International (Europe) GmbH
    Inventors: Miguel Estevez, Christian Unruh, Peter Wagner
  • Patent number: 6996285
    Abstract: In a method to rate a discrete decoded picture (Pin) in respect to its quality a picture quality rating function (PQRF) is calculated on basis of an information about artefacts (ARI) within the discrete decoded picture and a coding information (CRI) which was used for discrete coding the picture. Preferrably, said method is used to determine a preferred discrete picture decoding and/or postprocessing method and/or to determine a preferred discrete picture encoding and/or pre-processing method.
    Type: Grant
    Filed: September 27, 2001
    Date of Patent: February 7, 2006
    Assignee: Sony International (Europe) GmbH
    Inventors: Christian Unruh, Miguel Estevez, Peter Wagner
  • Publication number: 20050265623
    Abstract: A method to reduce coding artifacts within a discrete decoded picture includes a spatial and/or temporal filtering with respective filter characteristics dependent on an image quality value (Q). Preferably, the spatial filtering includes a deblocking filtering, wherein the deblocking filter operation decreases with an increasing image quality value (Q) and/or the deblocking filtering chooses an image quality value (Q) dependent weighting function for a pixel to be filtered according to an activity of both blocks to which common border said pixel belongs.
    Type: Application
    Filed: August 11, 2005
    Publication date: December 1, 2005
    Inventors: Miguel Estevez, Christian Unruh, Peter Wagner
  • Publication number: 20020118399
    Abstract: A method to reduce coding artefacts within a discrete decoded picture includes a spatial and/or temporal filtering with respective filter characteristics dependent on an image quality value (Q). Preferrably, said spatial filtering includes a deblocking filtering, wherein the deblocking filter operation decreases with an increasing image quality value (Q) and/or said deblocking filtering chooses a image quality value (Q) dependent weighting function for a pixel to be filtered according to an activity of both blocks to which common border said pixel belongs.
    Type: Application
    Filed: November 26, 2001
    Publication date: August 29, 2002
    Inventors: Miguel Estevez, Christian Unruh, Peter Wagner
  • Publication number: 20020076119
    Abstract: In a method to rate a discrete decoded picture (Pin) in respect to its quality a picture quality rating function (PQRF) is calculated on basis of an information about artefacts (ARI) within the discrete decoded picture and a coding information (CRI) which was used for discrete coding the picture. Preferrably, said method is used to determine a preferred discrete picture decoding and/or postprocessing method and/or to determine a preferred discrete picture encoding and/or pre-processing method.
    Type: Application
    Filed: September 27, 2001
    Publication date: June 20, 2002
    Inventors: Christian Unruh, Miguel Estevez, Peter Wagner