Patents by Inventor Miguel A. Estevez
Miguel A. Estevez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240101719Abstract: The present disclosure relates to method of obtaining high purity glucans, in particular yeast glucans with immunomodulatmy properties, including vaccine adjuvant properties for the use as adjuvant in vaccines.Type: ApplicationFiled: February 11, 2022Publication date: March 28, 2024Inventors: Joao Cruz Fernandes, Maria Manuela Faria Amorim, Pedro Miguel Constante De Sousa, Diana Maria Tavares Valente, Joao Pedro Azevedo Silva, Christopher J. Paddon, Maria Manuela Estevez Pintado
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Publication number: 20230000797Abstract: This invention provides methods utilizing ketamine for the treatment of motor disorders and/or side effects associated with certain medications used in the treatment of motor disorders. For example, in some embodiments, methods are provided for treating side effects associated with the administration of levodopa to a subject having Parkinson's disease, by administering a dose of ketamine or a pharmaceutically acceptable salt thereof. In particular, the invention provides methods for reducing dyskinesia associated with motor disorder (e.g.Type: ApplicationFiled: August 29, 2022Publication date: January 5, 2023Inventors: Scott Sherman, Torsten Falk, Miguel Estevez
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Patent number: 11426366Abstract: This invention provides methods utilizing ketamine for the treatment of motor disorders and/or side effects associated with certain medications used in the treatment of motor disorders. For example, in some embodiments, methods are provided for treating side effects associated with the administration of levodopa to a subject having Parkinson's disease, by administering a dose of ketamine or a pharmaceutically acceptable salt thereof. In particular, the invention provides methods for reducing dyskinesia associated with motor disorder (e.g., Parkinson's disease) treatments, and effective doses of ketamine or a pharmaceutically acceptable salt thereof.Type: GrantFiled: May 12, 2016Date of Patent: August 30, 2022Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSSITY OF ARIZONAInventors: Scott Sherman, Torsten Falk, Miguel Estevez
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Patent number: 11225339Abstract: An apparatus includes a thermally conductive interface assembly including a first component associated with a first interface surface and a second component associated with a second interface surface. The apparatus also includes a shape memory alloy component coupled to the thermally conductive interface assembly and configured to move one or more components of the thermally conductive interface assembly between a first state and a second state based on a temperature of the shape memory alloy component. In the first state, the first interface surface is in physical contact with the second interface surface, and in the second state, a gap is defined between the first interface surface and the second interface surface.Type: GrantFiled: June 26, 2020Date of Patent: January 18, 2022Assignee: THE BOEING COMPANYInventors: Eric S. Mindock, James H. Mabe, Frederick Theodore Calkins, Abraham Naroll Gissen, Miguel A. Estevez
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Publication number: 20200331639Abstract: An apparatus includes a thermally conductive interface assembly including a first component associated with a first interface surface and a second component associated with a second interface surface. The apparatus also includes a shape memory alloy component coupled to the thermally conductive interface assembly and configured to move one or more components of the thermally conductive interface assembly between a first state and a second state based on a temperature of the shape memory alloy component. In the first state, the first interface surface is in physical contact with the second interface surface, and in the second state, a gap is defined between the first interface surface and the second interface surface.Type: ApplicationFiled: June 26, 2020Publication date: October 22, 2020Inventors: Eric S. Mindock, James H. Mabe, Frederick Theodore Calkins, Abraham NaroII Gissen, Miguel A. Estevez
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Patent number: 10730645Abstract: An apparatus includes a thermally conductive interface assembly including a first component associated with a first interface surface and a second component associated with a second interface surface. The apparatus also includes a shape memory alloy component coupled to the thermally conductive interface assembly and configured to move one or more components of the thermally conductive interface assembly between a first state and a second state based on a temperature of the shape memory alloy component. In the first state, the first interface surface is in physical contact with the second interface surface, and in the second state, a gap is defined between the first interface surface and the second interface surface.Type: GrantFiled: April 21, 2017Date of Patent: August 4, 2020Assignee: THE BOEING COMPANYInventors: Eric S. Mindock, James H. Mabe, Frederick Theodore Calkins, Abraham Naroll Gissen, Miguel A. Estevez
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Patent number: 10717551Abstract: A spacecraft system includes a plurality of spacecraft in a stack. The stack has one or more layers, each layer includes at least two spacecraft, and each spacecraft is releasably coupled to one or more adjacent spacecraft in the stack. The spacecraft system also includes a controller configured to, for each layer, (i) cause the layer to release from the stack, and (ii) after the layer releases from the stack, cause the at least two spacecraft in the layer to release from each other.Type: GrantFiled: June 3, 2019Date of Patent: July 21, 2020Assignee: The Boeing CompanyInventors: Miguel A. Estevez, Jason D. Flathom, Gary E. Lemke, Dennis Yoichi Nakasone, Christopher P. Volk, Elvis D. Silva
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Publication number: 20200024010Abstract: In an example, a spacecraft system includes a plurality of spacecraft in a stack. The stack has one or more layers, each layer includes at least two spacecraft, and each spacecraft is releasably coupled to one or more adjacent spacecraft in the stack. The spacecraft system also includes a controller configured to, for each layer, (i) cause the layer to release from the stack, and (ii) after the layer releases from the stack, cause the at least two spacecraft in the layer to release from each other.Type: ApplicationFiled: June 3, 2019Publication date: January 23, 2020Inventors: Miguel A. Estevez, Jason D. Flathom, Gary E. Lemke, Dennis Yoichi Nakasone, Christopher P. Volk, Elvis D. Silva
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Patent number: 10411363Abstract: Foldable dipole array antennas are disclosed. A disclosed example apparatus includes a helical communication line of a dipole array antenna, and hinges spaced along the helical communication line. The apparatus also includes dipole branches operatively coupled to the helical communication line, where the dipole branches are to be moved, at the hinges, between deployed and un-deployed states.Type: GrantFiled: May 15, 2017Date of Patent: September 10, 2019Assignee: THE BOEING COMPANYInventors: William J. Ceely, Tom M. Hikido, John E. Baldauf, Miguel A. Estevez
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Patent number: 10351268Abstract: A spacecraft system includes a plurality of spacecraft in a stack. The stack has one or more layers, each layer includes at least two spacecraft, and each spacecraft is releasably coupled to one or more adjacent spacecraft in the stack. The spacecraft system also includes a controller configured to, for each layer, (i) cause the layer to release from the stack, and (ii) after the layer releases from the stack, cause the at least two spacecraft in the layer to release from each other.Type: GrantFiled: December 8, 2016Date of Patent: July 16, 2019Assignee: The Boeing CompanyInventors: Miguel A. Estevez, Jason D. Flathom, Gary E. Lemke, Dennis Yoichi Nakasone, Christopher P. Volk, Elvis D. Silva
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Publication number: 20190060254Abstract: This invention provides methods utilizing ketamine for the treatment of motor disorders and/or side effects associated with certain medications used in the treatment of motor disorders. For example, in some embodiments, methods are provided for treating side effects associated with the administration of levodopa to a subject having Parkinson's disease, by administering a dose of ketamine or a pharmaceutically acceptable salt thereof. In particular, the invention provides methods for reducing dyskinesia associated with motor disorder (e.g., Parkinson's disease) treatments, and effective doses of ketamine or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: May 12, 2016Publication date: February 28, 2019Inventors: Scott Sherman, Torsten Falk, Miguel Estevez
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Publication number: 20180331433Abstract: Foldable dipole array antennas are disclosed. A disclosed example apparatus includes a helical communication line of a dipole array antenna, and hinges spaced along the helical communication line. The apparatus also includes dipole branches operatively coupled to the helical communication line, where the dipole branches are to be moved, at the hinges, between deployed and un-deployed states.Type: ApplicationFiled: May 15, 2017Publication date: November 15, 2018Inventors: William J. Ceely, Tom M. Hikido, John E. Baldauf, Miguel A. Estevez
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Publication number: 20180305043Abstract: An apparatus includes a thermally conductive interface assembly including a first component associated with a first interface surface and a second component associated with a second interface surface. The apparatus also includes a shape memory alloy component coupled to the thermally conductive interface assembly and configured to move one or more components of the thermally conductive interface assembly between a first state and a second state based on a temperature of the shape memory alloy component. In the first state, the first interface surface is in physical contact with the second interface surface, and in the second state, a gap is defined between the first interface surface and the second interface surface.Type: ApplicationFiled: April 21, 2017Publication date: October 25, 2018Inventors: Eric S. Mindock, James H. Mabe, Frederick Theodore Calkins, Abraham NaroII Gissen, Miguel A. Estevez
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Publication number: 20180162561Abstract: In an example, a spacecraft system includes a plurality of spacecraft in a stack. The stack has one or more layers, each layer includes at least two spacecraft, and each spacecraft is releasably coupled to one or more adjacent spacecraft in the stack. The spacecraft system also includes a controller configured to, for each layer, (i) cause the layer to release from the stack, and (ii) after the layer releases from the stack, cause the at least two spacecraft in the layer to release from each other.Type: ApplicationFiled: December 8, 2016Publication date: June 14, 2018Inventors: Miguel A. Estevez, Jason D. Flathom, Gary E. Lemke, Dennis Yoichi Nakasone, Christopher P. Volk, Elvis D. Silva
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Patent number: 7352916Abstract: A method to reduce coding artifacts within a discrete decoded picture includes a spatial and/or temporal filtering with respective filter characteristics dependent on an image quality value (Q). Preferably, the spatial filtering includes a deblocking filtering, wherein the deblocking filter operation decreases with an increasing image quality value (Q) and/or the deblocking filtering chooses an image quality value (Q) dependent weighting function for a pixel to be filtered according to an activity of both blocks to which common border said pixel belongs.Type: GrantFiled: August 11, 2005Date of Patent: April 1, 2008Assignee: Sony Deutschland GmbHInventors: Miguel Estevez, Christian Unruh, Peter Wagner
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Patent number: 7027661Abstract: A method to reduce coding artifacts within a discrete decoded picture includes a spatial and/or temporal filtering with respective filter characteristics dependent on an image quality value (Q). Preferably, the spatial filtering includes a deblocking filtering, wherein the deblocking filter operation decreases with an increasing image quality value (Q) and/or the deblocking filtering chooses a image quality value (Q) dependent weighting function for a pixel to be filtered according to an activity of both blocks to which common border said pixel belongs.Type: GrantFiled: November 26, 2001Date of Patent: April 11, 2006Assignee: SONY International (Europe) GmbHInventors: Miguel Estevez, Christian Unruh, Peter Wagner
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Patent number: 6996285Abstract: In a method to rate a discrete decoded picture (Pin) in respect to its quality a picture quality rating function (PQRF) is calculated on basis of an information about artefacts (ARI) within the discrete decoded picture and a coding information (CRI) which was used for discrete coding the picture. Preferrably, said method is used to determine a preferred discrete picture decoding and/or postprocessing method and/or to determine a preferred discrete picture encoding and/or pre-processing method.Type: GrantFiled: September 27, 2001Date of Patent: February 7, 2006Assignee: Sony International (Europe) GmbHInventors: Christian Unruh, Miguel Estevez, Peter Wagner
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Publication number: 20050265623Abstract: A method to reduce coding artifacts within a discrete decoded picture includes a spatial and/or temporal filtering with respective filter characteristics dependent on an image quality value (Q). Preferably, the spatial filtering includes a deblocking filtering, wherein the deblocking filter operation decreases with an increasing image quality value (Q) and/or the deblocking filtering chooses an image quality value (Q) dependent weighting function for a pixel to be filtered according to an activity of both blocks to which common border said pixel belongs.Type: ApplicationFiled: August 11, 2005Publication date: December 1, 2005Inventors: Miguel Estevez, Christian Unruh, Peter Wagner
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Publication number: 20020118399Abstract: A method to reduce coding artefacts within a discrete decoded picture includes a spatial and/or temporal filtering with respective filter characteristics dependent on an image quality value (Q). Preferrably, said spatial filtering includes a deblocking filtering, wherein the deblocking filter operation decreases with an increasing image quality value (Q) and/or said deblocking filtering chooses a image quality value (Q) dependent weighting function for a pixel to be filtered according to an activity of both blocks to which common border said pixel belongs.Type: ApplicationFiled: November 26, 2001Publication date: August 29, 2002Inventors: Miguel Estevez, Christian Unruh, Peter Wagner
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Publication number: 20020076119Abstract: In a method to rate a discrete decoded picture (Pin) in respect to its quality a picture quality rating function (PQRF) is calculated on basis of an information about artefacts (ARI) within the discrete decoded picture and a coding information (CRI) which was used for discrete coding the picture. Preferrably, said method is used to determine a preferred discrete picture decoding and/or postprocessing method and/or to determine a preferred discrete picture encoding and/or pre-processing method.Type: ApplicationFiled: September 27, 2001Publication date: June 20, 2002Inventors: Christian Unruh, Miguel Estevez, Peter Wagner