Patents by Inventor Miguel A Peinado

Miguel A Peinado has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for generating double stranded DNA libraries and sequencing methods for the identification of methylated cytosines
    Patent number: 11459602
    Abstract: The present invention relates to methods for the identification of methylated cytosines in a population of double stranded DNA molecules. The invention also relates to adapters and kits for synthesizing said adapters as well as to double stranded DNA libraries obtained by the methods of the invention.
    Type: Grant
    Filed: September 18, 2018
    Date of Patent: October 4, 2022
    Assignees: Fundadó Privada Institut De Medicina Predictiva I, Personalitzada Del Cáncer Llorenç Coll Mulet
    Inventors: Llorenç Coll Mulet, Miguel A. Peinado Morales
  • METHOD FOR GENERATING DOUBLE STRANDED DNA LIBRARIES AND SEQUENCING METHODS FOR THE IDENTIFICATION OF METHYLATED
    Publication number: 20220213533
    Abstract: The present invention relates to methods for the identification of methylated cytosines in a population of double stranded DNA molecules. The invention also relates to adapters and kits for synthesizing said adapters as well as to double stranded DNA libraries obtained by the methods of the invention.
    Type: Application
    Filed: December 7, 2021
    Publication date: July 7, 2022
    Applicants: Fundació Privada Institut De Medicina Predictiva I Personalitzada Del Cáncer
    Inventors: Llorenç Coll Mulet, Miguel A. Peinado Morales
  • METHOD FOR GENERATING DOUBLE STRANDED DNA LIBRARIES AND SEQUENCING METHODS FOR THE IDENTIFICATION OF METHYLATED CYTOSINES
    Publication number: 20190177776
    Abstract: The present invention relates to methods for the identification of methylated cytosines in a population of double stranded DNA molecules. The invention also relates to adapters and kits for synthesizing said adapters as well as to double stranded DNA libraries obtained by the methods of the invention.
    Type: Application
    Filed: September 18, 2018
    Publication date: June 13, 2019
    Applicant: Fundació Privada Institut De Medicina Predictiva I Personalitzada Del Cáncer
    Inventors: Llorenç Coll Mulet, Miguel A. Peinado Morales
  • Method for generating double stranded DNA libraries and sequencing methods for the identification of methylated cytosines
    Patent number: 10260087
    Abstract: The present invention relates to methods for the identification of methylated cytosines in a population of double stranded DNA molecules. The invention also relates to adapters and kits for synthesizing said adapters as well as to double stranded DNA libraries obtained by the methods of the invention.
    Type: Grant
    Filed: January 7, 2015
    Date of Patent: April 16, 2019
    Assignees: Fundació Privada Institut De Medicina Predictiva I Personalitzada Del Cáncer
    Inventors: Llorenç Coll Mulet, Miguel A. Peinado Morales
  • METHOD FOR GENERATING DOUBLE STRANDED DNA LIBRARIES AND SEQUENCING METHODS FOR THE IDENTIFICATION OF METHYLATED CYTOSINES
    Publication number: 20170002404
    Abstract: The present invention relates to methods for the identification of methylated cytosines in a population of double stranded DNA molecules. The invention also relates to adapters and kits for synthesizing said adapters as well as to double stranded DNA libraries obtained by the methods of the invention.
    Type: Application
    Filed: January 7, 2015
    Publication date: January 5, 2017
    Applicant: Fundacio Privada Institut De Medicina Predictiva I Personalitzada Del Cancer
    Inventors: Llorenç Coll Mulet, Miguel A. Peinado Morales
  • Method of diagnosing cancer and reagents therefor
    Patent number: 9157122
    Abstract: The present invention provides methods for diagnosis and monitoring the efficacy of treatment of a cancer. More particularly, the methods of the invention comprise detecting an enhanced degree of chromatin modification within Chromosome 2 of the human genome from about map position 2q14.1 to about map position 2q14.3 in a sample derived from a subject. The methods include detecting an enhanced level of methylation, or detecting an enhanced level of modification of a histone positioned within the chromatin within the region of about 2q14.1 to 2q14.3 of Chromosome 2. The methods also include detecting a modulated level of expression of a gene within the region of about 2q14.1 to 2q14.3 of Chromosome 2.
    Type: Grant
    Filed: November 11, 2005
    Date of Patent: October 13, 2015
    Assignee: Garvan Institute of Medical Research
    Inventors: Jordi Frigola Mas, Miguel A. Peinado, Susan Joy Clark
  • Method Of Diagnosing Cancer And Reagents Therefor
    Publication number: 20090042184
    Abstract: The present invention provides methods for diagnosis and monitoring the efficacy of treatment of a cancer. More particularly, the methods of the invention comprise detecting an enhanced degree of chromatin modification within Chromosome 2 of the human genome from about map position 2q14.1 to about map position 2q14.3 in a sample derived from a subject. The methods include detecting an enhanced level of methylation, or detecting an enhanced level of modification of a histone positioned within the chromatin within the region of about 2q14.1 to 2q14.3 of Chromosome 2. The methods also include detecting a modulated level of expression of a gene within the region of about 2q14.1 to 2q14.3 of Chromosome 2.
    Type: Application
    Filed: November 11, 2005
    Publication date: February 12, 2009
    Applicant: GARVAN INSTITUTE OF MEDICAL RESEARCH
    Inventors: Jordi Frigola Mas, Miguel A. Peinado, Susan Joy Clark
  • Genetic analysis of biological samples in arrayed expanded representations of their nucleic acids
    Publication number: 20040241696
    Abstract: The invention provides a method for the genetic analysis of biological samples after generation and expansion of subsets representing their nucleic acids. Each subset contains a characteristic but arbitrarily selected representation. Different subsets display complementary representations. The method is specially suitable for the study of gene expression profiles.
    Type: Application
    Filed: March 8, 2004
    Publication date: December 2, 2004
    Inventors: Miguel A Peinado, Rosa-Ana Risques, Elisenda Vendrell, Gabriel Capella, Monica Grau, Antonia Obrador, Gemma Tarafa, Victor Moreno, Xavier Sole, Elisabet Rosell-Vives, Marta Soler, Marc Masa Alvarez, Jaume Piulats