Abstract: A balun comprising a three-dimensional (3D) printed base. In one embodiment the balun further comprises a piece of copper tape adhered to an outer surface of the 3D printed base.

Abstract: Certain examples relate to a build material management system to transport build material from a collection to source to one of a plurality of storage tanks. The storage tank is determined by a controller that compares color of the build material measured by a color sensor with predetermined values. The controller routes the build material to the storage tank.

Abstract: The present invention relates to a novel class of tetrahydroisoquinoline compounds of formula I and to compositions comprising the same. The compounds and compositions of the present invention can be used as medicaments in the treatment of cancer.

Abstract: The present invention relates to a novel class of tetrahydroisoquinoline compounds of formula I and to compositions comprising the same. The compounds and compositions of the present invention can be used as medicaments in the treatment of cancer.

Abstract: A balun comprising a three-dimensional (3D) printed base. In one embodiment the balun further comprises a piece of copper tape adhered to an outer surface of the 3D printed base.

Abstract: Apparatus is described comprising a chamber (101), which further comprises an interior (130), a sensor (102), a fluid dispenser (103) and a controller (104). A 3D printed object can be disposed in the chamber (101). The sensor (102) is arranged to weigh the chamber (101) or the whole contents of the chamber (101). The fluid dispenser (103) is arranged to dispense fluid into the interior (130) of the chamber (101) and the controller (104) can determine the weight of the 3D printed object and control the fluid dispenser (103). A system and a non-transitory machine-readable storage medium encoded with instructions executable by a processor.

Abstract: The present invention relates to a novel class of pyridine-sulfonamide compounds and to compositions comprising the same. The compounds and compositions are useful as medicaments in the treatment of diseases responsive to inhibition of IL-1?, such as non-alcoholic steatohepatitis (NASH) and idiopathic pulmonary fibrosis (IPF).

Abstract: Certain examples relate to a storage tank loading system for loading powdered build material to a storage tank and generating a quality indicator. In these examples, the quality indicator may be generated by comparing a measured color with at least one predetermined threshold value, in these examples, the color of powdered build material is determined by a color sensor.

Abstract: Certain examples relate to a build material management system to transport build material from a collection to source to one of a plurality of storage tanks. The storage tank is determined by a controller that compares color of the build material measured by a color sensor with predetermined values. The controller routes the build material to the storage tank.

Abstract: An example of an apparatus is disclosed. The apparatus comprises a controller to obtain a desired quality level for an object to be printed based on an input. The controller is also to determine a ratio of a first build material and a second build material based on the desired quality level. The first build material is a higher quality build material than the second build material. The controller is further to prepare a mix of build material of the determined ratio to be used during generation of the object.

Abstract: The present invention relates to a novel class of tetrahydroisoquinoline compounds of formula I and to compositions comprising the same. The compounds and compositions of the present invention can be used as medicaments in the treatment of cancer.

Abstract: The invention provides compositions and methods for inhibiting the expression of the gene Snl6 in plants. Plants with inhibited expression of Snl6 have use in biofuel production, e.g., by increasing the amount of soluble sugar that can be extracted from the plant.

Abstract: p38 and JNK mitogen activated protein (MAP) kinase al losteric inhibitors are useful for treatment and/or prophylaxis of degenerative diseases of the nervous system. Compounds are used in a method for treatment and/or prophylaxis of the diseases and for use in therapy in general. The compounds bind to the region composed of amino acids at positions 170-199 of Mitogen-activated protein kinase 14 (Uniprot accession nr Q16539 or SEQ ID No 1) and/or Mitogen-activated protein kinase 11 (Uniprot accession nr Q15759 or SEQ ID No 2), SEQ ID NO.1 and SEQ ID NO.2 being the amino acid sequences of MAPK14 (?38?) and MAPK11 (?38?), respectively. The specific region composed of amino acids at positions 170-199 is herein disclosed as SEQ ID HO.4 for Mitogen-activated protein kinase 14 and SEQ ID NO.5 for Mitogen-activated protein kinase 11 and are believed to be new inhibitory binding sites.

Abstract: p38 and JNK mitogen activated protein (MAP) kinase al losteric inhibitors are useful for treatment and/or prophylaxis of degenerative diseases of the nervous system. Compounds are used in a method for treatment and/or prophylaxis of the diseases and for use in therapy in general. The compounds bind to the region composed of amino acids at positions 170-199 of Mitogen-activated protein kinase 14 (Uniprot accession nr Q16539 or SEQ ID No 1) and/or Mitogen-activated protein kinase 11 (Uniprot accession nr Q15759 or SEQ ID No 2), SEQ ID NO.1 and SEQ ID NO.2 being the amino acid sequences of MAPK14 (?38?) and MAPK11 (?38?), respectively. The specific region composed of amino acids at positions 170-199 is herein disclosed as SEQ ID HO.4 for Mitogen-activated protein kinase 14 and SEQ ID NO.5 for Mitogen-activated protein kinase 11 and are believed to be new inhibitory binding sites.

Abstract: A gaming machine has a cabinet with a cabinet frame, a display device, a light source, and a directional transmissible layer with directional light planes arranged parallel to and offset from each other. The display device is located within the cabinet frame and is configured to display a wagering game. The light source is positioned above the display device, within the cabinet frame, and emits direct light and indirect light towards a player position in front of the gaming machine. The indirect light reflects off the display device prior to reaching the player position, causing light glare towards the player position. To reduce or eliminate the light glare, the directional transmissible layer is placed at least in part over the light source such that the directional light planes are horizontally aligned with the display device to prevent at least some of the indirect light from reflecting off the display device.

Abstract: The present invention provides new p38 mitogen activated protein (MAP) kinase allosteric inhibitors which are useful for the treatment of p38 mediated diseases such as inflammatory diseases, e.g. rheumatoid arthritis, osteoarthritis, psoriatic arthritis, pain, musculoskeletal system inflammation and musculoskeletal system aging. The present invention thus provides compounds for use in a method for treatment of inflammatory diseases, as well as for use in therapy in general, wherein the compound binds to the region composed of amino acids at positions 170-199 of Mitogen-activated protein kinase 14 (Uniprot accession nr Q16539 or SEQ ID No 1) and/or Mitogen-activated protein kinase 11 (Uniprot accession nr Q15759 or SEQ ID No 2), SEQ ID NO. 1 and SEQ ID NO. 2 being the amino acid sequences of MAPK14 (p38cx) and MAPK11 (p38?), respectively. The specific region composed of amino acids at positions 170-199 is herein disclosed as SEQ ID NO. 4 for Mitogen-activated protein kinase 14 and SEQ ID NO.

Abstract: A gaming system comprises a wager input device for receiving at least one wager and a display for displaying a wagering game. The display includes an integrated image capture device for visually capturing objects proximate the display. The system further comprises at least one controller operative to (i) detect the presence of at least a first object proximate the display, (ii) cause the image capture device to visually capture the first object and create a stored image thereof, (iii) graphically integrate the stored image of the first object into the wagering game, and (iv) display one or more outcomes of the wagering game which include one or more symbols comprising at least a portion of the stored image.

Abstract: A gaming machine includes a cabinet having a topbox frame attached thereto and facing a player position in front of the gaming machine, and one or more display devices within the cabinet and configured to display a wagering game. The gaming machine further includes a tower light for indicating a status condition, and a conduit for mounting the tower light to the topbox frame. The conduit has a fixed end attached to the topbox frame and an adjustable end attached to the tower light. The adjustable end is movable to different positions to provide a line of sight for viewing the tower light.

Abstract: Gaming terminals, gaming machines, gaming systems, and methods of reconfiguring a display device are presented herein. A gaming terminal for playing a wagering game is disclosed, which includes an input device configured to receive a wager to play the wagering game, a cabinet, and a display device operatively mounted to the cabinet. The display device has an electronic graphical display screen that is operable to dynamically display information related to the wagering game. The display screen is configured to physically change shape and/or size.

Abstract: A gaming machine includes a cabinet having a topbox frame attached thereto and facing a player position in front of the gaming machine, and one or more display devices within the cabinet and configured to display a wagering game. The gaming machine further includes a tower light for indicating a status condition, and a conduit for mounting the tower light to the topbox frame. The conduit has a fixed end attached to the topbox frame and an adjustable end attached to the tower light. The adjustable end is movable to different positions to provide a line of sight for viewing the tower light.