Abstract: Disclosed herein is a method for enhancing adoptively transferred autologous or allogeneic immune effector cells (T cells) in patients who are HLA-C1+. In some embodiments, the method involves ablating KIR2DL2 expression in the T cells prior to adoptive transfer. In some embodiments, the T cells are further engineered to express a CAR. Therefore, disclosed herein are enhanced CAR-T cells that are engineered to have ablated KIR2DL2 expression or activity.

Abstract: A system is provided to validate a computer processor. The system includes a computing system configured to obtain core dump data including executable instructions corresponding to a code stored in a legacy processor. An instruction-level simulator is installed in the computing system and is configured to simulate the executable instructions to generate a plurality of instruction traces. The system further includes a pre-silicon chip model simulator configured to execute the instruction traces to generate performance data. The computer processor is verified based at least in part on the performance data.

Abstract: A computing system includes a core system and an uncore system. The core system includes a packet generator unit configured to generate a data packet having a plurality of bytes defining a target packet size, and to output a first byte among the plurality of bytes at a packet delivery start time. The uncore system includes an input/output (I/O) bridge configured to connect an I/O component to the core system, and a packet monitor unit configured to monitor the bytes delivered from the packet generator unit to the I/O component. The packet monitor unit further determines a packet delivery end time after detecting a last byte of the data packet. The computing system determines a latency attributed to the uncore system and the I/O bridge based on the packet delivery start time and the packet delivery end time.

Abstract: A system is provided to validate a computer processor. The system includes a computing system configured to obtain core dump data including executable instructions corresponding to a code stored in a legacy processor. An instruction-level simulator is installed in the computing system and is configured to simulate the executable instructions to generate a plurality of instruction traces. The system further includes a pre-silicon chip model simulator configured to execute the instruction traces to generate performance data. The computer processor is verified based at least in part on the performance data.

Abstract: A computing system includes a core system and an uncore system. The core system includes a packet generator unit configured to generate a data packet having a plurality of bytes defining a target packet size, and to output a first byte among the plurality of bytes at a packet delivery start time. The uncore system includes an input/output (I/O) bridge configured to connect an I/O component to the core system, and a packet monitor unit configured to monitor the bytes delivered from the packet generator unit to the I/O component. The packet monitor unit further determines a packet delivery end time after detecting a last byte of the data packet. The computing system determines a latency attributed to the uncore system and the I/O bridge based on the packet delivery start time and the packet delivery end time.

Abstract: The invention relates to a piezoresistive textile sensor for detecting the heart and respiratory rate, comprising a lower textile layer whereon a conductive ink or paste is deposited such that first conductive strips are defined, said lower textile layer being joined to a second piezoresistive textile layer whereon a second conductive strip is arranged, to which an upper textile layer is then joined, on which conductive inks and/or pastes can be deposited, said piezoresistive textile sensor being used in a system for detecting the heart and/or respiratory rate.

Abstract: Example implementations relate to PRNU suppression. For example, PRNU suppression may include performing a calibration surface PRNU characterization using a scanning system, performing a document-based PRNU characterization using the scanning system, and determining a correction function for PRNU suppression for the scanning system based on the calibration surface PRNU characterization and the document-based PRNU characterization.

Abstract: In one example, a document scanner having a document-receiving platen. The platen includes a plurality of alignment patterns disposed on the platen at known positions in a coordinate system. The scanner includes overlapping staggered scan bars disposed adjacent the platen, each scan bar fixed at a position to image a one-dimensional slice of a corresponding one of the alignment patterns. The scanner further includes a controller to determine, from the imaged slice, X and Y coordinates of each corresponding scan bar within the coordinate system.

Abstract: According to an example, an apparatus for controlling a media scan operation may include a first scan module to scan a section of a media, a tracking mechanism to track the media as the media is moved past the first scan module, and a controller. The controller may receive signals corresponding to the media movement from the tracking mechanism, determine, based upon the received signals, a current position of the media, and vary a timing at which the first scan module collects a scan of the section of the media based upon the determined current position of the media.

Abstract: Example implementations relate to PRNU suppression. For example, PRNU suppression may include performing a calibration surface PRNU characterization using a scanning system, performing a document-based PRNU characterization using the scanning system, and determining a correction function for PRNU suppression for the scanning system based on the calibration surface PRNU characterization and the document-based PRNU characterization.

Abstract: A dough proofing apparatus includes a proofing chamber for holding dough during proofing operations and having a door for accessing the proofing chamber. An air duct assembly includes at least one inlet opening and at least one fan for drawing in air from the proofing chamber. At least one heating element is located within the air duct assembly for heating the air and a flow path for delivering the heated air back to the proofing chamber. A vent chamber is divided into an exhaust side and an intake side, the exhaust side fluidly connected to the air duct assembly, the intake side fluidly connected to the proofing chamber.

Abstract: According to an example, an apparatus for controlling a media scan operation may include a first scan module to scan a section of a media, a tracking mechanism to track the media as the media is moved past the first scan module, and a controller. The controller may receive signals corresponding to the media movement from the tracking mechanism, determine, based upon the received signals, a current position of the media, and vary a timing at which the first scan module collects a scan of the section of the media based upon the determined current position of the media.

Abstract: The combination of gabapentin with lysine clonixinate (CLG) makes it possible to relieve neuropathic pain caused both by diabetic neuropathy and by an injury to the nerve. The CLG combination produces a synergy in the antiallodynic effect, when the allodynia has been generated by direct mechanical damage to nervous tissue or when it has been produced as a result of a diabetic pathology. The therapeutic effect of the CLG combination is 3 to 11 times greater than the effect of each of the drugs separately. The CLG combination is safe, because it shows no adverse effects on motor activity or alterations in neurological parameters nor damage to the liver or kidney.

Abstract: A wired textile control and power supply system as a connection interface between a smart telephone (1) and an electronic textile (3), the connection interface system is a completely textile Universal Serial Bus (USB) On The Go (OTG) connection interface and is composed of textile circuitry and which comprises: (2a) a harmonized standard textile AB USB micro-connector from the mobile telephony industry and is connected (2b) to a textile cable which produces the USB OTG exchange of power supply and control, (2c) optionally USB textile circuitry for signal conditioning and (2d) a control and power supply connection cable to the electronic textile (3). The proposed invention does not require the additional electronics of a control system dedicated to the electronic textile, which makes it simpler, more comfortable and economic than any other alternative for communication between smart mobile telephone devices and electronic textiles.

Abstract: In one example, a document scanner having a document-receiving platen. The platen includes a plurality of alignment patterns disposed on the platen at known positions in a coordinate system. The scanner includes overlapping staggered scan bars disposed adjacent the platen, each scan bar fixed at a position to image a one-dimensional slice of a corresponding one of the alignment patterns. The scanner further includes a controller to determine, from the imaged slice, X and Y coordinates of each corresponding scan bar within the coordinate system.

Abstract: The combination of gabapentin with lysine clonixinate (CLG) makes it possible to relieve neuropathic pain caused both by diabetic neuropathy and by an injury to the nerve. The CLG combination produces a synergy in the antiallodynic effect, when the allodynia has been generated by direct mechanical damage to nervous tissue or when it has been produced as a result of a diabetic pathology. The therapeutic effect of the CLG combination is 3 to 11 times greater than the effect of each of the drugs separately. The CLG combination is safe, because it shows no adverse effects on motor activity or alterations in neurological parameters nor damage to the liver or kidney.

Abstract: The invention relates to a piezoresistive textile sensor for detecting the heart and respiratory rate, comprising a lower textile layer whereon a conductive ink or paste is deposited such that first conductive strips are defined, said lower textile layer being joined to a second piezoresistive textile layer whereon a second conductive strip is arranged, to which an upper textile layer is then joined, on which conductive inks and/or pastes can be deposited, said piezoresistive textile sensor being used in a system for detecting the heart and/or respiratory rate.

Abstract: A dough proofing apparatus includes a proofing chamber for holding dough during proofing operations and having a door for accessing the proofing chamber. An air duct assembly includes at least one inlet opening and at least one fan for drawing in air from the proofing chamber. At least one heating element is located within the air duct assembly for heating the air and a flow path for delivering the heated air back to the proofing chamber. A vent chamber is divided into an exhaust side and an intake side, the exhaust side fluidly connected to the air duct assembly, the intake side fluidly connected to the proofing chamber.

Abstract: The invention relates to a large-area extensible pressure sensor for textile surfaces, of the type comprising a support on which a conductive ink is printed which can transmit a printed electrical signal by any known printing technique. More specifically, the pressure sensor is characterized in that said support is flexible, extensible and elastic, and a plurality of main tracks of extensible and elastic conductive ink or paste are printed on said support; on said plurality of main tracks a plurality of piezoresistive paste or ink depositions acting as pressure sensing points are printed, and each of these depositions are linked to a secondary extensible and elastic conductive ink or paste track, which is also printed on said support, resulting in all tracks, primary or secondary, being connected to a control system without crossing each other.

Abstract: A restraining system for connecting a belled end of a female pipe to a spigot end of a male pipe is disclosed. The system includes a ring-shaped casing having circumferential grooves separated by an abutment surface. One or more restraining rings or members are disposed in the grooves so as to contact both the casing and the outer surfaces of the male and female pipes. The one or more restraining rings restrain the pipes from moving away from each other when the system is pressurized.