Patents by Inventor Miguel Soares
Miguel Soares has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11692940Abstract: The present invention is enclosed in the area of machine learning, in particular machine learning for the analysis of High or Super-resolution spectroscopic data, which typically comprises analysis of highly complex samples/mixtures of substances and/or data with low resolution, for instance Laser-Induced Breakdown Spectroscopy (LIBS). It is an object of the present invention a method of computational self-learning for characterization of one or more constituents in a sample, from electromagnetic spectral information of such sample, which changes the paradigm associated with prior art methods, by using only sub-optical spectral information, i.e., obtaining the resolution of the spectral information and thereby be able to extract spectral lines—thus determining a spectral line position—from such spectral information, hence avoiding all the uncertainty associated with pixel based methods. It is also an object of the present invention a computational apparatus configured to implement such method.Type: GrantFiled: July 31, 2019Date of Patent: July 4, 2023Assignee: INESC TEC—Instituto de Engenharia de Sistemas e Computadores, Tecnologia e CiênciaInventors: Rui Miguel Da Costa Martins, Pedro Alberto Da Silva Jorge, Eduardo Alexander Pereira Silva, José Miguel Soares De Almeida, Alfredo Manuel De Oliveira Martins
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Patent number: 11254575Abstract: The present invention relates to a process, reactor and system to produce self-standing two-dimensional nanostructures, using a microwave-excited plasma environment. The process is based on injecting, into a reactor, a mixture of gases and precursors in stream regime. The stream is subjected to a surface wave electric field, excited by the use of microwave power which is introduced into a field applicator, generating high energy density plasmas, that break the precursors into its atomic and/or molecular constituents. The system comprises a plasma reactor with a surface wave launching zone, a transient zone with a progressively increasing cross-sectional area, and a nucleation zone. The plasma reactor together with an infrared radiation source provides a controlled adjustment of the spatial gradients, of the temperature and the gas stream velocity.Type: GrantFiled: May 11, 2017Date of Patent: February 22, 2022Assignee: INSTITUTO SUPERIOR TÉCNICOInventors: Elena Stefanova Tatarova, Julio Paulo Dos Santos Duarte Vieira Henriques, Luis Paulo Da Mota Capitao Lemos Alves, Bruno Miguel Soares Goncalves
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Publication number: 20220033872Abstract: The present disclosure relates to a portable device for collecting and/or concentrating in situ plankton microbiome, configured for submersion in water. The device herein disclosed is a compact and low-cost autonomous biosampler, with the ability to yield DNA samples for later genomic analysis.Type: ApplicationFiled: November 30, 2019Publication date: February 3, 2022Inventors: Catarina MAGALHÃES, Ana Paula MUCHA, Hugo Manuel DA SILVA RIBEiRO, Maria Fátima CARVALHO, Maria Paola TOMASINO, Marisa ALMEIDA, Sandra RAMOS, Alfredo Manuel DE OLIVEIRA MARTINS, André Miguel PINHEIRO DIAS, Eduardo Alexandre PEREIRA DA SILVA, José Miguel SOARES DE ALMEIDA, Marco MOTA GONÇALVES, Maurício Miguel DE OLIVEIRA GUEDES, Nuno Alexandre NETO DIAS
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Publication number: 20210270744Abstract: The present invention is enclosed in the area of machine learning, in particular machine learning for the analysis of High or Super-resolution spectroscopic data, which typically comprises analysis of highly complex samples/mixtures of substances and/or data with low resolution, for instance Laser-Induced Breakdown Spectroscopy (LIBS). It is an object of the present invention a method of computational self-learning for characterization of one or more constituents in a sample, from electromagnetic spectral information of such sample, which changes the paradigm associated with prior art methods, by using only sub-optical spectral information, i.e., obtaining the resolution of the spectral information and thereby be able to extract spectral lines—thus determining a spectral line position—from such spectral information, hence avoiding all the uncertainty associated with pixel based methods. It is also an object of the present invention a computational apparatus configured to implement such method.Type: ApplicationFiled: July 31, 2019Publication date: September 2, 2021Inventors: Rui Miguel DA COSTA MARTINS, Pedro Alberto DASILVA JORGE, Eduardo Alexander PEREIRA SILVA, José Miguel SOARES DE ALMEIDA, Alfredo Manuel DE OLIVEIRA MARTINS
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Publication number: 20200123010Abstract: The present invention relates to a process, reactor and system to produce self-standing two-dimensional nanostructures, using a microwave-excited plasma environment. The process is based on injecting, into a reactor, a mixture of gases and precursors in stream regime. The stream is subjected to a surface wave electric field, excited by the use of microwave power which is introduced into a field applicator, generating high energy density plasmas, that break the precursors into its atomic and/or molecular constituents. The system comprises a plasma reactor with a surface wave launching zone, a transient zone with a progressively increasing cross-sectional area, and a nucleation zone. The plasma reactor together with an infrared radiation source provides a controlled adjustment of the spatial gradients, of the temperature and the gas stream velocity.Type: ApplicationFiled: May 11, 2017Publication date: April 23, 2020Inventors: ELENA STEFANOVA TATAROVA, Julio Paulo Dos Santos Duarte Vieira Henriques, Luis Paulo Da Mota Capitao Lemos Alves, Bruno Miguel Soares Goncalves
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Coordinating injector-valve switching with pump-stroke timing to mitigate effects of pressure pulses
Patent number: 9523662Abstract: A liquid chromatography system includes an autosampler with an injector valve by which a sample at low pressure within a sample loop is introduced into a high-pressure solvent mixture stream. A solvent delivery system includes a pump in fluidic communication with the injector valve of the autosampler to deliver the solvent mixture stream thereto. The solvent delivery system further comprises a processor that calculates a number of strokes of the pump needed to deliver the solvent mixture stream to the injector valve of the autosampler. The processor counts strokes of the pump during delivery of the solvent mixture stream. In response to a stroke count equaling the calculated number of strokes, the processor signals the autosampler to switch the injector valve to introduce the sample to the solvent mixture stream during a pump transfer period within which the pump performs pressure control to compensate for a drop in pressure.Type: GrantFiled: November 11, 2010Date of Patent: December 20, 2016Assignee: WATERS TECHNOLOGIES CORPORATIONInventors: John Heden, John Lamoureux, Miguel Soares, Guo-Zhong Li -
Patent number: 9519291Abstract: A liquid chromatography system includes an autosampler that prepares a sample for introduction to a solvent stream and a solvent delivery system that delivers a solvent stream to the autosampler. Delivery of the solvent stream occurs in parallel with the autosampler's pre-injection operations. The autosampler starts pre-injection operations to make the sample ready for injection into the mixture stream, and the solvent delivery system starts delivery of a solvent stream to the autosampler. The start of the solvent stream delivery is coordinated with the start of the pre-injection operations such that the solvent stream arrives at the autosampler approximately coincident with when the autosampler completes the pre-injection operations, making the sample ready for injection.Type: GrantFiled: November 11, 2010Date of Patent: December 13, 2016Assignee: WATERS TECHNOLOGIES CORPORATIONInventors: John Heden, John Lamoureux, Miguel Soares, Guo-Zhong Li
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Patent number: 9289768Abstract: Described is an apparatus for reducing a temperature variation of a liquid chromatography sample. A tray drive using at least one of linear or rotational motion moves a sample tray along a path inside a sample compartment of the liquid chromatography system. A control module coordinates the movement of the sample tray by the tray drive and the movement of a sample needle by a needle drive so that any sample in the sample tray can be injected into the mobile phase of the system during a sample load operation. The tray drive is also used to move the sample tray along the path during a temperature averaging period when no loading occurs. Differences in sample temperatures due to variations in the air temperature at different locations inside the sample compartment are reduced, leading to more accurate and repeatable chromatographic measurement results.Type: GrantFiled: January 11, 2011Date of Patent: March 22, 2016Assignee: Waters Technologies CorporationInventors: Joshua A. Shreve, James E. Usowicz, Miguel Soares
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Publication number: 20130019695Abstract: Described is an apparatus for reducing a temperature variation of a liquid chromatography sample. A tray drive using at least one of linear or rotational motion moves a sample tray along a path inside a sample compartment of the liquid chromatography system. A control module coordinates the movement of the sample tray by the tray drive and the movement of a sample needle by a needle drive so that any sample in the sample tray can be injected into the mobile phase of the system during a sample load operation. The tray drive is also used to move the sample tray along the path during a temperature averaging period when no loading occurs. Differences in sample temperatures due to variations in the air temperature at different locations inside the sample compartment are reduced, leading to more accurate and repeatable chromatographic measurement results.Type: ApplicationFiled: January 11, 2011Publication date: January 24, 2013Applicant: WATERS TECHNOLOGIES CORPORATIONInventors: Joshua A. Shreve, James E. Usowicz, Miguel Soares
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Publication number: 20120304745Abstract: A liquid chromatography system includes an autosampler that prepares a sample for introduction to a solvent stream and a solvent delivery system that delivers a solvent stream to the autosampler. Delivery of the solvent stream occurs in parallel with the autosampler's pre-injection operations. The autosampler starts pre-injection operations to make the sample ready for injection into the mixture stream, and the solvent delivery system starts delivery of a solvent stream to the autosampler. The start of the solvent stream delivery is coordinated with the start of the pre-injection operations such that the solvent stream arrives at the autosampler approximately coincident with when the autosampler completes the pre-injection operations, making the sample ready for injection.Type: ApplicationFiled: November 11, 2010Publication date: December 6, 2012Applicant: WATERS TECHNOLOGIES CORPORATIONInventors: John Heden, John Lamoureux, Miguel Soares, Guo-Zhong Li
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COORDINATING INJECTOR-VALVE SWITCHING WITH PUMP-STROKE TIMING TO MITIGATE EFFECTS OF PRESSURE PULSES
Publication number: 20120303167Abstract: A liquid chromatography system includes an autosampler with an injector valve by which a sample at low pressure within a sample loop is introduced into a high-pressure solvent mixture stream. A solvent delivery system includes a pump in fluidic communication with the injector valve of the autosampler to deliver the solvent mixture stream thereto. The solvent delivery system further comprises a processor that calculates a number of strokes of the pump needed to deliver the solvent mixture stream to the injector valve of the autosampler. The processor counts strokes of the pump during delivery of the solvent mixture stream. In response to a stroke count equaling the calculated number of strokes, the processor signals the autosampler to switch the injector valve to introduce the sample to the solvent mixture stream during a pump transfer period within which the pump performs pressure control to compensate for a drop in pressure.Type: ApplicationFiled: November 11, 2010Publication date: November 29, 2012Applicant: WATERS TECHNOLOGIES CORPORATIONInventors: John Heden, John Lamoureux, Miguel Soares, Guo-Zhong Li -
Patent number: 8312762Abstract: Embodiments of the present invention are directed to methods and apparatus for placing a sample in a chromatographic system. The device and method feature placing samples held in a sample loop to pressurization prior to placing such sample loop in communication with high pressure conduits.Type: GrantFiled: March 16, 2007Date of Patent: November 20, 2012Assignee: Waters Technologies CorporationInventors: Keith Fadgen, James E. Usowicz, Miguel Soares
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Patent number: 8160751Abstract: Systems, devices, and methods to mitigate the pressure disturbance associated with the injection of low-pressure analyte samples into a high-pressure HPLC fluid stream, to enhance chromatographic performance related to retention time and reproducibility. The preferred embodiment coordinates the injection run with active pressure control of a binary solvent delivery system to virtually eliminate the customary pressure drop when the low-pressure loop is brought on line. An additional benefit that enhances reproducibility is accomplished by forcing a consistent timing relationship between the injection run, the mechanical position of the delivery pump pistons, and the start and subsequent gradient delivery.Type: GrantFiled: February 25, 2011Date of Patent: April 17, 2012Assignee: Waters Technologies CorporationInventors: Stanley P. Pensak, Jr., John Heden, Steven J. Ciavarini, John Lamoureux, Miguel Soares
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Publication number: 20110202188Abstract: Systems, devices, and methods to mitigate the pressure disturbance associated with the injection of low-pressure analyte samples into a high-pressure HPLC fluid stream, to enhance chromatographic performance related to retention time and reproducibility. The preferred embodiment coordinates the injection run with active pressure control of a binary solvent delivery system to virtually eliminate the customary pressure drop when the low-pressure loop is brought on line. An additional benefit that enhances reproducibility is accomplished by forcing a consistent timing relationship between the injection run, the mechanical position of the delivery pump pistons, and the start and subsequent gradient delivery.Type: ApplicationFiled: February 25, 2011Publication date: August 18, 2011Applicant: Waters Technologies CorporationInventors: Stanley P. Pensak, JR., John Heden, Steven J. Ciavarini, John Lamoureux, Miguel Soares
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Patent number: 7917250Abstract: Systems, devices, and methods to mitigate the pressure disturbance associated with the injection of low-pressure analyte samples into a high-pressure HPLC fluid stream to enhance chromatographic performance related to retention time and reproducibility. The injection event is coordinated with active pressure control of a binary solvent delivery system to virtually eliminate the customary pressure drop when the low-pressure loop is brought on line. Consistent timing with the injection event of the mechanical position of the delivery pump pistons, and the start and subsequent gradient delivery generates reproducible results.Type: GrantFiled: August 19, 2005Date of Patent: March 29, 2011Assignee: Waters Technologies CorporationInventors: Stanley P. Pensak, Jr., John Heden, Steven J. Ciavarini, John Lamoureux, Miguel Soares
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Publication number: 20100043539Abstract: Embodiments of the present invention are directed to methods and apparatus for placing a sample in a chromatographic system. The device and method feature placing samples held in a sample loop to pressurization prior to placing such sample loop in communication with high pressure conduits.Type: ApplicationFiled: March 16, 2007Publication date: February 25, 2010Applicant: WATERS INVESTMENTS LIMITEDInventors: Keith Fadgen, James E. Usowicz, Miguel Soares
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Patent number: 7596988Abstract: A device (100) for detecting a condition in a fluid system (14) and initiating a response based on the condition. The device consists of a sensor (12) that responds to a first and second condition of the fluid (13) in the system and a control means (10) that receives the responses and generates command signals in based on the received response. In a liquid chromatography system, the device is used to determine the volume of components of the fluid system. In addition, the device allow leaks to be detected and permits the fluid in the system to be transported at a optimum speed. The device is well implemented utilizing to a light emitter and light receptor that are sensitive to the fluid in either a gaseous or liquid state.Type: GrantFiled: March 2, 2005Date of Patent: October 6, 2009Assignee: Waters Technologies CorporationInventors: James E. Usowicz, Peyton C. Beals, Russell Keene, Richard Kent, Miguel Soares, John Heden
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Publication number: 20090062966Abstract: Systems, devices, and methods to mitigate the pressure disturbance associated with the injection of low-pressure analyte samples into a high-pressure HPLC fluid stream (52), to enhance chromatographic performance related to retention time and reproducibility. The preferred embodiment coordinates the injection run with active pressure control of a binary solvent delivery system (30) to virtually eliminate the customary pressure drop when the low-pressure loop is brought on line. An additional benefit that enhances reproducibility is accomplished by forcing a consistent timing relationship between the injection run, the mechanical position of the delivery pump pistons, and the start and subsequent gradient delivery.Type: ApplicationFiled: August 19, 2005Publication date: March 5, 2009Applicant: WATERS INVESTMENTS LIMITEDInventors: Stanley P. Pensak, JR., John Heden, Steven J. Ciavarini, John Lamoureux, Miguel Soares
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Publication number: 20070287192Abstract: A device (100) for detecting a condition in a fluid system (14) and initiating a response based on the condition. The device consists of a sensor (12) that responds to a first and second condition of the fluid (13) in the system and a control means (10) that receives the responses and generates command signals in based on the received response. In a liquid chromatography system, the device is used to determine the volume of components of the fluid system. In addition, the device allow leaks to be detected and permits the fluid in the system to be transported at a optimum speed. The device is well implemented utilizing to a light emitter and light receptor that are sensitive to the fluid in either a gaseous or liquid state.Type: ApplicationFiled: March 2, 2005Publication date: December 13, 2007Applicant: Waters Investments LimitedInventors: James Usowicz, Peyton Beals, Russell Keene, Richard Kent, Miguel Soares, John Heden
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Publication number: 20070202083Abstract: The present invention features methods for transplanting organs, tissues and individual cells. Also featured are methods for maintaining cells in vitro and for enhancing survival and/or function of cells following transplantation. The methods include the administration of carbon monoxide in an amount sufficient to enhance cell survival and/or function.Type: ApplicationFiled: April 10, 2006Publication date: August 30, 2007Inventors: Fritz Bach, Leo Otterbein, Miguel Soares, Edda Tobiasch, Jeanne Gose