Patents by Inventor Miguel Suastegui

Miguel Suastegui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11332751
    Abstract: The present disclosure includes methods and components for production of valuable industrial compounds in yeast. In an embodiment, the present invention provides a nucleic acid construct with increased stability for gene expression or gene editing comprising: a nucleic acid sequence encoding one or more of SEQ ID NO: 1-8 (CENs 1-8); and one or more regulatory elements functional in a yeast cell. In an embodiment of the present invention the nucleic acid constructs are vectors, preferably episomal vectors. High expression promoters, as well as methods for increasing production of compounds such as aromatics are disclosed.
    Type: Grant
    Filed: July 28, 2020
    Date of Patent: May 17, 2022
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Zengyi Shao, Mingfeng Cao, Miguel Suastegui, Meirong Gao
  • Publication number: 20210270831
    Abstract: Modular biohybrid systems, some of which suitable for photochemical biosynthesis, are described. These systems are characterized by functionalized photocatalytic nanoparticles that are independently prepared, then assembled and attached to the modified surface of a cell, thereby enabling the cell to absorb light energy and convert it into chemical energy, for example in the form of a redox cofactor. The generated chemical energy then serves as fuel for production pathways of metabolites useful for the manufacturing of fuels, nutraceuticals, pharmaceuticals and cosmetics.
    Type: Application
    Filed: June 25, 2019
    Publication date: September 2, 2021
    Inventors: Junling Guo, Miguel Suastegui, Neel Saitish Joshi
  • Publication number: 20210040490
    Abstract: The present disclosure includes methods and components for production of valuable industrial compounds in yeast. In an embodiment, the present invention provides a nucleic acid construct with increased stability for gene expression or gene editing comprising: a nucleic acid sequence encoding one or more of SEQ ID NO: 1-8 (CENs 1-8); and one or more regulatory elements functional in a yeast cell. In an embodiment of the present invention the nucleic acid constructs are vectors, preferably episomal vectors. High expression promoters, as well as methods for increasing production of compounds such as aromatics are disclosed.
    Type: Application
    Filed: July 28, 2020
    Publication date: February 11, 2021
    Inventors: Zengyi Shao, Mingfeng Cao, Miguel Suastegui, Meirong Gao
  • Patent number: 10787672
    Abstract: The present disclosure includes methods and components for production of valuable industrial compounds in yeast. In an embodiment, the present invention provides a nucleic acid construct with increased stability for gene expression or gene editing comprising: a nucleic acid sequence encoding one or more of SEQ ID NO: 1-8 (CENs 1-8); and one or more regulatory elements functional in a yeast cell. In an embodiment of the present invention the nucleic acid constructs are vectors, preferably episomal vectors. High expression promoters, as well as methods for increasing production of compounds such as aromatics are disclosed.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: September 29, 2020
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Zengyi Shao, Mingfeng Cao, Miguel Suastegui, Meirong Gao
  • Publication number: 20190002892
    Abstract: The present disclosure includes methods and components for production of valuable industrial compounds in yeast. In an embodiment, the present invention provides a nucleic acid construct with increased stability for gene expression or gene editing comprising: a nucleic acid sequence encoding one or more of SEQ ID NO: 1-8 (CENs 1-8); and one or more regulatory elements functional in a yeast cell. In an embodiment of the present invention the nucleic acid constructs are vectors, preferably episomal vectors. High expression promoters, as well as methods for increasing production of compounds such as aromatics are disclosed.
    Type: Application
    Filed: June 27, 2018
    Publication date: January 3, 2019
    Inventors: Zengyi Shao, Mingfeng Cao, Miguel Suastegui, Meirong Gao