Patents by Inventor Miha Vrbinc

Miha Vrbinc has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOLID PHARMACEUTICAL COMPOSITION COMPRISING DONEPEZIL HYDROCHLORIDE
    Publication number: 20120283291
    Abstract: The invention relates to a solid pharmaceutical composition comprising donepezil hydrochloride hydrate and a process for its preparation. In particular it relates to a composition and a process wherein the donepezil hydrochloride retains its polymorphic form and is therefore highly stable against conversion into other polymorphic forms.
    Type: Application
    Filed: January 10, 2012
    Publication date: November 8, 2012
    Applicant: KRKA, TOVARNA ZDRAVIL D.D., NOVO MESTO
    Inventors: Miha Vrbinc, Berta Kotar-Jordan, Rok Zupet, Matej J. Smrkolj
  • Process for the preparation of olmesartan medoxomil
    Patent number: 7943779
    Abstract: The present invention relates to an improved process for the manufacture of olmesartan and pharmaceutically acceptable salts and esters thereof as an active ingredient of a medicament for the treatment of hypertension and related diseases and conditions.
    Type: Grant
    Filed: July 27, 2006
    Date of Patent: May 17, 2011
    Assignee: KRKA
    Inventors: Silvo Zupancic, Anica Pecavar, Miha Vrbinc, Renata Osolnik
  • SOLID PHARMACEUTICAL COMPOSITION COMPRISING IRBESARTAN
    Publication number: 20110045097
    Abstract: The present invention concerns preferably surfactant-free solid pharmaceutical formulations comprising, as an active ingredient, at least one of irbesartan and pharmaceutically acceptable salts thereof, and at least one disintegrant. Preferably, the active ingredient comprises irbesartan hydrochloride. Also, the present invention is directed to a process for the manufacture of such formulations, including a wet granulation process (A) and a direct granulation process (B).
    Type: Application
    Filed: January 5, 2007
    Publication date: February 24, 2011
    Applicant: KRKA, d.d. Novo mesto
    Inventors: Miha Vrbinc, Renata Jakse, Franci Bevec, Silvo Zupancic
  • Solid pharmaceutical composition comprising donepezil hydrochloride
    Publication number: 20100317694
    Abstract: The invention relates to a solid pharmaceutical composition comprising donepezil hydrochloride hydrate and a process for its preparation. In particular it relates to a composition and a process wherein the donepezil hydrochloride retains its polymorphic form and is therefore highly stable against conversion into other polymorphic forms.
    Type: Application
    Filed: January 20, 2010
    Publication date: December 16, 2010
    Applicant: KRKA, TOVARNA ZDRAVIL, D.D. , NOVO MESTO
    Inventors: Miha Vrbinc, Berta Kotar-Jordan, Rok Zupet, Matej Smrkolj
  • Solid Pharmaceutical Composition Comprising Donepezil Hydrochloride
    Publication number: 20090130205
    Abstract: The invention relates to a solid pharmaceutical composition comprising donepezil hydrochloride hydrate and a process for its preparation. In particular it relates to a composition and a process wherein the donepezil hydrochloride retains its polymorphic form and is therefore highly stable against conversion into other polymorphic forms.
    Type: Application
    Filed: October 19, 2005
    Publication date: May 21, 2009
    Applicant: KRKA, TOVARNA ZDRAVIL D.D., NOVO MESTO
    Inventors: Miha Vrbinc, Berta Kotar-Jordan, Rok Zupet, Matej Smrkolj
  • PROCESS FOR THE PREPARATION OF OLMESARTAN MEDOXOMIL
    Publication number: 20090131680
    Abstract: The present invention relates to an improved process for the manufacture of olmesartan and pharmaceutically acceptable salts and esters thereof as an active ingredient of a medicament for the treatment of hypertension and related diseases and conditions.
    Type: Application
    Filed: July 27, 2006
    Publication date: May 21, 2009
    Applicant: KRKA
    Inventors: Silvo Zupancic, Anica Pecavar, Miha Vrbinc, Renata Osolnik
  • Solid Pharmaceutical Composition Comprising Valsartan
    Publication number: 20080102120
    Abstract: This invention relates to a solid pharmaceutical composition containing valsartan particles characterized in that the D50 of said valsartan particles is 150 ?m or below and that the valsartan particles have a maximum diameter of no more than 1100 ?m, as determined by electron microscopy.
    Type: Application
    Filed: December 23, 2005
    Publication date: May 1, 2008
    Inventors: Miha Vrbinc, Janika Slanc Vovk, Marija Rangus, Silvo Zupancic, Franci Bevec, Lidija Cernosa
  • Solid Pharmaceutical Composition Comprising Donepezil Hydrochloride
    Publication number: 20080063705
    Abstract: The invention relates to a solid pharmaceutical composition comprising donepezil hydrochloride hydrate and a process for its preparation. In particular it relates to a composition and a process wherein the donepezil hydrochloride retains its polymorphic form and is therefore highly stable against conversion into other polymorphic forms.
    Type: Application
    Filed: October 19, 2005
    Publication date: March 13, 2008
    Applicant: KRKA, TOVARNA ZDRAVIL D.D., NOVO MESTO
    Inventors: Miha Vrbinc, Berta Kotar-Jordan, Rok Zupet, Matej Smrkolj