Patents by Inventor Mihail Yurievich Beburov

Mihail Yurievich Beburov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing web protein, a fused protein, recombinant DNA, an expression vector, a host cell and strain-producers
    Patent number: 9475852
    Abstract: The invention relates to the field of biotechnology and provides a method for producing recombinant proteins from the orb-weaving spider silk in yeast cells. This involves the construction of an expression vector which comprises a DNA sequence encoding a recombinant protein of the orb-weaving spider silk fused with a sequence encoding an ubiquitin-like protein occupying an N-terminal position with respect to the spider silk recombinant protein within the fused protein. The expression of a hybrid gene makes it possible to increase tens of times the production of recombinant spider silk protein, wherein the recombinant protein accumulates in the yeast cells in a water-insoluble fraction in the form of a processed protein free of a hybrid component.
    Type: Grant
    Filed: December 13, 2010
    Date of Patent: October 25, 2016
    Inventors: Vladimir Grigorievich Bogush, Mihail Yurievich Beburov, Vladimir Georgievich Debabov, Dmitriy Georgievich Kozlov, Irek Ilyasovich Gubaydullin, Lyubov Ivanovna Davydova, Igor Arsenievich Zalunin, Konstantin Vasilievich Sidoruk, Sergey Eduardovich Cheperegin
  • METHOD FOR PRODUCING WEB PROTEIN, A FUSED PROTEIN, RECOMBINANT DNA, AN EXPRESSION VECTOR, A HOST CELL AND STRAIN-PRODUCERS
    Publication number: 20140094589
    Abstract: The invention relates to the field of biotechnology and provides a method for producing recombinant proteins from the orb-weaving spider silk in yeast cells. This involves the construction of an expression vector which comprises a DNA sequence encoding a recombinant protein of the orb-weaving spider silk fused with a sequence encoding an ubiquitin-like protein occupying an N-terminal position with respect to the spider silk recombinant protein within the fused protein. The expression of a hybrid gene makes it possible to increase tens of times the production of recombinant spider silk protein, wherein the recombinant protein accumulates in the yeast cells in a water-insoluble fraction in the form of a processed protein free of a hybrid component.
    Type: Application
    Filed: December 13, 2010
    Publication date: April 3, 2014
    Inventors: Vladimir Grigorievich Bogush, Mihail Yurievich Beburov, Vladimir Georgievich Debabov, Dmitriy Georgievich Kozlov, Irek Ilyasovich Gubaydullin, Lyubov Ivanovna Davydova, Igor Arsenievich Zalunin, Konstantin Vasilievich Sidoruk, Sergey Eduardovich Cheperegin