Patents by Inventor Mihaly Nogradi

Mihaly Nogradi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4599327
    Abstract: 2,6-di-O-methyl-beta-cyclodextrin complexes of compounds of the formula (1a) ##STR1## wherein R.sup.2' stands for C.sub.1 to C.sub.12 alkyl or a group of the formula ##STR2## in which R.sup.11 is C.sub.1 to C.sub.4 alkyl;R.sup.12 is hydrogen or C.sub.1 to C.sub.4 alkyl;n is 0 or 1;p is 1 to 4;r is 1 to 4; andR.sup.3' and R.sup.4' are each C.sub.1 to C.sub.4 alkyl, or pharmaceutically salts thereof are disclosed, having analgesic activity.
    Type: Grant
    Filed: December 2, 1983
    Date of Patent: July 8, 1986
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara RT
    Inventors: Mihaly Nogradi, Dezso Korbonits, Agnes Gottsegen, Sandor Antus, Zsuzsa Furst, Jozsef Knoll, Jozsef Szejtli, Agnes Stadler, Gabor Kovacs, Katalin Marmarosi
  • Patent number: 4391821
    Abstract: The present invention relates to novel 7-substituted benzopyranes of formula (I), whereinR.sub.1 and R.sub.2 are hydrogen, alkyl of from 1 to 6 carbon atoms, hydroxyalkyl, alkenyl, cycloalkyl, phenylalkyl, dimethoxy-phenylalkyl, or R.sub.1 and R.sub.2 together with the joining nitrogen atom may represent a 5-7-membered heterocyclic ring,R.sub.3 is hydrogen, alkyl of from 1 to 4 carbon atoms or phenyl,R.sub.4 is hydrogen,R.sub.5 is hydrogen or phenyl, orR.sub.4 and R.sub.5 together may represent a bonding electron pair between the second and the third carbon atoms of the benzopyrane ring,R.sub.6 and R.sub.7 are hydrogen or they may represent an oxygen atom together,n is 1 or 2,with the proviso, that the pyrane ring may bear only one alkyl or phenyl substituent, and preparation process thereof.The novel compounds have valuable therapeutical effects, mainly in cardiotherapy.
    Type: Grant
    Filed: July 17, 1981
    Date of Patent: July 5, 1983
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
    Inventors: Dezso Korbonits, Mihaly Nogradi, Borbala Vermes nee Szluha, Janos Strelisky, Andras Wolfner, Gergely Heja, Gabor Kovacz, Jozsef Szegi, Sandor Virag
  • Patent number: 4166862
    Abstract: An animal feed containing 0.00002 to 0.1% by weight of:2-methyl-7-methoxy-4'-nitroisoflavone,7-[hydroxyethoxy]-2-methylisoflavone,7-carbethoxy-2-methylisoflavone,7-ethoxyisoflavone,7-n-benzyloxy-2-methylisoflavone,7-p-nitrobenzyloxyisoflavone,7-p-nitrobenzyloxy-2-methylisoflavone,7-p-chlorobenzyloxyisoflavone,7-cetyloxy-2-methylisoflavone,7-(2-octyloxy)-isoflavone,7-benzyloxy-3',4'-dimethoxyisoflavone, and7-hexadecyloxyisoflavoneAs a weight-gain promoting anabolic ingredient.
    Type: Grant
    Filed: May 16, 1974
    Date of Patent: September 4, 1979
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
    Inventors: Laszlo Feuer, Mihaly Nogradi, Agnes Gettsegen, Borbala Vermes, Janos Strelisky, Andras Wolfner, Lorant Farkas, Sandor Antus, Maria K. Toth
  • Patent number: 4163746
    Abstract: Nonestrogenic 5-methyl-alkoxy-isoflavone, namely, 5-methyl-7-methoxy-isoflavone, 5-methyl-7-ethoxy-isoflavone, 5-methyl-7-isopropoxy-isoflavone, and 5-methyl-7-(2-hydroxy-ethoxy)-isoflavone are useful as weight-gain promoters in feeds from which the 7-methoxy and 7-ethoxy isoflavones have been excluded because of estrogenic effects. They are more effective than 7-isopropoxy-isoflavone as well.
    Type: Grant
    Filed: October 26, 1977
    Date of Patent: August 7, 1979
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
    Inventors: Laszlo Feuer, Lorand Farkas, Mihaly Nogradi, Borbala Vermes, Agnes Gottsegen, Andras Wolfner
  • Patent number: 4092346
    Abstract: Compounds of the formula (1), or their salts, ##STR1## are prepared as follows: (A) A COMPOUND OF THE FORMULA (II) ##STR2## is reduced; or (B) A COMPOUND OF THE FORMULA (III) ##STR3## is reacted, e.g. after protecting the phenolic hydroxy group attached to position 3 of the ring, with a compound of the formula (IV), ##STR4## or (C) GROUP R.sup.1 of a compound of the formula (V) ##STR5## is removed in an acidic medium, AND, IF DESIRED, THE COMPOUND OF THE FORMULA (I) is converted into salt, or a salt of a compound of the formula (I) is converted into the free acid or another salt thereof.The compounds of the formula (I) and their salts are valuable artificial sweetening agents.In the above formulae"alkyl" is a C.sub.1-4 alkyl group,R is hydrogen or a protecting group capable of splitting off upon hydrogenolysis, preferably benzyl or benzyloxycarbonyl,M+ is a proton or another cation,X is a group of the general formula O.sup.- M.sup.+,Y is halogen, orX and Y together represent an oxygen atom, andR.sup.
    Type: Grant
    Filed: December 1, 1976
    Date of Patent: May 30, 1978
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
    Inventors: Lorand Farkas, Mihaly Nogradi, Todor Pfliegel, Sandor Antus, Agnes Gottsegen
  • Patent number: 3956375
    Abstract: A sweetening agent in the form of a 1,3-diphenyl-propanone-1 derivative of the formula ##SPC1##Wherein R is hydrogen, hydroxyl, alkoxy or carboxyl-substituted, sulphonyl-substituted, phosphonyl-substituted, dialkylamino-substituted, trialkyl ammonium-substituted alkoxy; R.sup.1 is hydrogen or a hydrophylic group but both R and R.sup.1 are not both hydrogen; R.sup.2 and R.sup.3 are hydroxyl or alkoxy.
    Type: Grant
    Filed: December 4, 1972
    Date of Patent: May 11, 1976
    Assignee: Chinoin Gyogyszer-es Vegyeszeti Termekek Gyara RT
    Inventors: Lorant Farkas, Mihaly Nogradi, Agnes Gottsegen, Sandor Antus
  • Patent number: 3949085
    Abstract: A method of anabolic treatment in humans comprises administering a compound of the following formula: ##SPC1##Wherein R is halosubstituted, nitrosubstituted, or unsubstituted benzyl, R.sup.2 is hydrogen, methyl or carboxy, and R.sup.3 and R.sup.4 are hydrogen, methoxy or nitro. Pharmaceutical compositions are also disclosed.
    Type: Grant
    Filed: August 15, 1974
    Date of Patent: April 6, 1976
    Assignee: Chinoin Gyogyszer-es Vegyeszeti Termakek Gyara RT
    Inventors: Laszlo Feuer, Mihaly Nogradi, Agnes Gottsegen, Borbala Vermes, Janos Streliszky, Andreas Wolfner, Lorant Farkas, Sandor Antus, Maria Kovaks