Patents by Inventor Miharu Igarashi

Miharu Igarashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of Using 4-Amino-N-[4-(Methoxymethyl)Phenyl]-7-(1-Methylcyclopropyl)-6-(3-Morpholinoprop-1-YN-1-YL)-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carboxamide for the Treatment of Tumors
    Publication number: 20240000791
    Abstract: The present invention relates to compositions and methods for treating patients with cancer having a RET gene abnormality comprising administering HM06/TAS0953, for example patients with non-small cell lung cancer (NSCLC), and that may also have brain and/or leptomeningeal metastases, or another solid tumor; where the patient is administered an effective amount of HM06/TAS0953, where the HM06/TAS0953 can be formulated in a composition and administered orally in a single or multiple doses; and where the patients may have previously received and/or have developed resistance to another RET-selective or multi-kinase inhibitor.
    Type: Application
    Filed: November 18, 2021
    Publication date: January 4, 2024
    Applicants: Helsinn Healthcare SA, Taiho Pharmaceutical Co., Ltd.
    Inventors: Emanuela Lovati, Ruben Giorgino, Simona Doria, Claudio Giuliano, Annalisa Bonifacio, Miharu Igarashi, Isao Miyazaki, Masanori Kato, Alberto Bernareggi