Patents by Inventor Miho Furue

Miho Furue has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11222423
    Abstract: An evaluation device includes a state determination unit which is configured to determine a state of cells which are an observation target under non-standard conditions on the basis of information acquired from an image of cells under standard conditions.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: January 11, 2022
    Assignees: Nikon Corporation, National Institutes Of Biomedical Innovation, Health And Nutrition
    Inventors: Hiroaki Kii, Yasujiro Kiyota, Takayuki Uozumi, Miho Furue, Mika Suga
  • Publication number: 20170009203
    Abstract: Disclosed are: a gene transduction method for use in the induction of the differentiation of stem cells such as ES cells or iPS cells into hepatocytes effectively; stem cells into each of which a gene useful for the induction of the differentiation into hepatocytes is introduced; and hepatocytes produced from stem cells each having the gene introduced therein. A specific gene can be introduced into stem cells such as ES cells or iPS cells using an adenovirus vector. The effective induction of the differentiation into hepatocytes can be achieved by introducing the gene. Specifically, the effective induction of the differentiation of stem cells such as ES cells or iPS cells into hepatocytes can be achieved by introducing at least one gene selected from HEX gene, HNF4A gene, HNF6 gene and SOX17 gene into the stem cells.
    Type: Application
    Filed: September 16, 2016
    Publication date: January 12, 2017
    Applicant: Japan Health Sciences Foundation
    Inventors: Hiroyuki Mizuguchi, Kenji Kawabata, Mitsuru Inamura, Miho Furue
  • Publication number: 20130309768
    Abstract: An aim of the present invention is to provide a method for culturing a human pluripotent stem cell while maintaining an undifferentiated state, more efficiently than conventional methods, and a kit therefor. The pluripotency of a stem cell was found to be maintained at a high rate, regardless of experimenter's proficiency in culturing techniques, by (a) culturing a human pluripotent stem cell in a first medium which a medium for pluripotent stem cell comprising activin; (b) replacing the first medium with a second medium which is a medium for pluripotent stem cell comprising no activin, and culturing the human pluripotent stem cell, (c) subculturing the human pluripotent stem cell into the first medium, and then repeating the above (b) and (c) sequentially.
    Type: Application
    Filed: August 24, 2011
    Publication date: November 21, 2013
    Applicant: NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION
    Inventors: Miho Furue, Masaki Kinehara
  • Publication number: 20120231490
    Abstract: Disclosed are: a gene transduction method for use in the induction of the differentiation of stem cells such as ES cells or iPS cells into hepatocytes effectively; stem cells into each of which a gene useful for the induction of the differentiation into hepatocytes is introduced; and hepatocytes produced from stem cells each having the gene introduced therein. A specific gene can be introduced into stem cells such as ES cells or iPS cells using an adenovirus vector. The effective induction of the differentiation into hepatocytes can be achieved by introducing the gene. Specifically, the effective induction of the differentiation of stem cells such as ES cells or iPS cells into hepatocytes can be achieved by introducing at least one gene selected from HEX gene, HNF4A gene, HNF6 gene and SOX17 gene into the stem cells.
    Type: Application
    Filed: October 22, 2010
    Publication date: September 13, 2012
    Applicant: JAPAN HEALTH SCIENCES FOUNDATION
    Inventors: Hiroyuki Mizuguchi, Kenji Kawabata, Mitsuru Inamura, Miho Furue
  • Patent number: 7923245
    Abstract: The present invention discloses a medium for a serum-free medium capable of culturing ES cells for a long period while maintaining their undifferentiated state without using feeder cells, and a basal medium for producing the medium thus described. The basal medium of the present invention is characterized by that it has composition shown by Table I. Further, the present invention discloses a medium for ES cells produced with the basal medium.
    Type: Grant
    Filed: December 27, 2004
    Date of Patent: April 12, 2011
    Inventors: Miho Furue, Tetsuji Okamoto, Makoto Asashima
  • Publication number: 20080050817
    Abstract: The present invention discloses a medium for a serum-free medium capable of culturing ES cells for a long period while maintaining their undifferentiated state without using feeder cells, and a basal medium for producing the medium thus described. The basal medium of the present invention is characterized by that it has composition shown by Table I. Further, the present invention discloses a medium for ES cells produced with the basal medium.
    Type: Application
    Filed: December 27, 2004
    Publication date: February 28, 2008
    Inventors: Miho Furue, Tetsuji Okamoto, Makoto Asashima