Abstract: A medical device having a function of promoting fusion between living body organs, which includes a sheet-like main body portion configured to promote fusion of anastomosis portions, a cylindrical portion that is disposed on a center portion side in a plane direction of the main body portion with respect to an outer peripheral portion in the plane direction of the main body portion, protrudes in a first direction intersecting the plane direction of the main body portion, and has a lumen, and a connection portion that connects the main body portion and the cylindrical portion, and the medical device 100 is configured so that a relationship among hardness of the cylindrical portion, hardness of the connection portion, and hardness of the main body portion satisfies the following expression (1): hardness of cylindrical portion >hardness of connection portion >hardness of main body portion (1).

Abstract: A medical member having flexibility and strength suitable for application to anastomotic portions, and having effectively improved breaking processability. The medical member includes a mesh-like main body that promotes adhesion of the anastomotic portions, in which the main body includes a breakable portion having a relationship between a breaking strength and a compression elongation percentage, represented by the following formulas (1) to (4): Y ? 244734 ? ( X - Z ) - 1.665 ( 1 ) 0 ? Z < 408.216 ( 2 ) X - Z > 0 ( 3 ) 39 ? X .

Abstract: To reduce the risk of a ruptured suture after a surgery or the like, a medical apparatus includes a biodegradable sheet in which a plurality of through-holes are formed, a value of a ratio (D/P) of a hole diameter D to a pitch P of the through-hole is in a range of 0.25 or more and less than 40. Such a medical apparatus is useful as an adhesion promoting device for promoting adhesion of biological tissue.

Abstract: A sheet-shaped cell culture for covering a cut surface of a pancreas, the cut surface of the pancreas includes cut surfaces of a pancreatic parenchyma and a pancreatic duct, and is connected to an intestinal wall of a small intestine in a liquid-tight manner via the sheet-shaped cell culture. A method for preventing or treating pancreatic fistula includes a step of covering, using a sheet-shaped cell culture, a cut surface of a pancreas that includes cut surfaces of a pancreatic parenchyma and a pancreatic duct, and a step of connecting the cut surface of the pancreas to an intestinal wall of a small intestine in a liquid-tight manner via the sheet-shaped cell culture.

Abstract: A medical device is disclosed, which capable of reducing risk factors of an anastomotic leakage after a surgical operation is performed. The adhesion promoting device includes an adhesion promotion sheet provided with an adhesion promotion portion that promotes adhesion of biological tissues, and a holding portion that allows the adhesion promotion sheet to be hooked and held on a biological organ to be joined.

Abstract: A medical device is disclosed capable of reducing risk factors of an anastomotic leakage after a surgical operation is performed. The medical device includes an adhesion promotion sheet configured to include an adhesion promotion portion promoting adhesion of biological tissues and a frame portion provided outside the adhesion promotion portion in a plane direction and a pulling unit connected to the adhesion promotion sheet and configured to deform a second region so as to cover at least a portion of an outer peripheral surface of a biological organ to be joined with a pulling operation.

Abstract: An adhesion promotion device is disclosed, which is capable of reducing risk factors of an anastomotic leakage after surgery. The adhesion promotion device includes a sheet-shaped first region disposed between one joint target site and the other joint target site of biological organs to promote adhesion of a biological tissue, a second region provided inward of the first region and separated from the first region in a direction intersecting with a surface direction of the first region, and an interlock portion that interlocks the first region and the second region with each other.

Abstract: A treatment method and a treatment system capable of effectively irradiating an antibody-photosensitive substance bound to a tumor cell with a near-infrared ray. The treatment method includes: intravenously administering the antibody-photosensitive substance; inserting a guide wire and a catheter into a main artery of an organ having the tumor cell; removing the guide wire; inserting an optical fiber into the catheter and advancing the optical fiber to a target position while checking a position of the optical fiber with an orientation marker disposed on the optical fiber; and irradiating the antibody-photosensitive substance bound to a tumor cell membrane with the near-infrared ray from the optical fiber while reducing an influence of blood in the artery on the near-infrared ray after 12 hours to 36 hours from intravenous administration.

Abstract: A treatment method and a treatment system capable of effectively irradiating an antibody-photosensitive substance bound to a tumor cell with a near-infrared ray. The treatment method for irradiating the antibody-photosensitive substance bound to the tumor cell membrane in the tumor cell with the near-infrared ray includes: intravenously administering the antibody-photosensitive substance; percutaneously puncturing a tumor or a vicinity of the tumor with a hollow outer needle, while percutaneously acquiring and checking an ultrasound image; making an inner needle having a plurality of sharp inner needle tips protrude from the outer needle, and puncturing the tumor or the vicinity of the tumor with the inner needle tips; and irradiating the antibody-photosensitive substance bound to the tumor cell membrane with the near-infrared ray from an optical fiber inserted into the inner needle after 12 hours to 36 hours from the intravenous administration.

Abstract: Provided is a treatment method that reduces risk factors contributing to anastomotic leakage by using a medical device. The treatment method includes placing a medical device including a sheet-like main body portion for promoting adhesion between biological tissues between one joint target site and another joint target site of a biological organ to be joined, and joining the one joint target site and the other joint target site to each other in a state where at least a portion of the main body portion is interposed between the one joint target site and the other joint target site.

Abstract: An adhesion promotion device configured to reduce risk factors of an anastomotic leakage after a surgical operation is performed includes a main body portion and a reinforcement portion. The main body portion is formed of a biodegradable sheet that promotes adhesion of biological tissues and includes a plurality of through-holes. The reinforcement portion is disposed at a portion of the main body portion and reinforces the main body portion.

Abstract: 4 There are provided an adhesion promotion device and a medical device which are capable of effectively reducing risk factors of an anastomotic leakage. The adhesion promotion device has a main body portion formed of a biodegradable sheet having a plurality of through-holes and promoting adhesion of biological tissues, and an assistance unit provided in the main body portion and assisting the main body portion to hold a biological organ serving as an object to be joined.

Abstract: To reduce the risk of a ruptured suture after a surgery or the like, a medical apparatus includes a biodegradable sheet in which a plurality of through-holes are formed, a value of a ratio (D/P) of a hole diameter D to a pitch P of the through-hole is in a range of 0.25 or more and less than 40. Such a medical apparatus is useful as an adhesion promoting device for promoting adhesion of biological tissue.

Abstract: Provided is a treatment method that reduces risk factors contributing to anastomotic leakage by using a medical device. The treatment method includes placing a medical device including a sheet-like main body portion for promoting adhesion between biological tissues between one joint target site and another joint target site of a biological organ to be joined, and joining the one joint target site and the other joint target site to each other in a state where at least a portion of the main body portion is interposed between the one joint target site and the other joint target site.

Abstract: A fixing tool is disclosed, which can help reduce a possibility that heat may be transferred to a user when a state is changed in a material of a member for fixing a predetermined site of a human body. The fixing tool has a deformation portion that is configured to be deformable, that at least partially covers an outer periphery of any site of a limb, a trunk, a neck, and a head, and that is deformed to align with the site through the deformation, and a heat insulating material that is disposed in a portion corresponding to at least the site on an outside surface of the deformation portion.

Abstract: There is provided an applicator for ejecting together with a gas a mixed liquid obtained by mixing a first liquid and a second liquid which are different from each other in composition. The applicator includes a first liquid flow path through which the first liquid flows; a second liquid flow path through which the second liquid flows; a gas flow path through which the gas flows; a confluence section in which the first liquid and the second liquid merge; and a backflow preventing section that prevents backflow of the first liquid and prevents backflow of the second liquid.

Abstract: There is provided an applicator including: a first liquid flow path through which a first liquid containing fibrinogen passes; a second liquid flow path through which a second liquid containing thrombin passes; a confluence section in which the first liquid and the second liquid merge with each other to form a mixed liquid; and a gas flow path through which a gas for jetting the mixed liquid passes. At least part of a wall portion defining the confluence section is composed of a gas-permeable membrane that is impermeable to the mixed liquid and permeable to the gas.

Abstract: A sprayer includes: a sprayer body; a nozzle extending from the sprayer body; and an irradiation unit disposed on a leading end of the nozzle and emitting light that is oriented and diffuses in a leading end direction of the nozzle. The nozzle includes: an elongated nozzle body extending from the sprayer body and having a curved portion on a leading end side; and a nozzle head disposed on a leading end of the nozzle body. The irradiation unit is arranged inside a curve shape of the curved portion.

Abstract: A sprayer includes: a sprayer body; a nozzle extending from the sprayer body; and an irradiation unit disposed on a leading end of the nozzle and emitting light that is oriented and diffuses in a leading end direction of the nozzle. The nozzle includes: an elongated nozzle body extending from the sprayer body and having a curved portion on a leading end side; and a nozzle head disposed on a leading end of the nozzle body. The irradiation unit is arranged inside a curve shape of the curved portion.

Abstract: A porous structure includes a polysaccharide and having a multitude of pores wherein an average pore size of the pores is not smaller than 40 ?m and a ratio of the number of pores having a pore size not smaller than 50 ?m to the total number of the pores is not less than 30%. The porous structure improves the solubility of a polysaccharide in water.