Patents by Inventor Miho Kataoka

Miho Kataoka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nonalcoholic steatohepatitis model rodent and fatty liver model rodent
    Patent number: 8278499
    Abstract: Disclosed is a nonhuman animal showing the symptoms of human nonalcoholic steatohepatitis which is obtained by transplanting human hepatocytes into an immunodeficient hepatopathic nonhuman animal to produce a chimeric nonhuman animal and then transplanting human hepatocytes that are propagated in the body of the chimeric nonhuman animal into an immunodeficient hepatopathic nonhuman animal of the same species as the immunodeficient hepatopathic nonhuman animal described above, as well as a nonhuman animal showing the symptoms of human fatty liver which is obtained by transplanting human hepatocytes into an immunodeficient hepatopathic nonhuman animal to produce a chimeric nonhuman animal.
    Type: Grant
    Filed: June 13, 2007
    Date of Patent: October 2, 2012
    Assignees: Hiroshima Industrial Promotion Organization, Phoenixbio Co., Ltd., Hiroshima University
    Inventors: Chise Mukaidani, Katsutoshi Yoshizato, Miho Kataoka
  • Method of treating mouse carrying human hepatocytes
    Patent number: 7871980
    Abstract: Human adult hepatocytes are transplanted into an immunodeficient hepatopathy mouse and then human growth hormone is administered to the mouse to thereby elevate twice or more the replacement ratio by the human adult hepatocytes having been transplanted. Further, human growth hormone is administered to an immunodeficient hepatopathy mouse carrying human young hepatocytes transplanted thereinto so as to improve fatty liver of the mouse in which about 70% or more of the hepatocytes have been replaced by the human hepatocytes.
    Type: Grant
    Filed: June 30, 2006
    Date of Patent: January 18, 2011
    Assignees: Hiroshima Industrial Promotion Organization, Biointegrence Inc., Riken
    Inventors: Chise Mukaidani, Katsutoshi Yoshizato, Norio Masumoto, Miho Kataoka, Tatsuhiko Tsunoda, Fuyuki Miya
  • Nonalcoholic Steatohepatitis Model Animal and Fatty Liver Model Animal
    Publication number: 20090313710
    Abstract: Disclosed is a nonhuman animal showing the symptoms of human nonalcoholic steatohepatitis which is obtained by transplanting human hepatocytes into an immunodeficient hepatopathic nonhuman animal to produce a chimeric nonhuman animal and then transplanting human hepatocytes that are propagated in the body of the chimeric nonhuman animal into an immunodeficient hepatopathic nonhuman animal of the same species as the immunodeficient hepatopathic nonhuman animal described above, as well as a nonhuman animal showing the symptoms of human fatty liver which is obtained by transplanting human hepatocytes into an immunodeficient hepatopathic nonhuman animal to produce a chimeric nonhuman animal.
    Type: Application
    Filed: June 13, 2007
    Publication date: December 17, 2009
    Inventors: Chise Mukaidani, Katsutoshi Yoshizato, Miho Kataoka
  • Method Of Treating Mouse Carrying Human Hepatocytes
    Publication number: 20090060882
    Abstract: Human adult hepatocytes are transplanted into an immunodeficient hepatopathy mouse and then human growth hormone is administered to the mouse to thereby elevate twice or more the replacement ratio by the human adult hepatocytes having been transplanted. Further, human growth hormone is administered to an immunodeficient hepatopathy mouse carrying human young hepatocytes transplanted thereinto so as to improve fatty liver of the mouse in which about 70% or more of the hepatocytes have been replaced by the human hepatocytes.
    Type: Application
    Filed: June 30, 2006
    Publication date: March 5, 2009
    Inventors: Chise Mukaidani, Katsutoshi Yoshizato, Norio Masumoto, Miho Kataoka, Tatsuhiko Tsunoda, Fuyuki Miya