Patents by Inventor Miho Ohuchi

Miho Ohuchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sustained-release polymer micelle disruptable by HDL
    Patent number: 8574601
    Abstract: A pharmaceutical composition containing a drug encapsulated in a polymer micelle composition containing a first block copolymer having affinity with HDL and a second block copolymer having affinity with a lipoprotein excluding HDL, each block copolymer having a hydrophobic polymer chain segment and a hydrophilic polymer chain segment such that a plurality of block copolymers arrange radially with the hydrophobic segments directed inward and the hydrophilic segments directed outward. In the composition, a detachment of the first block copolymer is induced by HDL adhesion which forms a gap and promotes the release of a drug encapsulated, while the second block copolymer excluding an affinity with HDL controls a release speed of the drug encapsulated.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: November 5, 2013
    Assignee: Nanocarrier Co., Ltd.
    Inventors: Yasuki Kato, Mitsunori Harada, Miho Ohuchi
  • DISRUPTIVE POLYMER MICELLE COMPOSITION
    Publication number: 20120093881
    Abstract: A pharmaceutical composition containing a drug encapsulated in a polymer micelle composition containing a first block copolymer having affinity with HDL and a second block copolymer having affinity with a lipoprotein excluding HDL, each block copolymer having a hydrophobic polymer chain segment and a hydrophilic polymer chain segment such that a plurality of block copolymers arrange radially with the hydrophobic segments directed inward and the hydrophilic segments directed outward. In the composition, a detachment of the first block copolymer is induced by HDL adhesion which forms a gap and promotes the release of a drug encapsulated, while the second block copolymer excluding an affinity with HDL controls a release speed of the drug encapsulated.
    Type: Application
    Filed: February 7, 2011
    Publication date: April 19, 2012
    Applicant: NanoCarrier Co., Ltd.
    Inventors: Yasuki Kato, Mitsunori Harada, Miho Ohuchi
  • Physiologically active polypeptide- or protein-encapsulating polymer micelles, and method for production of the same
    Patent number: 8147868
    Abstract: The invention provides a physiologically active polypeptide- or protein-encapsulating polymer micelle composition derived from a block copolymer comprising hydrophilic segments and hydrophobic segments.
    Type: Grant
    Filed: April 25, 2007
    Date of Patent: April 3, 2012
    Assignee: Nanocarrier Co., Ltd.
    Inventors: Miho Ohuchi, Mitsunori Harada, Yuko Amano, Yasuki Kato
  • Physiologically Active Polypeptide- or Protein-Encapsulating Polymer Micelles, and Method for Production of the Same
    Publication number: 20090291130
    Abstract: The invention provides a physiologically active polypeptide- or protein-encapsulating polymer micelle composition derived from a block copolymer comprising hydrophilic segments and hydrophobic segments.
    Type: Application
    Filed: April 25, 2007
    Publication date: November 26, 2009
    Inventors: Miho Ohuchi, Mitsunori Harada, Yuko Amano, Yasuki Kato