Patents by Inventor Miho Shida

Miho Shida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cationic phospholipids for transfection
    Patent number: 6187760
    Abstract: A novel class of cationic phospholipids and novel method for their synthesis are disclosed. The class of phospholipids comprises phosphotriester derivatives of phosphoglycerides and sphingolipids. It has been unexpectedly found that liposomes comprising one or more of these cationic phospholipids are effective in the lipofection of nucleic acids. These novel phospholipids are particularly attractive because of they are not only effective in lipofection, but are extremely cheap and easy to male.
    Type: Grant
    Filed: February 5, 1999
    Date of Patent: February 13, 2001
    Assignee: Northwestern University
    Inventors: Gary W. Ashley, Robert C. MacDonald, Miho Shida
  • Cationic phospholipids for transfection
    Patent number: 5891714
    Abstract: Cationic phospholipids and their use in treating pathogen-associated disease are disclosed. The class of phospholipids comprises the phosphotriester derivatives of phosphoglycerides and sphingolipids. Liposomes comprising one or more of the cationic phospholipids are effective in the lipofection of nuclidic acids and are therefore useful in methods of treating disease.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: April 6, 1999
    Assignee: Northwestern University
    Inventors: Gary W. Ashley, Robert C. MacDonald, Miho Shida
  • Cationic phospholipids for transfection
    Patent number: 5855910
    Abstract: A novel class of cationic phospholipids and novel method for their synthesis are disclosed. The class of phospholipids comprises phosphotriester derivatives of phosphoglycerides and sphingolipids. It has been unexpectedly found that liposomes comprising one or more of these cationic phospholipids are effective in the lipofection of nucleic acids. These novel phospholipids are particularly attractive because of they are not only effective in lipofection, but are extremely cheap and easy to make.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: January 5, 1999
    Assignee: Northwestern University
    Inventors: Gary W. Ashley, Robert C. MacDonald, Miho Shida
  • Cationic phospholipids for transfection
    Patent number: 5780053
    Abstract: A novel class of cationic phospholipids and novel method for their synthesis are disclosed. The class of phospholipids comprises phosphotriester derivatives of phosphoglycerides and sphingolipids. It has been unexpectedly found that liposomes comprising one or more of these cationic phospholipids are effective in the lipofection of nucleic acids. These novel phospholipids are particularly attractive because of they are not only effective in lipofection, but are extremely cheap and easy to make.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 14, 1998
    Assignee: Northwestern University
    Inventors: Gary W. Ashley, Robert C. MacDonald, Miho Shida
  • Cationic phospholipids for transfection
    Patent number: 5688958
    Abstract: A novel class of cationic phospholipids and novel method for their synthesis are disclosed. The class of phospholipids comprises phosphotriester derivatives of phosphoglycerides and sphingolipids. It has been unexpectedly found that liposomes comprising one or more of these cationic phospholipids are effective in the lipofection of nucleic acids. These novel phospholipids are particularly attractive because of they are not only effective in lipofection, but are extremely cheap and easy to make.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: November 18, 1997
    Assignee: Northwestern University
    Inventors: Gary W. Ashley, Robert C. MacDonald, Miho Shida
  • Cationic phospholipids for transfection
    Patent number: 5686620
    Abstract: A novel class of cationic phospholipids and novel method for their synthesis are disclosed. The class of phospholipids comprises phosphotriester derivatives of phosphoglycerides and sphingolipids. It has been unexpectedly found that liposomes comprising one or more of these cationic phospholipids are effective in the lipofection of nucleic acids. These novel phospholipids are particularly attractive because of they are not only effective in lipofection, but are extremely cheap and easy to make.
    Type: Grant
    Filed: September 1, 1995
    Date of Patent: November 11, 1997
    Assignee: Northwestern University
    Inventors: Gary W. Ashley, Robert C. MacDonald, Miho Shida
  • Cationic phospholipids for transfection
    Patent number: 5661018
    Abstract: A novel class of cationic phospholipids and novel method for their synthesis are disclosed. The class of phospholipids comprises phosphotriester derivatives of phosphoglycerides and sphingolipids. It has been unexpectedly found that liposomes comprising one or more of these cationic phospholipids are effective in the lipofection of nucleic acids. These novel phospholipids are particularly attractive because of they are not only effective in lipofection, but are extremely cheap and easy to make.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: August 26, 1997
    Assignee: Northwestern University
    Inventors: Gary W. Ashley, Robert C. MacDonald, Miho Shida
  • Cationic phospholipids for transfection
    Patent number: 5651981
    Abstract: A novel class of cationic phospholipids and novel method for their synthesis are disclosed. The class of phospholipids comprises phosphotriester derivatives of phosphoglycerides and sphingolipids. It has been unexpectedly found that liposomes comprising one or more of these cationic phospholipids are effective in the lipofection of nucleic acids. These novel phospholipids are particularly attractive because of they are not only effective in lipofection, but are extremely cheap and easy to make.
    Type: Grant
    Filed: March 29, 1994
    Date of Patent: July 29, 1997
    Assignee: Northwestern University
    Inventors: Gary W. Ashley, Robert C. MacDonald, Miho Shida