Patents by Inventor Mika SUGA

Mika SUGA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL COMPOSITION
    Publication number: 20240052345
    Abstract: The present invention provides novel antisense oligonucleotide pharmaceutical compositions having higher RNA aggregate-removing activity than conventional pharmaceutical compositions. The pharmaceutical composition of the present invention contains an oligonucleotide having any base sequence of a repeated sequence in which cytosine-adenine-guanine trinucleotides are repeated 5 to 13 times, from the 5? end to the 3? end, and the oligonucleotide has a mixmer structure containing at least two types of RNase H inactive nucleotide analogs. The present invention provides the pharmaceutical composition of the present invention used for the treatment of some symptoms of myotonic dystrophy type 1 disease.
    Type: Application
    Filed: December 22, 2021
    Publication date: February 15, 2024
    Applicants: RIKEN, HYOGO COLLEGE OF MEDICINE
    Inventors: Haruhisa INOUE, Mika SUGA, Takayuki KONDO, Takashi KIMURA
  • Evaluation device, observation device, and program for identifying cell differentiation
    Patent number: 11222423
    Abstract: An evaluation device includes a state determination unit which is configured to determine a state of cells which are an observation target under non-standard conditions on the basis of information acquired from an image of cells under standard conditions.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: January 11, 2022
    Assignees: Nikon Corporation, National Institutes Of Biomedical Innovation, Health And Nutrition
    Inventors: Hiroaki Kii, Yasujiro Kiyota, Takayuki Uozumi, Miho Furue, Mika Suga
  • METHOD FOR PRODUCING NEURAL STEM CELLS, MEDIUM, SUPPLEMENT, SUPPLEMENT SET, MEDIUM KIT, AND CELL CULTURE DEVICE
    Publication number: 20190218514
    Abstract: The present invention provides a method for producing neural stem cells, the method including a culture step of culturing cells using a medium that contains a TGF-? receptor inhibitor and a protein kinase C inhibitor. The method for producing neural stem cells is a method that includes a first culture step of culturing cells using a first medium that does not contain a TGF-? receptor inhibitor and a protein kinase C inhibitor, and a second culture step of culturing the cells using a second medium that contains a TGF-? receptor inhibitor and a protein kinase C inhibitor, after the first culture step. The method for producing neural stem cells is a method that includes a first culture step of culturing cells using a first medium that contains ascorbic acid or an ascorbic acid derivative, and a second culture step of culturing the cells using a second medium that contains a TGF-? receptor inhibitor and a protein kinase C inhibitor, after the first culture step.
    Type: Application
    Filed: May 26, 2017
    Publication date: July 18, 2019
    Inventors: Hiroaki KII, Yasujiro KIYOTA, Takayuki UOZUMI, Miho FURUE, Mika SUGA
  • EVALUATION DEVICE, OBSERVATION DEVICE, AND PROGRAM
    Publication number: 20190087956
    Abstract: An evaluation device includes a state determination unit which is configured to determine a state of cells which are an observation target under non-standard conditions on the basis of information acquired from an image of cells under standard conditions.
    Type: Application
    Filed: September 7, 2018
    Publication date: March 21, 2019
    Inventors: Hiroaki KII, Yasujiro KIYOTA, Takayuki UOZUMI, Miho FURUE, Mika SUGA