Abstract: The invention provides a method for the prophylaxis, improvement, or treatment of inflammatory bowel disease, multiple sclerosis, and psoriasis by administering to a subject an effective amount of an isolated anti-human CD81 antibody capable of binding to a peptide region consisting of the amino acid sequence of amino acid numbers 80 to 175 of SEQ ID NO:22.

Abstract: The invention provides a method for the prophylaxis, improvement, or treatment of inflammatory bowel disease, multiple sclerosis, and psoriasis by administering to a subject an effective amount of an isolated anti-human CD81 antibody capable of binding to a peptide region consisting of the amino acid sequence of amino acid numbers 80 to 175 of SEQ ID NO:22.

Abstract: The present invention provides an anti-CD81 antibody usable as a pharmaceutical product for human. Specifically, the present invention provides an anti-human CD81 antibody capable of binding to a peptide region consisting of the amino acid sequence of the amino acid numbers 80 to 175 in the amino acid sequence shown in SEQ ID NO:22.

Abstract: The present invention provides an anti-CD81 antibody usable as a pharmaceutical product for human. Specifically, the present invention provides an anti-human CD81 antibody capable of binding to a peptide region consisting of the amino acid sequence of the amino acid numbers 80 to 175 in the amino acid sequence shown in SEQ ID NO:22.

Abstract: The present invention provides an anti-CD81 antibody usable as a pharmaceutical product for human. Specifically, the present invention provides an anti-human CD81 antibody capable of binding to a peptide region consisting of the amino acid sequence of the amino acid numbers 80 to 175 in the amino acid sequence shown in SEQ ID NO:22.

Abstract: A pedestrian safety device for automotive vehicle (1) having a hood (2) being hinged and releasably latched to the vehicle body. An actuator member (6) is arranged transversally inside the upper forward region of the vehicle (1) and the ends of the actuator member respectively slideably hinged (11) in a respective inclining guide track (12a) extending rearwards within the vehicle (1). The hinges (11) are arranged to carry a respective first lifting member (14) arranged to carry a respective first lifting member (14) arranged for vertical sliding in respect to the vehicle body. The first lifting members (14) are arranged below the hood (2) such that they will be brought to uplift the hood (2) in the region of its leading edge (2a) upon the hinges (11) carrying it being translated up the inclining guide tracks (12a) as a result of collision impact on the actuator member (6).

Abstract: The present patent application relates to a pedestrian safety device for automotive vehicles (1) having a hood (2) being hinged and releasably latched to the vehicle body. An actuator member (6) is arranged transversally inside the upper forward region of said vehicle (1) and the ends of the actuator member respectively slideably hinged (11) in a respective inclining guide track (12a) extending rearwards within said vehicle (1). The hinges (11) are arranged to carry a respective first lifting member (14) arranged for vertical sliding in respect to the vehicle body. The first lifting members (14) are arranged below the hood (2) such that they will be brought to uplift the hood (2) in the region of its leading edge (2a) upon said hinges (11) carrying it being translated up said inclining guide tracks (12a) as a result of collision impact on said actuator member (6).

Abstract: A corner bending unit (2) for achieving a reciprocating movement in a tool holder (14) for a bending tool (12), the tool holder being articulated to a foundation (4) via parallel links (16, 18). The corner bending unit (2) has a pneumatic cylinder (38) with a piston rod (36) which is pivotally (34) joined to a triangle link (30), which is in turn pivotally joined (32) to one end of a link (28), the other end of which being joined to a pivot point (22) on the tool holder. The triangle link is pivotally carried in the foundation (4) about a pivot point (24) and forms, together with the link (28), a knee-joint mechanism (28, 30), which, under the influence of the cylinder (38) piston rod (36), can be moved from the bent-out position shown to a completely extended position, the tool holder (14) being movable between a starting position and a work position. The pivot point (22) is common to parallel link (16) and the link (28), and pivot point (24) is common to parallel link (18) and the triangle link (30).

Abstract: The invention relates to a clinching press comprising a press tool (52) and a prebending unit (1) to produce a reciprocating movement in a tool holder (14) of a prebending tool (12), said tool holder being articulated to a foundation (2). The prebending unit (1) has a pressure rod (50) coupled to the press tool (52) and a knee-joint mechanism (28, 30), joined, on the one hand, to a pivot point (36) on the tool holder (14) and, on the other hand, to a fixed pivot point (34) on the foundation (2). The pressure roller (46) is freely rotatably mounted at the connecting point (32) of the links (28, 30). The knee-joint mechanism (28, 30) has a gas pressure spring (38, 42) for returning the mechanism to the starting position shown.