Patents by Inventor Mikael MAZIGHI

Mikael MAZIGHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CLOT RETRIEVAL DEVICES AND THERAPEUTIC USE THEREOF
    Publication number: 20220202429
    Abstract: The present invention relates to improved clot retrieval devices, wherein at least the part of the device intended to be in contact with a clot is coated with at least one chromatin binding agent selected from the group consisting of digoxigenin, a digoxigenin derivative, distamycin and a distamycin derivative. The present invention also relates to a method of producing said improved clot retrieval device. The present invention also relates to a method of prevention and/or treatment of stroke in a subject, comprising removing at least one clot using the clot retrieval device coated with said least one chromatin binding agent.
    Type: Application
    Filed: December 29, 2021
    Publication date: June 30, 2022
    Applicants: BALT EXTRUSION, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE PARIS 13 - PARIS NORD, UNIVERSITE DE PARIS, FONDATION A DE ROTHSCHILD
    Inventors: Jean-Philippe Mickael DESILLES, Mikael MAZIGHI, Giuseppina CALIGIURI, Antonino NICOLETTI